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Four new pre-clinical drug development projects at NIH develop treatment for rare disease

Four new pre-clinical drug development projects at the National Institutes of Health will target a form of blindness and diseases characterized by cardiac problems. The projects were selected for their potential to treat specific rare diseases and to help scientists uncover new information that can be shared with other researchers.

13 Sep 2013

Helper T cells important for AIDS vaccine development

A major new finding that will significantly advance efforts to create the world's first antibody-based AIDS vaccine was published today by researchers from the La Jolla Institute for Allergy and Immunology.

13 Sep 2013

Research: Treatment with antioxidants may help reduce behavioral issues linked to NF1

New research in mouse models suggests that treatment with antioxidants may help reduce behavioral issues linked to the genetic nervous system disorder Neurofibromatosis 1 (NF1) and an associated condition called Costello syndrome.

12 Sep 2013

Care Pathways and Outcomes Study provides vital information about young children in care

The findings from one of the most comprehensive long-term studies ever undertaken into children in care will be revealed at Queen's University Belfast today (Wednesday 11 September).

12 Sep 2013

Hormonal disorder causes irregular periods among teenage girls

While irregular periods are common among teenage girls, an underlying hormonal disorder may be to blame if this problem persists.

12 Sep 2013

Electroacupuncture treatment improves visceral hypersensitivity in irritable bowel syndrome

Irritable bowel syndrome patients extensively suffer from chronic visceral hypersensitivity, with involvement of all levels of the brain-gut axis, as well as various neurotransmitters.

12 Sep 2013

FDA takes steps to restrict the use of pain meds

The Food and Drug Administration will require a class-wide label change for long-acting opioids aimed at limiting use of these drugs to patients with severe, refractory pain.

12 Sep 2013

Kiadis five-year follow-up phase I/II clinical study confirms long-term safety, efficacy of ATIR

Kiadis Pharma B.V., a clinical stage biopharmaceutical company developing treatments for blood cancers, announced today that the five-year follow-up of patients with high-risk malignancies from its Phase I/II clinical study confirms long-term safety and efficacy of ATIR™ over a broad dose range.

12 Sep 2013

New technique provides better understanding of factors causing Smith-Lemli-Opitz Syndrome

The first proteomic analysis of an animal model of a rare, sometimes deadly birth defect, Smith-Lemli-Opitz Syndrome (SLOS), has revealed that the molecular mechanisms that cause it are more complex than previously understood.

12 Sep 2013

Rutgers scientist finds important clue on origins of multiple sclerosis

The search for the cause of multiple sclerosis, a debilitating disease that affects up to a half million people in the United States, has confounded researchers and medical professionals for generations. But Steven Schutzer, a physician and scientist at Rutgers New Jersey Medical School, has now found an important clue why progress has been slow - it appears that most research on the origins of MS has focused on the wrong part of the brain.

11 Sep 2013

Combination drug does not improve survival in patients with severe alcoholic hepatitis

Four weeks of treatment with a combination of the drug pentoxifylline and the corticosteroid prednisolone did not improve 6-month survival compared with prednisolone alone in 270 patients with severe alcoholic hepatitis, according to a study in the September 11 issue of JAMA.

11 Sep 2013

Safety labeling changes announced for extended-release and long-acting opioid analgesics

The U.S. Food and Drug Administration today announced class-wide safety labeling changes and new postmarket study requirements for all extended-release and long-acting opioid analgesics intended to treat pain.

11 Sep 2013

Interferon-alpha 2b and ribavirin treatment may be effective for MERS-CoV infection

Treatment with two common drugs reduced viral replication and lung damage when given to monkeys infected with the virus that causes Middle East Respiratory Syndrome. The condition is deadly pneumonia that has killed more than 100 people, primarily in the Middle East.

10 Sep 2013

Weill Cornell Medical College gets $100M gift to launch Driving Discoveries, Changing Lives campaign

Weill Cornell Medical College announced today that it has received a $100 million gift from longtime benefactors Joan and Sanford I. Weill and the Weill Family Foundation to launch the Medical College's $300 million Driving Discoveries, Changing Lives campaign dedicated to using the most advanced scientific approaches to rapidly translate research breakthroughs into innovative treatments and therapies for patients.

10 Sep 2013

Beverage coaster campaign reminds pregnant women on dangerous effects of alcohol

Before taking a sip of alcohol at nearly a dozen local bars and restaurants, San Diegans will be reminded of the dangers of mixing alcohol and pregnancy thanks to a beverage coaster campaign led by the new Southern California chapter of the National Organization on Fetal Alcohol Syndrome (SoCal NOFAS), in partnership with University of California, San Diego School of Medicine.

10 Sep 2013

Combination of 2 antiviral drugs improves outcome in monkey model of MERS-CoV infection

National Institutes of Health (NIH) scientists report that a combination of two licensed antiviral drugs reduces virus replication and improves clinical outcome in a recently developed monkey model of Middle East respiratory syndrome coronavirus (MERS-CoV) infection.

10 Sep 2013

Scientists develop strain of MERS-CoV that can be used as vaccine against disease

Scientists have developed a strain of the Middle East respiratory syndrome coronavirus (MERS-CoV) that could be used as a vaccine against the disease, according to a study to be published in mBio-, the online open-access journal of the American Society for Microbiology.

10 Sep 2013

Emerging H7N9 virus has potential to cause a pandemic

A new study has found that a novel avian-origin H7N9 influenza A virus, which has recently emerged in humans, attaches moderately or abundantly to the epithelium of both the upper and lower respiratory tracts.

10 Sep 2013

Mental illness increases risk of physical illness by 10 times in men and women

Men were more likely to develop a physical illness than women during a 10-year period studied by researchers at St. Michael's Hospital.

10 Sep 2013

Scientists find link between early-onset Parkinson's and 22q11.2 deletion syndrome

Scientists at the Centre for Addiction and Mental Health (CAMH) and University Health Network (UHN) have found a new link between early-onset Parkinson's disease and a piece of DNA missing from chromosome 22. The findings help shed new light on the molecular changes that lead to Parkinson's disease.

10 Sep 2013

Syndrome News and Research

Four new pre-clinical drug development projects at NIH develop treatment for rare disease

Helper T cells important for AIDS vaccine development

Research: Treatment with antioxidants may help reduce behavioral issues linked to NF1

Care Pathways and Outcomes Study provides vital information about young children in care

Hormonal disorder causes irregular periods among teenage girls

Electroacupuncture treatment improves visceral hypersensitivity in irritable bowel syndrome

FDA takes steps to restrict the use of pain meds

Kiadis five-year follow-up phase I/II clinical study confirms long-term safety, efficacy of ATIR

New technique provides better understanding of factors causing Smith-Lemli-Opitz Syndrome

Rutgers scientist finds important clue on origins of multiple sclerosis

Combination drug does not improve survival in patients with severe alcoholic hepatitis

Safety labeling changes announced for extended-release and long-acting opioid analgesics

Interferon-alpha 2b and ribavirin treatment may be effective for MERS-CoV infection

Weill Cornell Medical College gets $100M gift to launch Driving Discoveries, Changing Lives campaign

Beverage coaster campaign reminds pregnant women on dangerous effects of alcohol

Combination of 2 antiviral drugs improves outcome in monkey model of MERS-CoV infection

Scientists develop strain of MERS-CoV that can be used as vaccine against disease

Emerging H7N9 virus has potential to cause a pandemic

Mental illness increases risk of physical illness by 10 times in men and women

Scientists find link between early-onset Parkinson's and 22q11.2 deletion syndrome

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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