Syndrome News and Research

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Around 9.6% of women diagnosed with dry eye disease, treated with artificial tear eye drops

The symptoms of dry eye disease include the sensation of grit in the eye, frequently accompanied by itching, burning and visual disturbance. The causes are poorly understood.

3 Sep 2014

MEI Pharma completes patient enrollment in Pracinostat Phase II trial for treatment of MDS

MEI Pharma, Inc., an oncology company focused on the clinical development of novel therapies for cancer, announced today that it has completed enrollment in a randomized Phase II clinical trial of its lead investigational drug candidate Pracinostat in combination with azacitidine in patients with previously untreated intermediate-2 or high-risk myelodysplastic syndrome (MDS).

2 Sep 2014

Researchers reveal how alteration of single nucleotide could initiate fragile X syndrome

Researchers reveal how the alteration of a single nucleotide—the basic building block of DNA—could initiate fragile X syndrome, the most common inherited form of intellectual disability. The study appears in The Journal of Cell Biology.

2 Sep 2014

Darapladib drug fails to reduce risk of recurrent major coronary events

In patients who experienced an acute coronary syndrome (ACS) event (such as heart attack or unstable angina), use of the drug darapladib to inhibit the enzyme lipoprotein-associated phospholipase A2 (believed to play a role in the development of atherosclerosis) did not reduce the risk of recurrent major coronary events, according to a study published by JAMA.

1 Sep 2014

Study: Resistant hypertension increases risk of stroke in female and elderly patients

Resistant hypertension increases the risk of stroke by 35% in women and 20% in elderly Taiwanese patients, according to research presented at ESC Congress today by Dr Kuo-Yang Wang from Taiwan.

1 Sep 2014

Study suggests that energy drinks can cause heart problems

Energy drinks can cause heart problems according to research presented at ESC Congress 2014 today by Professor Milou-Daniel Drici from France.

1 Sep 2014

Comprehensive fitness and nutrition regimens may prevent bone and muscle deterioration

Being physically active may significantly improve musculoskeletal and overall health, and minimize or delay the effects of aging, according to a review of the latest research on senior athletes (ages 65 and up) appearing in the September issue of the Journal of the American Academy of Orthopaedic Surgeons (JAAOS).

30 Aug 2014

Plant-based medication after cardiac surgery shows mixed results in reducing complications

Administration of colchicine, a plant-based medication commonly used to treat gout, before and after cardiac surgery showed mixed results in reducing potential complications from this type of surgery, but it did increase the risk of gastrointestinal adverse effects, according to a study published by JAMA.

30 Aug 2014

New paper highlights ways to improve outcomes of Ebola virus infection

The largest-ever Ebola virus disease outbreak is ravaging West Africa, but with more personnel, basic monitoring, and supportive treatment, many of the sickest patients with Ebola virus disease do not need to die, note the authors of a new paper published ahead of print publication in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

30 Aug 2014

ESC Guidelines on diagnosis and treatment of aortic diseases published in European Heart Journal

The first comprehensive ESC Guidelines on aortic diseases are published today. They are presented at ESC Congress 2014 by Task Force Chairpersons Professor Raimund Erbel (Germany) and Professor Victor Aboyans (France).

30 Aug 2014

Researchers find method to expand blood stem cells used to treat cancer patients

A team of scientists from the University of Colorado School of Medicine has reported the breakthrough discovery of a process to expand production of stem cells used to treat cancer patients.

30 Aug 2014

UT Southwestern faculty awarded CPRIT grants to combat cancer

UT Southwestern Medical Center faculty have received 19 grants totaling more than $26 million from the Cancer Prevention and Research Institute of Texas to expand cancer screenings, investigate the effectiveness and viability for cancer therapies and radiation treatments, conduct research into cancer biology, and recruitment.

