Syndrome News and Research

RSS

Gulf war illness – one or two diseases?

A study of veterans who have Gulf war syndrome shows that moderate exercise can bring about a spectrum of brain imaging abnormalities, which fall into one of two groups. This could mean that this is a more complicated illness than was first thought. The study was published on December 12, 2019, in the journal Brain Communications.

12 Dec 2019

Scientists develop an approach to vaccinate against gut inflammation

Inflammatory bowel disease (IBD) is an umbrella term that describes many disorders that involve chronic inflammation of the digestive tract, including ulcerative colitis and Crohn's disease. These conditions are tied to certain alternations in the gut flora.

12 Dec 2019

NIH-funded research finds differences in energy use by immune T cells in ME/CFS

New findings published in the Journal of Clinical Investigation suggest that specific immune T cells from people with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) show disruptions in the way they produce energy.

12 Dec 2019

Developments in the search for a Zika vaccine - success in mice and a new platform for flavivirus vaccines

Researchers have vaccinated mice against the Zika virus, whilst others have discovered a new platform for flavivirus vaccines.

12 Dec 2019

Brain imaging of veterans reveals two subtypes of Gulf War illness

Brain imaging of veterans with Gulf War illness show varying abnormalities after moderate exercise that can be categorized into two distinct groups - an outcome that suggests a more complex illness that previously thought.

12 Dec 2019

Epigenome editing could repair genetic brain disorder

A new study published in the journal Nature Communications shows that it may be possible to reverse gene mutations that cause brain disorders, using a very precisely targeted epigenome editing technique. This type of gene editing does not change the gene’s DNA sequence itself but is focused on correcting epigenome changes only. The condition that was corrected in the study is called the WAGR syndrome and is associated with obesity and intellectual disability in people.

11 Dec 2019

Jefferson hotspotting program uses team-based model to addresses hospital 'super utilizers'

The United States faces a crisis in providing complex care for high-need, high-cost individuals--people who often suffer economic, mental and physical challenges.

11 Dec 2019

Treatment combination improves survival in advanced HER2-positive breast cancer patients

Researchers from The University of Texas MD Anderson Cancer Center today reported study results showing the addition of tucatinib to capecitabine (Xeloda) and trastuzumab (Herceptin) significantly improved progression-free survival (PFS) and overall survival (OS) in patients with advanced HER2-positive breast cancer, with and without brain metastasis according to results of the HER2CLIMB clinical trial.

11 Dec 2019

New approach to alter intestinal microbiota and protect against inflammatory diseases

Targeted immunization against bacterial flagellin, a protein that forms the appendage that enables bacterial mobility, can beneficially alter the intestinal microbiota, decreasing the bacteria's ability to cause inflammation and thus protecting against an array of chronic inflammatory diseases, according to a new study by the Institute for Biomedical Sciences and the Neuroscience Institute at Georgia State University.

11 Dec 2019

Study may help explain why deep-brain stimulation does not work for everyone

People with severe Parkinson's disease or other neurological conditions that cause intractable symptoms such as uncontrollable shaking, muscle spasms, seizures, obsessive thoughts and compulsive behaviors are sometimes treated with electric stimulators placed inside the brain.

10 Dec 2019

Study provides most detailed classification of acute myeloid leukemia, myelodysplastic syndrome

Results from a study conducted by St. Jude Children's Research Hospital and the Munich Leukemia Laboratory were presented today as a late-breaking abstract at the American Society of Hematology annual meeting. The study integrates genomic and transcriptomic sequencing to provide the most detailed classification of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) to date.

10 Dec 2019

Researchers aim to exploit DNA mutations in the treatment of blood and bone marrow cancers

In a clinical trial led by Yale Cancer Center and Smilow Cancer Hospital, researchers aim to exploit DNA mutations in the treatment of two blood and bone marrow cancers, a different tacit than the more traditional approach of blunting or switching off genetic mutations linked to cancer.

10 Dec 2019

New free mobile app helps families keep their infants safe

Placing an infant to sleep safely can save lives. A new, free mobile app, Baby be Well, helps families keep their infants safe throughout the first year of life.

10 Dec 2019

Genetic alteration increases risk of Autism and Tourette's impacts on the brain

Lancaster University researchers have discovered, for the first time, how a genetic alteration that increases the risk of developing Autism and Tourette's impacts on the brain.

10 Dec 2019

Risk of specific genetic translocation is higher in patients of African ancestry, shows study

Multiple myeloma is a plasma cell cancer that is more common in patients of African American descent than of European American descent.

10 Dec 2019

Relapsed mantle cell lymphoma patients may benefit from CAR T-cell therapy

A one-year follow-up study led by The University of Texas MD Anderson Cancer Center revealed a majority of patients with mantle cell lymphoma resistant to prior therapies may benefit from treatment with CD19-targeting chimeric antigen receptor (CAR) T-cell therapy.

9 Dec 2019

Pairing chemotherapy azacitidine with enasidenib boosts complete remission in AML patients

A multi-institutional, Phase II study led by The University of Texas MD Anderson Cancer Center showed that pairing standard chemotherapy azacitidine (AZA) with a drug called enasidenib (ENA) measurably boosts complete remission in patients newly diagnosed with a specific form of acute myeloid leukemia (AML).

9 Dec 2019

Venetoclax in combination with azacytidine aids therapy for myelodysplastic syndromes

A new study by Yale Cancer Center and Smilow Cancer Hospital researchers suggests that the drug venetoclax aids therapy for relapsed/refractory myelodysplastic syndromes, especially when paired with azacytidine.

9 Dec 2019

Researchers identify key protein associated with aging

Aging is a dramatic public health issue in the face of the current demographic changes: the proportion of 60 and over in the world's population will almost double by 2050. In this context, a new discovery has just broadened scientific knowledge.

9 Dec 2019

$Experimental immunotherapy can put patients with relapsed or refractory lymphoma into remission$

Experimental immunotherapy can put patients with relapsed or refractory lymphoma into remission

A new, experimental immunotherapy can put patients with B-cell non-Hodgkin lymphoma (NHL) that is resistant to or has come back after multiple other therapies, including CAR T therapy, into remission.

8 Dec 2019

Syndrome News and Research

Gulf war illness – one or two diseases?

Scientists develop an approach to vaccinate against gut inflammation

NIH-funded research finds differences in energy use by immune T cells in ME/CFS

Developments in the search for a Zika vaccine - success in mice and a new platform for flavivirus vaccines

Brain imaging of veterans reveals two subtypes of Gulf War illness

Epigenome editing could repair genetic brain disorder

Jefferson hotspotting program uses team-based model to addresses hospital 'super utilizers'

Treatment combination improves survival in advanced HER2-positive breast cancer patients

New approach to alter intestinal microbiota and protect against inflammatory diseases

Study may help explain why deep-brain stimulation does not work for everyone

Study provides most detailed classification of acute myeloid leukemia, myelodysplastic syndrome

Researchers aim to exploit DNA mutations in the treatment of blood and bone marrow cancers

New free mobile app helps families keep their infants safe

Genetic alteration increases risk of Autism and Tourette's impacts on the brain

Risk of specific genetic translocation is higher in patients of African ancestry, shows study

Relapsed mantle cell lymphoma patients may benefit from CAR T-cell therapy

Pairing chemotherapy azacitidine with enasidenib boosts complete remission in AML patients

Venetoclax in combination with azacytidine aids therapy for myelodysplastic syndromes

Researchers identify key protein associated with aging

Experimental immunotherapy can put patients with relapsed or refractory lymphoma into remission

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News