SARS CoV 2 News and Research

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Study identifies three novel broad-spectrum SARS-CoV-2 cell entry inhibitors

Researchers from the National Institutes of Health (NIH) and Cornell University in the U.S. just described several new inhibitors of human coronavirus spike proteins by screening a library of approved drugs with SARS-S and MERS-S pseudotyped particle entry assays. Their exciting findings are currently available on the bioRxiv preprint server.

13 Jul 2020

Bat research critical to help predict and prevent the next pandemic

The current SARS-CoV-2 pandemic has a likely connection to bats, and the next viral outbreak probably will too, unless scientists can quickly learn more about the thousands of viruses carried by one of the most diverse mammals on the planet.

13 Jul 2020

Serology distinguishes children with MIS-C associated with COVID-19

Researchers in the United States say that measuring antibody titers against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may help to distinguish between multisystem inflammatory syndrome in children (MIS-C) and other clinically similar syndromes.

13 Jul 2020

Skin rash may be a symptom of COVID-19

Researchers at King’s College London and Zoe Global Ltd have conducted a study suggesting that skin rashes could be valuable predictors of coronavirus disease 2019 (COVID-19).

13 Jul 2020

NUS teams develop three nasopharyngeal swab designs for COVID-19 testing

Since the outbreak of COVID-19, there has been a global surge in demand for nasopharyngeal (NP) swabs, a key element in testing for SARS-CoV-2. Singapore is no exception. Commercially available NP swabs used in COVID-19 test kits are often out of stock due to supply chain disruptions.

13 Jul 2020

EKF introduces novel molecular transport media for dual COVID-19 and influenza sampling

EKF Diagnostics the global in vitro diagnostics company, announces that it has added a novel viral transport media for the safe sample handling and testing of multiple infectious diseases from a single swab to its product range.

From EKF Diagnostics 13 Jul 2020

South Carolina reports first cases of coronavirus-related pediatric inflammatory syndrome

Coronavirus-related pediatric inflammatory syndrome, also known as multisystem inflammatory syndrome in children, or MIS-C, is a rare inflammatory condition that affects children and adolescents and is tied to exposure to the novel coronavirus.

13 Jul 2020

Researchers develop COVID-19 mortality risk calculator

A new study published in July 2020 on the preprint server medRxiv describes the use of machine learning to provide a better understanding of the risk factors in large and mixed groups. The use of algorithms can help objectively evaluate these factors and perhaps capture interactions that could be missed in a purely observational study.

13 Jul 2020

Dysfunctional T cells present at high levels in severe COVID-19

Now, a new study by researchers at Saarland University, Germany, and published on the preprint server medRxiv in July 2020 shows that there are higher levels of anti-SARS-CoV-2 T cells, which show significant alterations in the phenotype and function.

12 Jul 2020

No unique viral sequences found in pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2

In contrast to previous hypotheses, researchers from the University College London and Great Ormond Street Hospital for Children NHS Foundation Trust found no evidence of unique viral sequences from patients with pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS). Their study is published on the medRxiv* preprint server.

12 Jul 2020

Digestive manifestations common but mild among hospitalized COVID-19 patients

A team of 121 researchers from the United States and Canada reports that while digestive manifestations seem to be common among people hospitalized with coronavirus disease 2019 (COVID-19), the majority appear to be mild and not associated with severe clinical outcomes.

12 Jul 2020

Increasing level of SARS-CoV-2 detected in Montpellier wastewater

Researchers at The French National Centre for Scientific Research have identified a recent increase in the amount of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA at the main wastewater treatment plant (WWTP) of the Montpellier metropolitan area.

12 Jul 2020

Membrane makeover turns N95 respirator into a reusable mask

A polyimide membrane with regularly sized and spaced pores turns the N95 respirator into a reusable mask for protection against COVID-19.

12 Jul 2020

Single-cell RNA sequencing analysis reveals patients' immune responses to severe COVID-19

A new single-cell RNA sequencing analysis of more than 59,000 cells from three different patient cohorts provides a detailed look at patients' immune responses to severe cases of COVID-19.

12 Jul 2020

Study documents intrauterine transmission of SARS-CoV-2 infection during pregnancy

A baby girl in Texas - born prematurely to a mother with COVID-19 - is the strongest evidence to date that intrauterine (in the womb) transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can occur, reports The Pediatric Infectious Disease Journal, the official journal of The European Society for Paediatric Infectious Diseases.

12 Jul 2020

Concentration of lopinavir and hydroxychloroquine not sufficient to fight novel coronavirus

Lopinavir is a drug against HIV, hydroxychloroquine is used to treat malaria and rheumatism. Until recently, both drugs were regarded as potential agents in the fight against the coronavirus SARS-CoV-2.

11 Jul 2020

FIND and Unitaid launch call for EOI to fill major diagnostic gaps in COVID-19 detection

The Foundation for Innovative New Diagnostics and Unitaid announced today that the organizations have launched a call for expressions of interest to accelerate the availability and manufacturing scale-up of rapid diagnostic tests for the detection of SARS-CoV-2 antigens. Reliable, affordable Ag RDTs have been identified as key tools in the global response to COVID-19, as they could enable robust detection of active SARS-CoV-2 infection for both patient management and contact tracing purposes in decentralized settings.

10 Jul 2020

SARS CoV 2 News and Research

Study identifies three novel broad-spectrum SARS-CoV-2 cell entry inhibitors

Bat research critical to help predict and prevent the next pandemic

Serology distinguishes children with MIS-C associated with COVID-19

Skin rash may be a symptom of COVID-19

NUS teams develop three nasopharyngeal swab designs for COVID-19 testing

EKF introduces novel molecular transport media for dual COVID-19 and influenza sampling

South Carolina reports first cases of coronavirus-related pediatric inflammatory syndrome

Researchers develop COVID-19 mortality risk calculator

Dysfunctional T cells present at high levels in severe COVID-19

No unique viral sequences found in pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2

Digestive manifestations common but mild among hospitalized COVID-19 patients

Increasing level of SARS-CoV-2 detected in Montpellier wastewater

Membrane makeover turns N95 respirator into a reusable mask

Single-cell RNA sequencing analysis reveals patients' immune responses to severe COVID-19

Study documents intrauterine transmission of SARS-CoV-2 infection during pregnancy

Concentration of lopinavir and hydroxychloroquine not sufficient to fight novel coronavirus

FIND and Unitaid launch call for EOI to fill major diagnostic gaps in COVID-19 detection

New clinical trial to assess safety and efficacy of convalescent plasma to prevent COVID-19

Researchers estimate global undercounting of COVID-19 cases

What people know and how they behave during COVID-19: Canadian perspective

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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