Syndrome News and Research

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High-intensity exercise protective against coronary heart disease

High-intensity exercise is shown to be protective against coronary heart disease and is well known as a popular and time-saving approach to getting fit. But what about people who already have heart disease? Previously, these patients were told to exercise, but only at a moderate intensity to protect their hearts. More recently, however, researchers have found that high-intensity exercise is very beneficial for these patients.

21 Sep 2013

Higher calorie diets produce twice rate of weight gain for adolescents hospitalized with anorexia

Higher calorie diets produce twice the rate of weight gain compared to the lower calorie diets that currently are recommended for adolescents hospitalized with anorexia nervosa, according to a study by researchers at UCSF Benioff Children-s Hospital.

21 Sep 2013

Antibody that binds, neutralizes HIV likely also targets the body's own self proteins

Researchers at The Scripps Research Institute discovered that an antibody that binds and neutralizes HIV likely also targets the body's own "self" proteins. This finding could complicate the development of HIV vaccines designed to elicit this protective antibody, called 4E10, and others like it, as doing so might be dangerous or inefficient.

20 Sep 2013

Vera and Paul Guerin Family Congenital Heart Program to be established in Cedars-Sinai Heart Institute

In an effort to lengthen the life span and improve the quality of life for those born with heart defects, longtime Cedars-Sinai supporters Vera and Paul Guerin have donated $10 million to establish the Vera and Paul Guerin Family Congenital Heart Program in the Cedars-Sinai Heart Institute.

20 Sep 2013

Orbeshield Earns Soligenix Up To $26.3M From BARDA

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19 Sep 2013

BARDA Exercises $6M Option For Aeolus' Acute Radiation Syndrome Drug

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19 Sep 2013

SHBG protein indicates risk of type 2 diabetes and metabolic syndrome years in advance

Over the last decade researchers have amassed increasing evidence that relatively low levels of a protein called sex hormone binding globulin (SHBG) can indicate an elevated risk of type 2 diabetes and metabolic syndrome years in advance.

19 Sep 2013

Researchers identify the way FMRP contributes to progression of breast cancer

A research team led by scientists from VIB/KU Leuven, Belgium, and the University of Rome Tor Vergata, Italy, in collaboration with several research centers and hospitals in Italy, the United Kingdom and, Belgium, has identified the way Fragile X Mental Retardation Protein or FMRP contributes to the progression of breast cancer.

18 Sep 2013

Children with 22q11.2 deletion syndrome may often be misdiagnosed to have autism

Children with a genetic disorder called 22q11.2 deletion syndrome, who frequently are believed to also have autism, often may be misidentified because the social impairments associated with their developmental delay may mimic the features of autism, a study by researchers with the UC Davis MIND Institute suggests.

18 Sep 2013

Researchers reveal mechanisms that connect Mfn2 protein to endoplasmic reticulum stress

Each cell in an organism has a sensor that measures the health of its "internal" environment. This "alarm" is found in the endoplasmic reticulum, which is able to sense cellular stress and trigger either rescue responses or the death of the cell.

18 Sep 2013

NHCS researchers discover potential cure for long QT syndrome 2

The National Heart Centre Singapore research team has successfully and completely reversed the effects of the hERG (human ether-a-go-go-related gene) mutation in long QT syndrome 2 in patient-specific heart cells, scoring a world's first.

18 Sep 2013

Obese men who binge are more likely to have elevated cholesterol, high blood pressure

Binge eating is a problem affecting both men and women, however obese men who binge are more likely than their female counterparts to have elevated cholesterol and high blood pressure, finds a new study in General Hospital Psychiatry.

18 Sep 2013

Women with acute coronary syndrome less likely to have chest pain than men

A higher proportion of women than men 55 years and younger did not have chest pain in acute coronary syndromes (ACS, such as heart attacks or unstable angina), although chest pain was the most common symptom for both sexes, according to a study published by JAMA Internal Medicine, a JAMA Network publication.

