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Matricellular proteins may be key therapeutic targets for common ocular disorders

A special issue of Journal of Ocular Pharmacology and Therapeutics highlights the latest research on matricellular proteins, which play a critical role in inflammation and blood vessel formation in the eye and therefore making them key targets for new therapies to treat common ocular disorders such as glaucoma, dry eye disease, and age-related macular degeneration (AMD).

23 Sep 2015

S. Lawrence Zipursky to receive 2015 Louisa Gross Horwitz Prize from Columbia University

Columbia University will award the 2015 Louisa Gross Horwitz Prize to S. Lawrence Zipursky, PhD, for discovering a molecular identification system that helps neurons to navigate and wire the brain. Zipursky is a professor of biological chemistry at the University of California, Los Angeles and a Howard Hughes Medical Institute investigator.

23 Sep 2015

UCI scientists find potential biomarker for diagnosing certain forms of autism

By identifying a key signaling defect within a specific membrane structure in all cells, University of California, Irvine researchers believe, they have found both a possible reliable biomarker for diagnosing certain forms of autism and a potential therapeutic target.

22 Sep 2015

Researchers find novel connection between choroid plexus and complex regional pain syndrome

Aalto University neuroscientists, in collaboration with researchers at Helsinki University Hospital and Harvard Medical School, have found a novel connection between the size of the choroid plexus in the brain and complex regional pain syndrome (CRPS).

22 Sep 2015

Palatin Technologies reports net loss of $12.1 million for fourth quarter 2015

Palatin Technologies, Inc., a biopharmaceutical company developing targeted, receptor-specific peptide therapeutics for the treatment of diseases with significant unmet medical need and commercial potential, today announced results for its fourth quarter and fiscal year ended June 30, 2015.

21 Sep 2015

Hermansky-Pudlak syndrome can cause debilitating lung disease in Puerto Ricans

A hereditary condition called Hermansky-Pudlak syndrome (HPS) can cause bleeding problems, low vision, albinism and, in some patients, a debilitating lung disease.

21 Sep 2015

Study confirms pathogenic role of beta amyloid in dementia as seen in AD and Down syndrome

More than five million Americans are living with Alzheimer's disease (AD). Of them, 400,000 also have Down syndrome. Both groups have similar looking brains with higher levels of the protein beta amyloid.

18 Sep 2015

Researchers identify protein that regulates neuron growth

An international team of researchers, led by scientists at the National University of Singapore (NUS), has identified a protein that regulates the growth of neurons by transporting key metabolic enzymes to the tips of neural cells.

18 Sep 2015

Tolerability benefits with sunitinib schedule switch

Switching sunitinib treatment from a 4/2 to a modified 2/1 schedule can improve the tolerability profile for patients with metastatic renal cell carcinoma, say researchers.

17 Sep 2015

First-line TKI adverse event profile has no bearing on second-line RCC treatment choice

In metastatic renal cell carcinoma patients, there is no significant correlation between adverse event profiles of first- and second-line tyrosine kinase inhibitors, suggests a Japanese study.

17 Sep 2015

GENFIT develops reliable, non-invasive diagnostic tool for NASH patients

GENFIT, a biopharmaceutical company at the forefront of developing therapeutic and diagnostic solutions in metabolic and inflammatory diseases, that notably affect the liver or the gastrointestinal system, today announces the development of a new reliable and non-invasive diagnostic method, based on the measurement of a novel type of blood biomarker: small non-coding RNA, or miRNA.

16 Sep 2015

New whitepaper describes benefits of using OGT’s CytoSure Medical Research Exome Array in genetic research

Oxford Gene Technology, The Molecular Genetics Company, has been speaking to genetic scientists, Dr Tracey Lewis (Associated Regional and University Pathologists Laboratories) and Dr Emily Farrow (Children’s Mercy Hospital), in a new whitepaper entitled “Examining the Medical Exome”.

From Oxford Gene Technology 15 Sep 2015

Researchers discover new gene that could be a potential therapeutic target for muscle wasting

It is estimated that half of all cancer patients suffer from a muscle wasting syndrome called cachexia. Cancer cachexia impairs quality of life and response to therapy, which increases morbidity and mortality of cancer patients. Currently, there is no approved treatment for muscle wasting but a new study from the Research Institute of the McGill University Health Centre and University of Alberta could be a game changer for patients, improving both quality of life and longevity.

