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Chicken eggs can provide better understanding of human birth defects

Clemson University researchers found that chicken eggs can provide a better understanding of human birth defects. Susan Chapman, associate professor in Clemson's College of Agriculture, Forestry and Life Sciences, received a South Carolina IDeA Networks of Biomedical Research Excellence award that allowed researchers to identify two regions in the chicken genome that are associated with congenital deafness and spine deformities in humans.

26 Nov 2013

Sacral neuromodulation stands test of time in LUTD

Follow-up of patients at a Belgian institution reveals that sacral neuromodulation is effective for the treatment of lower urinary tract dysfunction over the long term, but often requires reintervention.

From Medtronic 25 Nov 2013

Scientists use RNAi technology to reveal genes responsible for treating Parkinson's disease

Scientists at the National Institutes of Health have used RNA interference (RNAi) technology to reveal dozens of genes which may represent new therapeutic targets for treating Parkinson's disease. The findings also may be relevant to several diseases caused by damage to mitochondria, the biological power plants found in cells throughout the body.

24 Nov 2013

NEXAVAR tablets receive FDA approval for treatment of patients with thyroid cancer

Bayer HealthCare and Onyx Pharmaceuticals, Inc., an Amgen subsidiary, today announced that the U.S. Food and Drug Administration has approved a supplemental New Drug Application for the oral multi-kinase inhibitor NEXAVAR (sorafenib) tablets for the treatment of patients with locally recurrent or metastatic, progressive, differentiated thyroid carcinoma refractory to radioactive iodine treatment.

23 Nov 2013

DNA vaccine demonstrates potential to prevent and treat deadly MERS coronavirus

Inovio Pharmaceuticals, Inc. announced today that preclinical testing of a DNA synthetic vaccine for the virulent Middle East Respiratory Syndrome coronavirus (MERS) induced robust and durable immune responses, demonstrating the potential for a SynCon DNA vaccine to prevent and treat this deadly virus.

20 Nov 2013

Findings underscore importance of obesity prevention and nutrition in addressing metabolic syndrome

Data reported by the Hearts Beat Back: The Heart of New Ulm Project reinforce the positive influence of lifestyle factors in mitigating risks that potentially increase the likelihood of heart disease and other health problems. Findings based on 1,059 residents of New Ulm, Minn, underscore the importance of obesity prevention and nutrition, specifically eating more fruits and vegetables, in addressing metabolic syndrome, a common precursor to cardiovascular disease.

20 Nov 2013

Study links health risks later in life to weight status in adolescence

From abnormal kidney function to difficulty walking and diabetes, severely obese adults who were obese as teenagers have greater risk of developing numerous harmful health conditions.

20 Nov 2013

NSU researchers selected to participate in DoD Gulf War Illness Research Program Consortium

Nova Southeastern University President and CEO George L. Hanbury II, Ph.D., recently announced that a NSU research team led by Mariana Morris, Ph.D., and Nancy Klimas, M.D., was selected by the U.S. Department of Defense as one of two DoD Gulf War Illness Research Program Consortium awardees.

20 Nov 2013

Cerebral basis for positive psychosis symptoms pinpointed

Altered activation in the secondary somatosensory cortex during sensorimotor experiences may underlie the flawed judgments resulting in positive schizophrenia symptoms, research suggests.

19 Nov 2013

Study finds patients treated with varespladib drug more likely to experience cardiovascular events

Patients with acute coronary syndrome who were treated with the experimental drug varespladib were more likely to experience additional cardiovascular events - including sudden death, heart attack and stroke - than those treated with placebo, according to research from the Cleveland Clinic Coordinating Center for Clinical Research (C5Research).

19 Nov 2013

Philipp E. Scherer honored with 15th Naomi Berrie Award for Outstanding Research in Diabetes

Columbia University Medical Center has honored Philipp E. Scherer, PhD, with the 15th Naomi Berrie Award for Outstanding Research in Diabetes, for his work that helped usher in a new understanding of fat and its role in diabetes and other metabolic diseases. His discovery of adiponectin, a hormone produced by fat, helped transform the scientific concept of fat as an inert storage depot to one of it as an endocrine "organ" that exerts control over the brain, muscles, and other organs. The award, given annually by CUMC's Naomi Berrie Diabetes Center, is Columbia's top honor for excellence in diabetes research.

19 Nov 2013

Patients better adhere to medication regimens following hospitalization for acute coronary syndrome

Patients better adhered to their medication regimens in the year following hospitalization for acute coronary syndrome when they were part of a program that included personalized attention from a pharmacist compared with usual care, according to a study by P. Michael Ho, M.D., Ph.D., of the Denver VA Medical Center, and colleagues.