29 Aug 2014

Janssen, Bayer announce expansion of EXPLORER global cardiovascular research program for XARELTO

Janssen Research & Development, LLC and its development partner, Bayer HealthCare, announced today the expansion of the EXPLORER global cardiovascular research program for XARELTO (rivaroxaban) to include additional high-risk patient populations.

29 Aug 2014

Researchers reveal transmission rate of MERS coronavirus

The MERS coronavirus has caused disease outbreaks across the Arabian Peninsula and spread to Europe several times. The severe pneumonia virus has claimed the lives of several hundred people since its discovery in 2012.

29 Aug 2014

Changes in ADNP gene may provide further insight into causes of autism

A new study from Bradley Hospital has identified a genetic change in a recently identified autism-associated gene, which may provide further insight into the causes of autism. The study, now published online in the Journal of Medical Genetics, presents findings that likely represent a definitive clinical marker for some patients' developmental disabilities.

29 Aug 2014

Isis Pharmaceuticals begins ISIS-APOCIIIRx Phase 3 study in FCS patients

Isis Pharmaceuticals, Inc. announced the initiation of a Phase 3 study evaluating ISIS-APOCIIIRx in patients with familial chylomicronemia syndrome (FCS). FCS is a rare orphan disease, characterized by extremely high triglyceride levels, that affects an estimated 3,000 to 5,000 patients worldwide.

28 Aug 2014

Continuous positive airway pressure treatment effective for older patients with OSA

Continuous positive airway pressure is effective at treating sleep apnoea in older people, a new study has found.

27 Aug 2014

Obama to outline more veterans health care fixes

In a speech to the American Legion today, the president will announce new steps to improve veterans' access to mental health care and the transition in getting care from the Department of Defense to VA systems.

27 Aug 2014

Sorrento receives funding to advance immunotherapy targeting WISP1 for treatment of IPF

Sorrento Therapeutics, Inc. (NASDAQ: SRNE; Sorrento), a late-stage clinical oncology company developing new treatments for cancer and its associated pain, today announced that it has received funding to advance an immunotherapy targeting WNT1-Inducible Signaling Protein-1 (WISP1) for the potential treatment of IPF, which affects more than 100,000 Americans.

26 Aug 2014

Spanish scientists explore genetic basis of familial extreme longevity

In a recent report in Aging Cell, a multidisciplinary team of Spanish scientists, led by Tim Cash and Manuel Serrano at the Spanish National Cancer Research Centre, identify rare variants in the APOB gene in several families where exceptional longevity (>100 years of age) appears to cluster.

26 Aug 2014

Syndrome News and Research

Around 9.6% of women diagnosed with dry eye disease, treated with artificial tear eye drops

MEI Pharma completes patient enrollment in Pracinostat Phase II trial for treatment of MDS

Researchers reveal how alteration of single nucleotide could initiate fragile X syndrome

Darapladib drug fails to reduce risk of recurrent major coronary events

Study: Resistant hypertension increases risk of stroke in female and elderly patients

Study suggests that energy drinks can cause heart problems

Comprehensive fitness and nutrition regimens may prevent bone and muscle deterioration

Plant-based medication after cardiac surgery shows mixed results in reducing complications

New paper highlights ways to improve outcomes of Ebola virus infection

ESC Guidelines on diagnosis and treatment of aortic diseases published in European Heart Journal

Researchers find method to expand blood stem cells used to treat cancer patients

UT Southwestern faculty awarded CPRIT grants to combat cancer

Janssen, Bayer announce expansion of EXPLORER global cardiovascular research program for XARELTO

Researchers reveal transmission rate of MERS coronavirus

Changes in ADNP gene may provide further insight into causes of autism

Isis Pharmaceuticals begins ISIS-APOCIIIRx Phase 3 study in FCS patients

Continuous positive airway pressure treatment effective for older patients with OSA

Obama to outline more veterans health care fixes

Sorrento receives funding to advance immunotherapy targeting WISP1 for treatment of IPF

Spanish scientists explore genetic basis of familial extreme longevity

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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