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Weekend reading: Mental illness stigma, health insurance mazes and female libido

Linneah sat at a desk at the Center for Sexual Medicine at Sheppard Pratt in the suburbs of Baltimore and filled out a questionnaire. She read briskly, making swift checks beside her selected answers, and when she was finished, she handed the pages across the desk to Martina Miller, who gave her a round of pills.

24 May 2013

Wisconsin scientists synthesize potent compounds to curb bacteria that cause staph infections

In an age when microbial pathogens are growing increasingly resistant to the conventional antibiotics used to tamp down infection, a team of Wisconsin scientists has synthesized a potent new class of compounds capable of curbing the bacteria that cause staph infections.

24 May 2013

Early adenotonsillectomy can improve behavior and sleep apnea symptoms in children

Adenotonsillectomy, or the removal of the adenoids and tonsils, is performed 500,000 times a year in the United States, often as a treatment for children with obstructive sleep apnea.

22 May 2013

Genetic risk factor for pulmonary fibrosis can be used to identify individuals at risk for lung disease

A paper recently published in the New England Journal of Medicine and co-written by physicians and scientists at the University of Colorado School of Medicine finds that an important genetic risk factor for pulmonary fibrosis can be used to identify individuals at risk for this deadly lung disease.

22 May 2013

Caltech biologists show that microRNA-146a protects stem cells during inflammation

When infections occur in the body, stem cells in the blood often jump into action by multiplying and differentiating into mature immune cells that can fight off illness. But repeated infections and inflammation can deplete these cell populations, potentially leading to the development of serious blood conditions such as cancer.

22 May 2013

Study: 3/4 women experience constipation and other bowel disorders during their pregnancies

Nearly three out of four pregnant women experience constipation, diarrhea or other bowel disorders during their pregnancies, a Loyola University Medical Center study has found.

21 May 2013

Researchers develop new mouse model to discover gene pathways that drive MPNST

University of Minnesota Medical School researchers from the Masonic Cancer Center, University of Minnesota, in partnership with the University's Brain Tumor Program, have developed a new mouse model of malignant peripheral nerve sheath tumors that allow them to discover new genes and gene pathways driving this type of cancer.

21 May 2013

Research explores pharmaceutical advances for IBS, hepatitis C

Research presented at Digestive Disease Week explores pharmaceutical advances for treating irritable bowel syndrome with diarrhea and hepatitis C.

21 May 2013

Researchers identify novel biomarkers for predicting mortality in ICU patients

A metabolic profile of intensive care unit patients based on biomarkers of four metabolites can be used to accurately predict mortality, according to a new study.

21 May 2013

New breakthrough in progeria treatment

Pharmaceuticals that inhibit a specific enzyme may be useful in treating progeria, or accelerated aging in children. A new study performed at the Sahlgrenska Academy, University of Gothenburg, Sweden, indicates that the development of progeria in mice was inhibited upon reducing the production of this enzyme.

21 May 2013

Neupro reduces PLMS and total NSBP elevations in patients with RLS, study finds

UCB today announced data from a double-blind, placebo-controlled study that found that Neupro (Rotigotine Transdermal System) reduced total nocturnal systolic blood pressure elevations associated with periodic limb movements during sleep and total PLMS in patients with idiopathic moderate-to-severe Restless Legs Syndrome/Willis-Ekbom disease.

18 May 2013

Study examines self-management support in primary care

The processes to allow people to self-manage their own illness are not being used appropriately by health professionals to the benefit of their patients, new research suggests.

18 May 2013

UCSF researchers create first functioning human thymus tissue from embryonic stem cells

Raising hopes for cell-based therapies, UC San Francisco researchers have created the first functioning human thymus tissue from embryonic stem cells, in the laboratory. The researchers showed that, in mice, the tissue can be used to foster the development of white blood cells the body needs to mount healthy immune responses and to prevent harmful autoimmune reactions.

17 May 2013

Simvastatin hinders positive effects of exercise for obese adults, say researchers

Statins, the most widely prescribed drugs worldwide, are often suggested to lower cholesterol and prevent heart disease in individuals with obesity, diabetes and metabolic syndrome, which is a combination of medical disorders including excess body fat and/or high levels of blood pressure, blood sugar and/or cholesterol.

17 May 2013

Changes in specific proteins contribute to 'leaky-gut' wall

Scientists at Trinity College Dublin have made an important advance in understanding the biological factors that keep the lining of the gut wall intact. Associate Professor, Maria O'Sullivan at Trinity's School of Medicine and St James's Hospital and colleagues, showed that changes in specific proteins may contribute to a 'leaky-gut' wall which may have important implications for common chronic digestive diseases such as irritable bowel syndrome and inflammatory bowel disease.

17 May 2013

Preclinical study shows PLX cells may help reverse symptoms associated with preeclampsia

Could the answer to repairing the ailing placenta in preeclampsia lie within the stem cells of a healthy placenta? New promising evidence may lead scientists to answer that question.

17 May 2013

People suffering from PTSD have risk of developing type 2 diabetes

The presence of posttraumatic stress disorder is significantly associated with the development of type 2 diabetes. This is the finding of scientists from the Helmholtz Zentrum München and the University Hospital Gieβen and Marburg who worked with data from the population-based KORA cohort study.

16 May 2013

$Study: Long-term mortality in patients with refractory angina is surprisingly low$

Study: Long-term mortality in patients with refractory angina is surprisingly low

Death rates associated with patients with refractory angina, or chronic chest pain, are lower than previously considered; therefore, physicians should focus on relieving the chest pain symptoms and improving the quality of life in these patients according to an article published online this week in the European Heart Journal.

16 May 2013

Tokai Pharmaceuticals raises $35.5M in Series E financing

Tokai Pharmaceuticals, Inc., a biopharmaceutical company focused on developing new treatments for prostate cancer, today announced that the company raised $35.5 million in a Series E financing based on encouraging clinical progress and investor support for galeterone (TOK-001), Tokai's lead prostate cancer drug candidate.

15 May 2013

Exercise is good for us - no matter what our age

The red double-decker buses that are symbolic of the city of London have an altogether different significance if you study heart disease. Sixty years ago, these iconic buses helped a Scottish medical doctor named Jerry Morris discover the link between physical activity and heart attacks.

15 May 2013

Syndrome News and Research

Weekend reading: Mental illness stigma, health insurance mazes and female libido

Wisconsin scientists synthesize potent compounds to curb bacteria that cause staph infections

Early adenotonsillectomy can improve behavior and sleep apnea symptoms in children

Genetic risk factor for pulmonary fibrosis can be used to identify individuals at risk for lung disease

Caltech biologists show that microRNA-146a protects stem cells during inflammation

Study: 3/4 women experience constipation and other bowel disorders during their pregnancies

Researchers develop new mouse model to discover gene pathways that drive MPNST

Research explores pharmaceutical advances for IBS, hepatitis C

Researchers identify novel biomarkers for predicting mortality in ICU patients

New breakthrough in progeria treatment

Neupro reduces PLMS and total NSBP elevations in patients with RLS, study finds

Study examines self-management support in primary care

UCSF researchers create first functioning human thymus tissue from embryonic stem cells

Simvastatin hinders positive effects of exercise for obese adults, say researchers

Changes in specific proteins contribute to 'leaky-gut' wall

Preclinical study shows PLX cells may help reverse symptoms associated with preeclampsia

People suffering from PTSD have risk of developing type 2 diabetes

Study: Long-term mortality in patients with refractory angina is surprisingly low

Tokai Pharmaceuticals raises $35.5M in Series E financing

Exercise is good for us - no matter what our age

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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