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Penn State researchers investigate the factors influencing disease outcomes of virus spillover events

Why has the SARS-CoV-2 virus ravaged the global human population, but many other animal viruses haven't? Using nematode worms as a model, researchers at Penn State conducted a set of experiments to investigate the factors influencing the disease outcomes of virus spillover events.

30 Sep 2022

The compositional and functional diversity of the gut fungal microbiome

Researchers assessed the role of gut bacterial microbiome assembly and the gut mycobiome in relation to health, pathology, and clinical applications.

30 Sep 2022

DNA metagenomic analyses of clinical samples from Monkeypox virus-infected individuals

Researchers analyzed genomic sequences of MPXV obtained from 18 patients who contracted MPXV infection between June and July 2022.

30 Sep 2022

A novel method to identify spike stabilizing mutations for COVID-19 vaccine development

Researchers discuss a robust method to identify mutations that improve the expression and stabilize the conformation of the SARS-CoV-2 spike protein.

29 Sep 2022

Small larval fish provides insight into how the brain reacts when the temperature rises

Which organisms survive and which succumb when the climate changes? A small larval fish is providing surprising insight into how the brain reacts when the temperature rises.

29 Sep 2022

How a major COVID-19 outbreak occurred in a naïve and vaccinated population in Taiwan with a limited number of entry events

Researchers explored the SARS-CoV-2 genome using high-throughput genome sequencing to provide novel insights into how the novel SARS-CoV-2 Omicron BA.2.3.7 variant enters and spreads among the otherwise naïve Taiwanese population.

29 Sep 2022

New modeling technique can help better understand the development of rheumatoid arthritis

A new modeling technique can better predict how bones, cartilage, and cellular tissues will be affected by rheumatoid arthritis in small joints.

28 Sep 2022

UArizona researchers discover new protein that is responsible for controlling cell growth in yeasts

Like bacteria, yeasts are found everywhere, even in and around our bodies. And, as with bacteria, you can become infected by yeasts and become ill. Yeasts infect about 150 million people a year and kill about 1.7 million, especially those who are immunocompromised.

28 Sep 2022

Q-LAAD: a dynamic, cost-effective rapid antigen test for detection of SARS-CoV-2

Researchers developed a high-throughput, rapid antigen SARS-CoV-2 spike protein detection test using allonamers, a new type of aptamers that carry out allosteric regulation instead of catalytic activity.

28 Sep 2022

UVA researchers solve a decades-old mystery about how bacteria can move

University of Virginia School of Medicine researchers and their collaborators have solved a decades-old mystery about how E. coli and other bacteria are able to move.

27 Sep 2022

Natural product SSP derived from a Chinese herb may have broad antiviral activities against respiratory viral infections

A research team comprised of members of the School of Chinese Medicine, AIDS Institute, Department of Microbiology, School of Clinical Medicine and State Key Laboratory for Emerging Infectious Diseases, the LKS Faculty of Medicine, The University of Hong Kong (HKUMed) have discovered a natural product SSP derived from a Chinese herb Spatholobus Suberectus Dunnthat demonstrated broad antiviral activities against SARS-CoV-1, SARS-CoV-2, influenza, and HIV-1 as an entry blocker.

27 Sep 2022

Areas hospitable to Lassa virus spread may extend in the next several decades

In the study, which appeared on September 27 in Nature Communications, scientists analyzed decades of environmental data associated with Lassa virus outbreaks, revealing temperature, rainfall and the presence of pastureland areas as key factors contributing to viral transmission.

27 Sep 2022

Evolution of pathogens during vaccination programs

New research summarized the current understanding of pathogen evolution.

27 Sep 2022

Study finds remdesivir-resistant version of COVID-19 in renal transplant recipients

Recent studies have shown that patients with weakened immune systems—which enables the virus that causes COVID-19 to remain longer in the body, copy itself, and continually change—may enable the development of new, slightly different versions of the virus (variants).

26 Sep 2022

Study investigates long-range RNA-RNA interactions of SARS-CoV-2

Researchers explored RRIs [long-range ribonucleic acid (RNA)-RNA interactions] in SARS-CoV-2 variants of concern genomes to assess evolutionary changes in SARS-CoV-2.

26 Sep 2022

Omicron BA.1 breakthrough infection in vaccinated individuals recall memory B cells to confer immunity

In a new study, researchers followed up with individuals vaccinated with a COVID-19 vaccine based on the mRNA platform up to six months following Omicron BA.1 breakthrough infection to trace the evolution of their antibody immunity.

26 Sep 2022

How effective are live-attenuated SARS-CoV-2 vaccines?

Researchers opined on the use of live-attenuated whole virus vaccines as COVID-19 vaccines.

26 Sep 2022

Viruses exploit ability to sense the environment to maximize their infective yield

New UMBC-led research in Frontiers in Microbiology suggests that viruses are using information from their environment to "decide" when to sit tight inside their hosts and when to multiply and burst out, killing the host cell. The work has implications for antiviral drug development.

23 Sep 2022

Research reveals how carp virus uses a protein domain to inhibit host cell’s defense mechanisms

The team of Prof. Alain Vanderplasschen, virologist and immunologist at the University of Liège, has published an article in the journal Nucleic Acids Research, reporting ten years of research on how a carp virus has been using a protein domain called Zalpha (Zα) to inhibit the defense mechanisms of the host cell.

23 Sep 2022

How did the COVID-19 pandemic alter racial and ethnic disparities in mortality?

Researchers pursued evidence of all-cause mortality disparities during the COVID-19 pandemic in the United States, its temporal evolution, and whether this disparity persists.

22 Sep 2022

Evolution News and Research

Penn State researchers investigate the factors influencing disease outcomes of virus spillover events

The compositional and functional diversity of the gut fungal microbiome

DNA metagenomic analyses of clinical samples from Monkeypox virus-infected individuals

A novel method to identify spike stabilizing mutations for COVID-19 vaccine development

Small larval fish provides insight into how the brain reacts when the temperature rises

How a major COVID-19 outbreak occurred in a naïve and vaccinated population in Taiwan with a limited number of entry events

New modeling technique can help better understand the development of rheumatoid arthritis

UArizona researchers discover new protein that is responsible for controlling cell growth in yeasts

Q-LAAD: a dynamic, cost-effective rapid antigen test for detection of SARS-CoV-2

UVA researchers solve a decades-old mystery about how bacteria can move

Natural product SSP derived from a Chinese herb may have broad antiviral activities against respiratory viral infections

Areas hospitable to Lassa virus spread may extend in the next several decades

Evolution of pathogens during vaccination programs

Study finds remdesivir-resistant version of COVID-19 in renal transplant recipients

Study investigates long-range RNA-RNA interactions of SARS-CoV-2

Omicron BA.1 breakthrough infection in vaccinated individuals recall memory B cells to confer immunity

How effective are live-attenuated SARS-CoV-2 vaccines?

Viruses exploit ability to sense the environment to maximize their infective yield

Research reveals how carp virus uses a protein domain to inhibit host cell’s defense mechanisms

How did the COVID-19 pandemic alter racial and ethnic disparities in mortality?

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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