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Immunological interactions between asthma, obesity, and the microbiota

This study summarizes the mechanisms associated with obesity-aggravated asthma.

18 Jan 2023

Genotyping technology may help increase the number of kidney transplantations and reduce wait times

ABO blood-type compatibility between organ donors and recipients is crucial for safe transplantations. Across the different ABO blood groups, longer wait-times for a kidney transplant are often experienced by patients who have type B blood because it is a less common ABO blood type, resulting in fewer donors.

18 Jan 2023

Research explores the utility of epigenetically predicted BMI

DNA methylation is an accurate predictor of current BMI and a poor predictor of future BMI.

18 Jan 2023

T-cell immunity and antibody responses against SARS-CoV-2 among individuals registered in the Bangkok home health care service

Researchers performed an observational study among COVID-19 patients and their close contacts registered with the Bangkok home health care services in Thailand.

18 Jan 2023

Researchers use single-cell RNA-sequencing to study the aging peripheral blood in mice

A new research paper was published on the cover of Aging (listed as "Aging (Albany NY)" by Medline/PubMed and "Aging-US" by Web of Science) Volume 15, Issue 1, entitled, "Single-cell transcriptomics of peripheral blood in the aging mouse."

18 Jan 2023

Henry Ford Health nephrologist-led study evaluates and validates vascular monitoring technology

Research led by Henry Ford Health's Lalathaksha Kumbar, M.D., evaluated and validated a remote access monitoring technology that can predict vascular access blockages in dialysis patients.

18 Jan 2023

Cedars-Sinai's Stem Cell and Bone Marrow Transplant Program recognized with two major hallmarks of quality

The Stem Cell and Bone Marrow Transplant Program at Cedars-Sinai Cancer was recently recognized with two important hallmarks of quality: official accreditation for CAR T-cell therapy, and a third year in a row ranking among the top adult bone marrow transplant programs in the U.S.

18 Jan 2023

Upregulation of Robo4 expression reduces mortality from severe infection

The researchers screened a library of drugs using a mouse endothelial cell line to identify pathways that are involved in the regulation of Robo4 and found that two competitive SMAD signaling pathways appear to regulate Robo4 expression.

18 Jan 2023

What older Americans need to know about taking Paxlovid

A new coronavirus variant is circulating, the most transmissible one yet. Hospitalizations of infected patients are rising. And older adults represent nearly 90% of U.S. deaths from covid-19 in recent months, the largest portion since the start of the pandemic.

18 Jan 2023

Exposure to World Trade Center particulate matter accelerates cognitive deterioration in mice model of Alzheimer's

Mice exposed to World Trade Center dust exhibit a significant impairment in spatial recognition and short- and long-term memory, as well as changes in genes related to immune-inflammatory responses and blood-brain barrier disruption, according to a study conducted by researchers from the Icahn School of Medicine at Mount Sinai and published January 17 in the Journal of Alzheimer's Disease.

17 Jan 2023

New ‘smart patch’ can detect proinflammatory biomarkers of neurodegenerative diseases

A leading Swansea University scientist has developed a new 'smart patch' that can detect proinflammatory biomarkers of neurodegenerative diseases (such as Parkinson's and Alzheimer's) through the use of microneedle technology.

17 Jan 2023

New tool for noninvasive imaging can help illuminate hard-to-access brain structures

Talk about a bright idea: Thanks to chemists at Rice University and Stanford University, lighting up the brain is no longer just a figure of speech.

17 Jan 2023

Dementia risk in women may be reduced by hormone replacement therapy

Women are at greater risk for dementia than men, probably because of waning estrogen levels following menopause. Estrogen is a key female hormone linked to reproductive, sexual, and neurological functions. A new study published in the journal Alzheimer's Research & Therapy examines how hormone replacement works in women with a high genetic risk for AD.

17 Jan 2023

Probiotic diminishes S. aureus bacterial colonization, Phase 2 trial shows

A promising approach to control Staphylococcus aureus bacterial colonization in people - using a probiotic instead of antibiotics - was safe and highly effective in a Phase 2 clinical trial.

17 Jan 2023

Novel peptide suppresses the damaging lung inflammation seen in ARDS

A novel peptide designed by University of California, Irvine researchers has been found to suppress the damaging lung inflammation seen in acute respiratory distress syndrome, or ARDS.

17 Jan 2023

Future COVID-19 control will require vaccines that induce better mucosal immunity

In a recent study posted to the medRxiv* preprint server, researchers in France explored the relationship between long-term immunoglobulin (Ig)-A response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and taste and smell disorders.

17 Jan 2023

Association between coronary artery calcium dispersion and mortality

Scientists determine whether the estimation of coronary artery calcium dispersion could determine all-cause and causes of specific mortality.

17 Jan 2023

Researchers identify plasma metabolomic markers for the Mediterranean diet among pregnant women

A recent study identifies blood metabolomic markers and metabolite panels linked to the Mediterranean diet in pregnant women.

17 Jan 2023

Study finds no difference in the survival benefit of two diuretics for heart failure patients

Two drugs widely used to treat adults with heart failure – furosemide and torsemide – showed no difference in their ability to improve patient survival when compared, according to findings from a clinical trial supported by the National Institutes of Health.

17 Jan 2023

What are the major findings of long COVID research?

Researchers explored existing literature on long coronavirus disease (COVID). They highlighted key immunological findings, similarities with other diseases, symptoms, and associated pathophysiological mechanisms, and diagnostic and therapeutic options, including COVID-19 vaccinations.

17 Jan 2023

Blood News and Research

Immunological interactions between asthma, obesity, and the microbiota

Genotyping technology may help increase the number of kidney transplantations and reduce wait times

Research explores the utility of epigenetically predicted BMI

T-cell immunity and antibody responses against SARS-CoV-2 among individuals registered in the Bangkok home health care service

Researchers use single-cell RNA-sequencing to study the aging peripheral blood in mice

Henry Ford Health nephrologist-led study evaluates and validates vascular monitoring technology

Cedars-Sinai's Stem Cell and Bone Marrow Transplant Program recognized with two major hallmarks of quality

Upregulation of Robo4 expression reduces mortality from severe infection

What older Americans need to know about taking Paxlovid

Exposure to World Trade Center particulate matter accelerates cognitive deterioration in mice model of Alzheimer's

New ‘smart patch’ can detect proinflammatory biomarkers of neurodegenerative diseases

New tool for noninvasive imaging can help illuminate hard-to-access brain structures

Dementia risk in women may be reduced by hormone replacement therapy

Probiotic diminishes S. aureus bacterial colonization, Phase 2 trial shows

Novel peptide suppresses the damaging lung inflammation seen in ARDS

Future COVID-19 control will require vaccines that induce better mucosal immunity

Association between coronary artery calcium dispersion and mortality

Researchers identify plasma metabolomic markers for the Mediterranean diet among pregnant women

Study finds no difference in the survival benefit of two diuretics for heart failure patients

What are the major findings of long COVID research?

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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