15 Sep 2015

Prolonged sitting time, reduced physical activity contribute to non-alcoholic fatty liver disease

Prolonged sitting time as well as reduced physical activity contribute to the prevalence of non-alcoholic fatty liver disease (NAFLD) in a study of middle-aged Koreans.

15 Sep 2015

ProPhase partners with Multi Health Systems to standardize electronic adaptations of PANSS

ProPhase LLC, a global provider of applied measurement expertise, is announcing its partnership with Multi Health Systems, a Canadian publisher of psychological assessments and healthcare outcomes, to optimize and standardize electronic adaptations of the Positive and Negative Syndrome Scale (PANSS).

14 Sep 2015

Study finds association between long sleep duration and high serum copper concentration

Persons sleeping less than 6 hours or more than 10 hours suffer from low-grade inflammation more often than persons sleeping 7-8 hours per night. This was observed in a University of Eastern Finland study focusing on the health and lifestyle habits among middle-aged men.

14 Sep 2015

New treatment protocol can improve outcomes for babies with neonatal abstinence syndrome

A new protocol to treat babies born in withdrawal from drugs can be used widely to improve outcomes for these babies. The protocol reduces length of stay and the duration of treatment with opioids that are used therapeutically to wean babies off of drugs.

14 Sep 2015

Diabetes drug 'suffocates' pancreatic cancer stem cells, new study finds

A new study shows that pancreatic cancer stem cells (PancSCs) are virtually addicted to oxygen-based metabolism, and could be "suffocated" with a drug already used to treat diabetes.

14 Sep 2015

New AGA guideline recommends colorectal cancer patients to undergo tumor test for Lynch syndrome

All colorectal cancer patients should undergo tumor testing to see if they carry Lynch syndrome, the most common inherited cause of colorectal cancer, according to a new guideline published in Gastroenterology, the official journal of the American Gastroenterological Association.

11 Sep 2015

BioDelivery Sciences and Endo present Phase 2 data on buprenorphine HCl buccal film in patients with chronic pain

Endo Pharmaceuticals Inc., a subsidiary of Endo International plc, and BioDelivery Sciences International, Inc. today presented data from a Phase 2 study for the investigational drug buprenorphine HCl buccal film utilizing BDSI’s patented BioErodible MucoAdhesive (BEMA) drug delivery technology.

11 Sep 2015

Syndrome News and Research

Matricellular proteins may be key therapeutic targets for common ocular disorders

S. Lawrence Zipursky to receive 2015 Louisa Gross Horwitz Prize from Columbia University

UCI scientists find potential biomarker for diagnosing certain forms of autism

Researchers find novel connection between choroid plexus and complex regional pain syndrome

Palatin Technologies reports net loss of $12.1 million for fourth quarter 2015

Hermansky-Pudlak syndrome can cause debilitating lung disease in Puerto Ricans

Study confirms pathogenic role of beta amyloid in dementia as seen in AD and Down syndrome

Researchers identify protein that regulates neuron growth

Tolerability benefits with sunitinib schedule switch

First-line TKI adverse event profile has no bearing on second-line RCC treatment choice

GENFIT develops reliable, non-invasive diagnostic tool for NASH patients

New whitepaper describes benefits of using OGT’s CytoSure Medical Research Exome Array in genetic research

Researchers discover new gene that could be a potential therapeutic target for muscle wasting

Prolonged sitting time, reduced physical activity contribute to non-alcoholic fatty liver disease

ProPhase partners with Multi Health Systems to standardize electronic adaptations of PANSS

Study finds association between long sleep duration and high serum copper concentration

New treatment protocol can improve outcomes for babies with neonatal abstinence syndrome

Diabetes drug 'suffocates' pancreatic cancer stem cells, new study finds

New AGA guideline recommends colorectal cancer patients to undergo tumor test for Lynch syndrome

BioDelivery Sciences and Endo present Phase 2 data on buprenorphine HCl buccal film in patients with chronic pain

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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