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Primary care physicians report burnout at twice the rate of other health care professionals

Clinician burnout is a growing public health concern, with the National Academy of Sciences reporting that 35-54% of U.S. nurses and physicians exhibit substantial symptoms of burnout.

20 May 2020

Main receptors used by SARS-CoV-2 for cell entry are absent in the human placenta

Although severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is unlikely to infect human placenta through the canonical cell entry mediators, Wayne State University researchers showed that other interacting proteins may still play an important role during the viral infection. The study is currently available on the preprint server bioRxiv.

20 May 2020

Study shows engineered SARS-CoV-2 spike protein may be utilized for vaccine development

In a new study available on the preprint server bioRxiv, researchers demonstrate how the conformation of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein (S-protein) can be controlled with the rational construct design, providing a framework for S-protein structure engineering in vaccine/drug development.

20 May 2020

African American communities more burdened by COVID-19, say researchers

A new study conducted by researchers at Florida International University, Miami, has found that communities in the United States with a high density of African Americans are disproportionately burdened with the adverse outcomes of coronavirus disease 2019 (COVID-19).

20 May 2020

Certain corticosteroid could improve severe COVID-19, say researchers

Researchers at Wayne State University and Henry Ford Health System in Michigan have conducted a study indicating that the corticosteroid methylprednisolone could improve outcomes among patients with severe coronavirus disease 2019 (COVID-19).

20 May 2020

Immunologists propose possible molecular mechanism for the deadly respiratory syndrome

Research into how the SARS-CoV-2 virus induces death is suggesting potential treatments for its most destructive complications.

20 May 2020

Moderna’s coronavirus vaccine candidate shows promise in phase I trial

Moderna, who partnered with the National Institutes of Health, announced that its candidate vaccine appeared to be safe when administered to eight healthy volunteers. The vaccine also stimulated an immune response to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes the coronavirus disease (COVID-19).

20 May 2020

Countries that develop a coronavirus vaccine may not share it, health expert warns

The pandemic has sparked a worldwide race to develop a vaccine against the novel coronavirus. But a health expert has warned that the world might face a risk of "vaccine nationalism," wherein countries who will produce a coronavirus vaccine will not share it with others.

20 May 2020

Report describes clinical characteristics and outcomes of children hospitalized with COVID-19

While most children infected with the novel coronavirus have mild symptoms, a subset requires hospitalization and a small number require intensive care.

20 May 2020

Researchers describe new methods to speed up drug approvals during pandemics

In response to the COVID-19 pandemic, researchers from the Massachusetts Institute of Technology have published a pair of studies in a COVID-19 special issue of the Harvard Data Science Review, freely available via open access, describing new methods for accelerating drug approvals during pandemics and for providing more accurate measures of the probabilities of success for clinical trials of vaccines and other anti-infective therapies.

20 May 2020

New drug treatment can reduce risk of death from COVID-19 infection

Researchers in the Ludwig Center at the Johns Hopkins Kimmel Cancer Center report they have identified a drug treatment that could--if given early enough--potentially reduce the risk of death from the most serious complication of Coronavirus disease 2019 (COVID-19), also known as SARS-CoV-2 infection.

20 May 2020

Immunotherapy, steroids restore heart function in children with COVID-related multi-system inflammatory syndrome

Treatment with antibodies purified from donated blood - immune globulin therapy - and steroids restored heart function in the majority of children with COVID-related multi-system inflammatory syndrome, according to new research published yesterday in Circulation, the flagship journal of the American Heart Association.

19 May 2020

Aerosol transmission through new vs. reused N95 masks

The world is grappling with the worst pandemic in over 100 years. Caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus which emerged in China in December 2019 but has now spread across the globe. With a rapid rate of transmission, SARS-CoV-2 has now affected over 4.88 million people and resulted in over 322,000 deaths.

19 May 2020

The use of rheumatoid arthritis drug sarilumab in severe COVID-19 pneumonia

A new study published on the preprint server medRxiv* in May 2020 reports the beneficial effects of the monoclonal antibody sarilumab in severe COVID-19 pneumonia.

19 May 2020

Do parasites protect against SARS-CoV-2?

The world has rarely seen such a readily transmissible infection as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) over the last century. Within five months, the virus has created a Tsunami of COVID-19 positive cases, comprising almost 4.88 million people and causing 322,000 deaths.

19 May 2020

Does COVID-19 infect peripheral blood cells?

The emergence of the novel coronavirus outbreak in December 2019 was followed by its spread on a global scale unparalleled in the last 100 years. At present, it has claimed over 322,000 lives the world over, with over 4.88 million cases having tested positive.

19 May 2020

Gene mutation linked to MEF2C haploinsufficiency syndrome

A collaboration between scientists at the Medical University of South Carolina and clinicians at the Greenwood Genetic Center has yielded new findings about how a particular gene might regulate brain development.

19 May 2020

Did SARS-CoV-2 adapt to humans long before the index case?

A new study from Canada and the U.S. suggests that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may have already been pre-adapted to human transmission when it emerged in late 2019, which means there may be lingering populations of progenitor SARS-CoV-2 adept for human transmission and coronavirus disease (COVID-19) re-emergence. The research is published on the preprint server bioRxiv in May 2020.

19 May 2020

Sleep apnea may increase the risk of severe COVID-19, say researchers

An analysis conducted by researchers at the University of Turku and Turku University Hospital in Finland has suggested that obstructive sleep apnea (OSA) may be a risk factor for severe coronavirus disease 2019 (COVID-2019).

19 May 2020

No SARS-COV-2 among young children in Belgium attending daycare, report researchers

A study conducted by researchers in Belgium has found no evidence to support concerns that asymptomatic young children may be a source of severe acute respiratory syndrome coronavirus disease 2 (SARS-CoV-2) transmission.

19 May 2020

Syndrome News and Research

Primary care physicians report burnout at twice the rate of other health care professionals

Main receptors used by SARS-CoV-2 for cell entry are absent in the human placenta

Study shows engineered SARS-CoV-2 spike protein may be utilized for vaccine development

African American communities more burdened by COVID-19, say researchers

Certain corticosteroid could improve severe COVID-19, say researchers

Immunologists propose possible molecular mechanism for the deadly respiratory syndrome

Moderna’s coronavirus vaccine candidate shows promise in phase I trial

Countries that develop a coronavirus vaccine may not share it, health expert warns

Report describes clinical characteristics and outcomes of children hospitalized with COVID-19

Researchers describe new methods to speed up drug approvals during pandemics

New drug treatment can reduce risk of death from COVID-19 infection

Immunotherapy, steroids restore heart function in children with COVID-related multi-system inflammatory syndrome

Aerosol transmission through new vs. reused N95 masks

The use of rheumatoid arthritis drug sarilumab in severe COVID-19 pneumonia

Do parasites protect against SARS-CoV-2?

Does COVID-19 infect peripheral blood cells?

Gene mutation linked to MEF2C haploinsufficiency syndrome

Did SARS-CoV-2 adapt to humans long before the index case?

Sleep apnea may increase the risk of severe COVID-19, say researchers

No SARS-COV-2 among young children in Belgium attending daycare, report researchers

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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