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Microvascular coronary dysfunction in women may be triggered by emotional stress, say researchers

Researchers at the Barbra Streisand Women's Heart Center at the Cedars-Sinai Heart Institute have found that emotional stressors - such as those provoking anger - may cause changes in the nervous system that controls heart rate and trigger a type of coronary artery dysfunction that occurs more frequently in women than men.

14 Mar 2014

Researcher detects higher rate of seizures among children with autism who were fed soy formula

A University of Wisconsin-Madison researcher has detected a higher rate of seizures among children with autism who were fed infant formula containing soy protein rather than milk protein.

14 Mar 2014

Discovery Laboratories reports net loss of $11.7 million for fourth quarter 2013

Discovery Laboratories, Inc., a specialty biotechnology company dedicated to advancing a new standard in respiratory critical care, today announced financial results for the fourth quarter ended December 31, 2013, as well as recent business updates.

13 Mar 2014

Knopp and NIAID collaborate to investigate eosinophil-lowering effects of dexpramipexole

Knopp Biosciences LLC today announced a second collaboration with the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), to investigate the eosinophil-lowering effects of the investigational drug dexpramipexole.

13 Mar 2014

Six in every ten serious heart defects in foetuses go undetected in ultrasound scans

Over six in every ten serious heart defects in foetuses go undetected in the ultrasound scans given to all pregnant women. According to research at Linköping University in Sweden, one reason why malformations are not found is obesity in the expectant mother.

13 Mar 2014

Two definitions of CMI symptoms should guide research and treatment of Gulf War veterans

Two existing definitions of chronic multisymptom illness (CMI) -- one by the Centers for Disease Control and Prevention and another from a study of Kansas Gulf War veterans -- should be used by the U.S. Department of Veterans Affairs to guide research and treatment of Gulf War veterans, says a new report from the Institute of Medicine.

13 Mar 2014

Viewpoints: 'Middlling news' on enrollment; 'secret mandate exemption;' Obama's surprising appearance between two ferns

By the beginning of the month, 4.2 million people had selected a plan. But that doesn't mean they have insurance. Reporters on a conference call asked about the number who had paid, and the administration's representatives said they don't know.

13 Mar 2014

Women who experience gestational diabetes may face increased risk of heart disease later in life

Women who experience gestational diabetes may face an increased risk of early heart disease later in life, even if they do not develop type 2 diabetes or metabolic syndrome subsequent to their pregnancy, according to a Kaiser Permanente study published today in the Journal of the American Heart Association.

13 Mar 2014

Patients with metabolic syndrome are more likely to have complications after total joint replacement

In a new study presented today at the 2014 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS), researchers found that total joint replacement patients with three or more metabolic syndrome risk factors were almost three times as likely to have complications within the first year after joint replacement.

11 Mar 2014

Nerve growth factor may be dynamic marker of OAB pathophysiology

Urine levels of nerve growth factor fluctuate in line with changes in bladder pathophysiology, a 5-year study of people with overactive bladder has found.

10 Mar 2014

Findings suggest that IBS is linked to detectable gut microbiota alterations

Irritable bowel syndrome (IBS) belongs to the most widespread diseases in Western countries, causing up to sixty per cent of the workload of gastrointestinal physicians. One of the most frequent symptoms of IBS is bloating, which reduces quality of life considerably as patients perceive it as particularly bothersome.

10 Mar 2014

Conditioned pain modulation decreases activity in human spinal cord, say researchers

Researchers have demonstrated that conditioned pain modulation (CPM), a measure of the brain's ability to regulate pain, decreases activity in the human spinal cord as visible via functional magnetic resonance imaging (fMRI).

10 Mar 2014

Edison Pharmaceuticals initiates Phase 2B/3 study of EPI-743 in children with Leigh syndrome

Edison Pharmaceuticals today announced the initiation of a phase 2B/3 study entitled, "A Phase 2B/3 Open-label Study of EPI-743 in Children with Leigh Syndrome" to be conducted in conjunction with Dainippon Sumitomo Pharma Co, Ltd.

10 Mar 2014

Mutations in gene associated with leukaemia may affect growth, intellectual development in children

Mutations in a gene associated with leukaemia cause a newly described condition that affects growth and intellectual development in children, new research reports.

10 Mar 2014

Treating long wait-times dictate long-term success of spinal cord stimulation therapy

Success rates soared to 75% for patients who waited less than 2 years for a spinal cord stimulator (SCS) implant, compared with 15% for patients whose implants happened 20 years after the onset of pain, according to a retrospective analysis.

7 Mar 2014

Researchers examine association between diabetes and obesity

It's by now well established that obesity is a major risk factor for diabetes. But what exactly is it about extra body fat that leads to insulin resistance and blood glucose elevation, the hallmarks of diabetes?

7 Mar 2014

Community care helps schizophrenia patients in resource-poor settings

Collaborative care delivered by community health workers can improve outcomes among patients with schizophrenia receiving facility-based case in resource-poor settings, shows a study in The Lancet.

6 Mar 2014

Small-molecule drug effective in protecting nonhuman primates from lethal Marburg virus

For the first time, scientists have demonstrated the effectiveness of a small-molecule drug in protecting nonhuman primates from the lethal Marburg virus. Their work, published online in the journal Nature, is the result of a continuing collaboration between Army scientists and industry partners that also shows promise for treating a broad range of other viral diseases.

5 Mar 2014

Long-term risks of deep vein thrombosis

Deep vein thrombosis (DVT) often brings with it the risk of post-thrombotic syndrome (PTS), an under-recognized but serious complication that often causes long-term disability for patients. During March's DVT Awareness Month, the Society of Interventional Radiology wants to help patients and family members to better understand the long-term risks of DVT.

5 Mar 2014

Researchers develop adjuvant which enhances effect of virus transduction

Lentiviruses, which belong to the family of retroviruses, are used as vectors to exchange genetic material in cells and can be used to replace a defective gene as defined by gene therapy.

5 Mar 2014

Syndrome News and Research

Microvascular coronary dysfunction in women may be triggered by emotional stress, say researchers

Researcher detects higher rate of seizures among children with autism who were fed soy formula

Discovery Laboratories reports net loss of $11.7 million for fourth quarter 2013

Knopp and NIAID collaborate to investigate eosinophil-lowering effects of dexpramipexole

Six in every ten serious heart defects in foetuses go undetected in ultrasound scans

Two definitions of CMI symptoms should guide research and treatment of Gulf War veterans

Viewpoints: 'Middlling news' on enrollment; 'secret mandate exemption;' Obama's surprising appearance between two ferns

Women who experience gestational diabetes may face increased risk of heart disease later in life

Patients with metabolic syndrome are more likely to have complications after total joint replacement

Nerve growth factor may be dynamic marker of OAB pathophysiology

Findings suggest that IBS is linked to detectable gut microbiota alterations

Conditioned pain modulation decreases activity in human spinal cord, say researchers

Edison Pharmaceuticals initiates Phase 2B/3 study of EPI-743 in children with Leigh syndrome

Mutations in gene associated with leukaemia may affect growth, intellectual development in children

Treating long wait-times dictate long-term success of spinal cord stimulation therapy

Researchers examine association between diabetes and obesity

Community care helps schizophrenia patients in resource-poor settings

Small-molecule drug effective in protecting nonhuman primates from lethal Marburg virus

Long-term risks of deep vein thrombosis

Researchers develop adjuvant which enhances effect of virus transduction

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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