17 Sep 2013

First generic version of Xeloda gets FDA approval for breast and colorectal cancers

The U.S. Food and Drug Administration today approved the first generic version of Xeloda (capecitabine), an oral chemotherapy pill used to treat cancer of the colon or rectum (colorectal cancer) that has spread to other parts of the body (metastatic), and metastatic breast cancer.

17 Sep 2013

Hyperthyroidism sounds urinary problem alarm

Physicians should be alert to urinary problems in women with hyperthyroidism, say researchers who found an association between the endocrine disorder and bladder pain syndrome/interstitial cystitis.

16 Sep 2013

FDA grants orphan drug designation to Soligenix’s SGX94 for treatment of Acute Radiation Syndrome

Soligenix, Inc., a clinical stage biopharmaceutical company focused on developing products to treat inflammatory diseases and biodefense countermeasures where there remains an unmet medical need, announced today that the Office of Orphan Products Development of the US Food and Drug Administration (FDA) has granted orphan drug designation to the active ingredient SGX94 for the treatment of acute radiation syndrome (ARS).

16 Sep 2013

New neuroimaging and bioinformatics tools for predicting psychotic disorders

A new EU project, METSY, develops and applies neuroimaging and bioinformatics tools to study how lipid metabolism is connected to psychotic disorders and metabolic co-morbidities such as metabolic syndrome and diabetes.

16 Sep 2013

Pew honors creative work on coronaviruses with biomedical researcher award

Cell biologist Carolyn Machamer, Ph.D is The Pew Charitable Trusts' biomedical researcher of the month for her creative work on coronaviruses. Specifically, Machamer studies how the family of viruses uses a host cell's machinery against it.

13 Sep 2013

Genetic deficiency in autism linked to specific molecular and cellular consequences

Brown University researchers have traced a genetic deficiency implicated in autism in humans to specific molecular and cellular consequences that cause clear deficits in mice in how well neurons can grow the intricate branches that allow them to connect to brain circuits. The researchers also show in their study (online Sep. 12, 2013, in Neuron) that they could restore proper neuronal growth by compensating for the errant molecular mechanisms they identified.

13 Sep 2013

Researchers develop new ways of preventing septic shock

The body's immune system is set up much like a home security system; it has sensors on the outside of cells that act like motion detectors — floodlights — that click on when there's an intruder rustling in the bushes, bacteria that seem suspect.

13 Sep 2013

Syndrome News and Research

High-intensity exercise protective against coronary heart disease

Higher calorie diets produce twice rate of weight gain for adolescents hospitalized with anorexia

Antibody that binds, neutralizes HIV likely also targets the body's own self proteins

Vera and Paul Guerin Family Congenital Heart Program to be established in Cedars-Sinai Heart Institute

Orbeshield Earns Soligenix Up To $26.3M From BARDA

BARDA Exercises $6M Option For Aeolus' Acute Radiation Syndrome Drug

SHBG protein indicates risk of type 2 diabetes and metabolic syndrome years in advance

Researchers identify the way FMRP contributes to progression of breast cancer

Children with 22q11.2 deletion syndrome may often be misdiagnosed to have autism

Researchers reveal mechanisms that connect Mfn2 protein to endoplasmic reticulum stress

NHCS researchers discover potential cure for long QT syndrome 2

Obese men who binge are more likely to have elevated cholesterol, high blood pressure

Women with acute coronary syndrome less likely to have chest pain than men

First generic version of Xeloda gets FDA approval for breast and colorectal cancers

Hyperthyroidism sounds urinary problem alarm

FDA grants orphan drug designation to Soligenix’s SGX94 for treatment of Acute Radiation Syndrome

New neuroimaging and bioinformatics tools for predicting psychotic disorders

Pew honors creative work on coronaviruses with biomedical researcher award

Genetic deficiency in autism linked to specific molecular and cellular consequences

Researchers develop new ways of preventing septic shock

Industry Focus eBook - Cell biology (5th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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