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Researchers identify the cellular glitches underlying a rare genetic disorder

The cellular glitches underlying a rare genetic disorder called activated PI3K Delta syndrome 2 (APDS2) have been identified by researchers at the Garvan Institute of Medical Research. The disorder is caused by genetic variations that disrupt immune cell signaling through a protein called PI3K.

21 Mar 2023

Supervised exercise training is safe and may improve quality of life for many people with heart failure

For many people who have heart failure, supervised exercise training is safe and may offer substantial improvement in exercise capacity and quality of life, even more than medications, according to a new, joint scientific statement from the American Heart Association and the American College of Cardiology.

21 Mar 2023

Machine learning programs use routinely collected hospital data to predict risk of death

If you've ever been admitted to hospital or visited an emergency department, you've likely had an electrocardiogram, or ECG, a standard test involving tiny electrodes taped to your chest that checks your heart's rhythm and electrical activity.

21 Mar 2023

Girls born to obese mothers have a high risk of developing obesity

Women with obesity may share risk for the disease with their daughters, but not their sons, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

21 Mar 2023

Advanced surgical therapy proves to be effective for patients with uveal melanoma liver metastases

An advanced surgical therapy has proved considerably more efficacious than conventional treatments for patients with melanoma in the eye (uveal) that has spread to the liver, a University of Gothenburg study shows.

21 Mar 2023

ACTG publishes study to simplify the administration of hepatitis C treatment

The AIDS Clinical Trials Group, the world's largest HIV research network, is announcing the publication of "Perspectives on Adherence from the ACTG 5360 MINMON Trial: A Minimum Monitoring Approach with 12 Weeks of Sofosbuvir/Velpatasvir in Chronic Hepatitis C Treatment" in the journal Clinical Infectious Diseases.

21 Mar 2023

Gut microbiota-derived biomarkers for identifying patients with fatty liver disease

A recent study at the University of Jyväskylä (Finland) compared the gut microbiota and gut-derived metabolites between healthy controls and individuals with fatty liver.

21 Mar 2023

UTSW expert advises screening by 55 for people with family history of age-related macular degeneration

Patients with a family history of age-related macular degeneration (AMD), the leading cause of permanent vision loss in those older than 60, should visit an ophthalmologist by age 55 to be screened for signs of the disease, advises an expert at UT Southwestern Medical Center.

21 Mar 2023

Sleep disorders contribute to cognitive dysfunction in women with multiple sclerosis

For women with multiple sclerosis who report cognitive dysfunction - one of the most common and disabling symptoms of the disease - sleep disorders such as insomnia and sleep apnea may contribute to the perceived decline, a Michigan Medicine study suggests.

21 Mar 2023

Keeping stem cells clean and tidy is an integral step to promoting a long healthspan

In humanity's ongoing quest for the elixir of life, the science keeps pointing to stem cells. Research increasingly shows that maintaining stem cell fitness promotes a long healthspan, and new findings show keeping stem cells clean and tidy is an integral step.

21 Mar 2023

People conceived by IVF are not at increased risk of obstetric or perinatal complications, study finds

There's little evidence to suggest that children conceived as a result of fertility treatment are at any greater risk of pregnancy complications or worse birth outcomes than their naturally conceived peers, finds a long-term study, published in the open access journal BMJ Medicine.

21 Mar 2023

Global review reveals criminalization of abortion in almost all countries

Almost all countries around the globe criminalize abortion in some circumstances, despite the public health risks and impact on human rights, finds a review of the scope of penalties for the procedure in 182 nations, published in the open access journal BMJ Global Health.

21 Mar 2023

Blood News and Research

Researchers identify the cellular glitches underlying a rare genetic disorder

Supervised exercise training is safe and may improve quality of life for many people with heart failure

Machine learning programs use routinely collected hospital data to predict risk of death

Girls born to obese mothers have a high risk of developing obesity

Advanced surgical therapy proves to be effective for patients with uveal melanoma liver metastases

ACTG publishes study to simplify the administration of hepatitis C treatment

Gut microbiota-derived biomarkers for identifying patients with fatty liver disease

UTSW expert advises screening by 55 for people with family history of age-related macular degeneration

Sleep disorders contribute to cognitive dysfunction in women with multiple sclerosis

Keeping stem cells clean and tidy is an integral step to promoting a long healthspan

People conceived by IVF are not at increased risk of obstetric or perinatal complications, study finds

Global review reveals criminalization of abortion in almost all countries

MHRA to introduce a series of new measures for streamlining clinical trial approvals

Avanced genome editing technology could be used as a one-time treatment for CD3 delta SCID

Discovery of 16th century coronavirus in France

Childhood common colds help protect against COVID-19

New treatment using nanoparticles can repair lymphatic vessel pumping

Investigating how gut microbiota affect neuroplasticity and neurodevelopment

Study of vascular function in men eating high-fat and low-fat ground beef

Review explores trehalose's effects on metabolism and gut microflora

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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