19 Nov 2013

Kiadis reports successful Phase II enrollment for CR-AIR-007 ATIR blood cancer treatment study

Kiadis Pharma B.V., a clinical stage biopharmaceutical company developing treatments for blood cancers, today announces the successful Phase II enrollment of approximately ten patients of whom the majority have already been transplanted and received ATIR™. Kiadis Pharma's lead program, ATIR™, is a cell-based product designed to enable stem cell transplantations from partially mismatched (haploidentical) family donors for blood cancer patients who do not have a standard of care stem cell donor available. Topline data from the trial (CR-AIR-007) is expected in the first half of 2014.

18 Nov 2013

Scientists describe interplay of four molecules that trigger, govern antibody production in immune cells

Australian scientists have described an exquisitely balanced interplay of four molecules that trigger and govern antibody production in immune cells. As well as being an important basic science discovery, it helps explain why people with mutations in any one of the associated genes cannot fight infection effectively, and develop rare and crippling immunodeficiency disorders.

18 Nov 2013

Residents of major cities with high pollution levels have increased risk of dry eye syndrome

Residents of major cities with high levels of air pollution have an increased risk of dry eye syndrome, according to a study presented at the world's largest ophthalmic conference, the 117th Annual Meeting of the American Academy of Ophthalmology, in New Orleans.

17 Nov 2013

E-Rare funding recommended for European young investigators network for Usher syndrome

Based on a ranking list that was established by the EU Scientific Evaluation Committee, the E-Rare funding bodies recommended the European young investigators network for Usher syndrome coordinated by Dr. Kerstin Nagel-Wolfrum from Johannes Gutenberg University Mainz for funding. Out of 82 submitted projects, EUR-USH was among the 11 excellent scientific projects that were chosen after a competitive two-step scientific evaluation by peers. In October 2013, researchers held their kick-off meeting in Nijmegen, the Netherlands.

16 Nov 2013

Cardiovascular Institute researchers to showcase 22 abstracts at upcoming AHA Scientific Sessions

Researchers from the Cardiovascular Institute at Rhode Island, The Miriam and Newport hospitals will present 22 abstracts, both poster and oral presentations, at the upcoming American Heart Association Scientific Sessions, to be held in Dallas November 16-20, 2013. Scientific Sessions is the foremost cardiovascular research meeting in the U.S., with more than 18,000 cardiovascular experts from more than 105 countries in attendance.

16 Nov 2013

$23.8M NIH grant supports multi-center, multidisciplinary study on deadly bleeding syndrome

A new five-year, $23.8 million National Institutes of Health (NIH) grant will support a multi-center, multidisciplinary study on a deadly bleeding syndrome - called coagulopathy - that occurs without warning in some trauma patients.

16 Nov 2013

Researchers identify gene responsible for Warburg Micro syndrome

A collaborative team of researchers led by researchers at the Medical College of Wisconsin and the University of Edinburgh has identified a gene responsible for Warburg Micro syndrome, a rare genetic disease characterized by eye, brain and endocrine abnormalities. Patients with Warburg Micro syndrome are severely physically and mentally challenged, unable to learn how to walk or speak and become blind and paralyzed from an early age.

15 Nov 2013

Research sheds light on how protein keeps people organized by promoting orderly skeletal growth

Most people think that their planners or their iPhones keep them organized, when proteins such as liver kinase b1 (Lkb1) actually have a lot more to do with it. New research from postdoctoral fellow Lick Lai in the lab of USC scientist Andy McMahon published in Proceedings of the National Academy of Sciences (PNAS) sheds light on how this important protein keeps people organized on a basic level by promoting orderly skeletal growth and preventing skeletal tumors.

15 Nov 2013

Syndrome News and Research

Chicken eggs can provide better understanding of human birth defects

Sacral neuromodulation stands test of time in LUTD

Scientists use RNAi technology to reveal genes responsible for treating Parkinson's disease

NEXAVAR tablets receive FDA approval for treatment of patients with thyroid cancer

DNA vaccine demonstrates potential to prevent and treat deadly MERS coronavirus

Findings underscore importance of obesity prevention and nutrition in addressing metabolic syndrome

Study links health risks later in life to weight status in adolescence

NSU researchers selected to participate in DoD Gulf War Illness Research Program Consortium

Cerebral basis for positive psychosis symptoms pinpointed

Study finds patients treated with varespladib drug more likely to experience cardiovascular events

Philipp E. Scherer honored with 15th Naomi Berrie Award for Outstanding Research in Diabetes

Patients better adhere to medication regimens following hospitalization for acute coronary syndrome

Kiadis reports successful Phase II enrollment for CR-AIR-007 ATIR blood cancer treatment study

Scientists describe interplay of four molecules that trigger, govern antibody production in immune cells

Residents of major cities with high pollution levels have increased risk of dry eye syndrome

E-Rare funding recommended for European young investigators network for Usher syndrome

Cardiovascular Institute researchers to showcase 22 abstracts at upcoming AHA Scientific Sessions

$23.8M NIH grant supports multi-center, multidisciplinary study on deadly bleeding syndrome

Researchers identify gene responsible for Warburg Micro syndrome

Research sheds light on how protein keeps people organized by promoting orderly skeletal growth

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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