Syndrome News and Research

RSS

Inner ear gene therapy holds promise for treating patients with hearing loss and dizziness

In a first-of-its-kind study published in the March 1, 2017 edition of Molecular Therapy, researchers from the National Institute on Deafness and Other Communication Disorders and Johns Hopkins University School of Medicine showed that gene therapy was able to restore balance and hearing in genetically modified mice that mimic Usher Syndrome, a genetic condition in humans characterized by partial or total hearing loss, dizziness, and vision loss that worsens over time.

23 Mar 2017

Study links gastrointestinal disturbances of GWI with changes in intestinal microbiota

A new study from the University of South Carolina has found a gastrointestinal link that could help explain many of the health issues facing those with Gulf War Illness (GWI) as well as opening new pathways to treatment options that may improve both gastrointestinal and neurological symptoms associated with the disorder.

23 Mar 2017

UCLA study traces Pavlovian response to small cluster of brain cells

In his famous experiment, Russian scientist Ivan Pavlov rang a bell each time he fed his dogs. Soon, the dogs began drooling in anticipation when they heard the bell, even before food appeared.

22 Mar 2017

RUB researchers identify new rare muscle disorder

A new rare muscle disorder has been identified by researchers at Ruhr-Universität Bochum. This hereditary disease is caused by a defect in the BICD2 gene that manifests itself in altered cellular transport processes in skeletal muscle cells.

22 Mar 2017

FDA approves drug as add-on treatment for Parkinson's disease patients

The U.S. Food and Drug Administration today approved Xadago (safinamide) tablets as an add-on treatment for patients with Parkinson's disease who are currently taking levodopa/carbidopa and experiencing "off" episodes.

21 Mar 2017

Researchers identify sex-based differences in utilization, safety outcomes of CDT for treatment of DVT

Deep vein thrombosis (DVT) is a serious condition that occurs when a blood clot forms in a vein, often in the deep veins of the legs, thigh or pelvis. Those clots can break loose, travel to the lungs and block blood flow, causing a pulmonary embolism.

21 Mar 2017

Study: Treatment window for Fragile X syndrome likely remains open into maturity after childhood

Brain samples from humans show that the treatment window for Fragile X syndrome likely remains open well into maturity after childhood, when previous tests with mice indicated it might close, according to a new Drexel University-led study.

21 Mar 2017

New stenting tool found to be less painful and cheaper than current methods

A new tool for assessing the narrowing of the heart's arteries was found to be as effective as current methods and less painful for patients.

21 Mar 2017

Many Canadian family doctors still use manual devices to measure blood pressure, study shows

A study by researchers at the University of Montreal Hospital Research Centre (CRCHUM) shows that more than half of family doctors in Canada are still using manual devices to measure blood pressure, a dated technology that often leads to misdiagnosis.

20 Mar 2017

Linking RNA to autoimmune diseases

An interview with Dr. Chase Spurlock, CEO, discussing IQuity's research into IncRNAs and how they are linked to autoimmue diseases.

20 Mar 2017

New iFR technique for assessing clogged arteries reduces discomfort and adverse events

For patients experiencing angina (chest pain) or a heart attack, a new tool called instantaneous wave-free ratio (iFR) was equivalent to the currently-preferred tool, fractional flow reserve (FFR), in terms of incidence of major adverse events according to two studies presented at the American College of Cardiology's 66th Annual Scientific Session. The studies also showed iFR resulted in markedly less patient discomfort and reduced procedure-related adverse events compared to FFR.

20 Mar 2017

Novel synthetic HDL-C injection shows no benefit on arterial plaques

Injection of a novel form of synthetic high-density lipoprotein cholesterol (HDL-C), or good cholesterol, into the arteries of patients who had recently had a heart attack did not reduce the volume of fatty deposits, or plaque, in the arteries, compared with placebo injections, according to research presented at the American College of Cardiology's 66th Annual Scientific Session.

20 Mar 2017

Drosophila models help illuminate molecular mechanisms underlying nephrotic syndrome

The majority of genes associated with nephrotic syndrome (NS) in humans also play pivotal roles in Drosophila renal function, a conservation of function across species that validates transgenic flies as ideal pre-clinical models to improve understanding of human disease, a Children's National Health System research team reports in a recent issue of Human Molecular Genetics.

17 Mar 2017

High-resolution images of protein complex performing first step in genome-replication dance captured

It's a good thing we don't have to think about putting all the necessary pieces in place when one of our trillions of cells needs to duplicate its DNA and then divide to produce identical daughter cells.

17 Mar 2017

High levels of two biomarkers can predict risk for adverse cardiac events, research suggests

New research suggests that GlycA, a newly identified blood marker, and C-reactive protein both independently predict major adverse cardiac events, including heart failure and death. Patients who have high levels of both biomarkers are at especially high risk.

17 Mar 2017

Canadian scientists join international battle against Zika virus

The spread of the Zika virus, which can cause devastating birth defects, has become a pressing public health issue in many countries. To this day, there is no vaccine to prevent and no medicine to treat Zika virus infections.

16 Mar 2017

Study provides insights into genetic, neuronal circuit mechanisms linked to autism's impaired sociability

Researchers at Beth Israel Deaconess Medical Center have gained new insight into the genetic and neuronal circuit mechanisms that may contribute to impaired sociability in some forms of Autism Spectrum Disorder.

16 Mar 2017

Study explores clinical impact of delirium in patients with acute cardiac diseases

Delirium is associated with a five-fold increase in mortality in acute cardiac patients, according to research published today in European Heart Journal: Acute Cardiovascular Care. Delirium was common and affected over half of acute cardiac patients aged 85 years and older.

16 Mar 2017

Scientists create first model of anorexia nervosa using iPSCs derived from adolescent females

An international research team, led by scientists at University of California San Diego School of Medicine, has created the first cellular model of anorexia nervosa (AN), reprogramming induced pluripotent stem cells (iPSCs) derived from adolescent females with the eating disorder.

14 Mar 2017

Pre-existing immunity to dengue virus modulates T cell response to Zika infection

Although Zika and dengue are considered different virus "species," they are so closely related that the immune system treats Zika just like another version of dengue, report researchers at La Jolla Institute for Allergy and Immunology.

13 Mar 2017

Syndrome News and Research

Inner ear gene therapy holds promise for treating patients with hearing loss and dizziness

Study links gastrointestinal disturbances of GWI with changes in intestinal microbiota

UCLA study traces Pavlovian response to small cluster of brain cells

RUB researchers identify new rare muscle disorder

FDA approves drug as add-on treatment for Parkinson's disease patients

Researchers identify sex-based differences in utilization, safety outcomes of CDT for treatment of DVT

Study: Treatment window for Fragile X syndrome likely remains open into maturity after childhood

New stenting tool found to be less painful and cheaper than current methods

Many Canadian family doctors still use manual devices to measure blood pressure, study shows

Linking RNA to autoimmune diseases

New iFR technique for assessing clogged arteries reduces discomfort and adverse events

Novel synthetic HDL-C injection shows no benefit on arterial plaques

Drosophila models help illuminate molecular mechanisms underlying nephrotic syndrome

High-resolution images of protein complex performing first step in genome-replication dance captured

High levels of two biomarkers can predict risk for adverse cardiac events, research suggests

Canadian scientists join international battle against Zika virus

Study provides insights into genetic, neuronal circuit mechanisms linked to autism's impaired sociability

Study explores clinical impact of delirium in patients with acute cardiac diseases

Scientists create first model of anorexia nervosa using iPSCs derived from adolescent females

Pre-existing immunity to dengue virus modulates T cell response to Zika infection

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News