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Study to evaluate safety of PrEP and dapivirine ring in pregnant women

A woman who is eight-months pregnant is the first participant to be enrolled into a study evaluating the safety and acceptability of two different HIV prevention approaches when used during pregnancy -- the monthly dapivirine vaginal ring, which is currently under regulatory review, and a daily antiretroviral (ARV) pill called Truvada, an approach already approved in several countries and commonly referred to as PrEP, short for pre-exposure prophylaxis.

10 Feb 2020

New clinical trial to examine the safety of dapivirine vaginal ring and PrEP in pregnant women

The first clinical trial specifically designed to test the safety of the monthly dapivirine vaginal ring in pregnant women has begun in southern and eastern Africa.

10 Feb 2020

Youth with HIV have lower rates of viral suppression than adults

Despite similar rates of enrollment into medical care, youth with HIV have much lower rates of viral suppression--reducing HIV to undetectable levels--compared to adults, according to an analysis funded by the National Institutes of Health.

10 Feb 2020

Higher maternal blood pressure linked to placental gene modifications

Higher maternal blood pressure in pregnancy is associated with chemical modifications to placental genes, according to a study by researchers from the Eunice Kennedy Shriver National Institute of Child Health and Human Development, part of the National Institutes of Health.

10 Feb 2020

George Mason researcher to study link between endometriosis and endocrine disruptors with NIH grant

Dr. Anna Pollack, associate professor at the George Mason College of Health and Human Services has received a $1.6M grant from the National Institute of Environmental Health Sciences to study the link between endometriosis and endocrine-disrupting chemicals.

9 Feb 2020

Study may suggest new therapeutic approaches to control immune responses

Researchers have provided new insight on the role of cyclic AMP (cAMP) in regulating the immune response.

5 Feb 2020

Single-cell DNA assessment method can detect fetal genetic abnormalities

Non-invasive prenatal tests are used for fetal genetic disease screening in pregnant women. In contrast, invasive tests like amniocentesis carry the risk of causing fetal harm.

4 Feb 2020

General anesthesia in cesarean delivery linked with increased risk of postpartum depression

A new study shows that having general anesthesia in a cesarean delivery is linked with significantly increased odds of severe postpartum depression requiring hospitalization, thoughts of suicide or self-inflicted injury.

4 Feb 2020

Study defines safest ovary removal procedure for fertility preservation

Young girls who are about to undergo treatment for cancer or other therapies that pose high risk of infertility can opt to have an ovary removed and preserved for future transplantation when they are ready to pursue pregnancy.

4 Feb 2020

Study finds homicide as leading cause of pregnancy-associated death in Louisiana

Homicide is a leading cause of death among pregnant and postpartum women in Louisiana, according to an analysis of birth and death records from 2016 and 2017.

3 Feb 2020

Mason researchers join NIH grant to investigate early life environmental exposures

Rosemary Higgins, Associate Dean for Research, College of Health and Human Services, and Germaine Buck Louis, Dean, CHHS, received $1,457,607 from the National Institutes of Health for: "ECHO Consortium on Perinatal Programming of Neurodevelopment."

3 Feb 2020

Cooling burns with running water is the best initial treatment, study reveals

New research in the January edition of Annals of Emergency Medicine reveals that cooling with running water is the best initial treatment for a child's burn.

30 Jan 2020

Global study identifies the best city designs to reduce transport-related injuries

City design combining more public transport and rail networks with smaller, low speed blocks are the best to reduce road transport injuries, according to a new global study co-authored by researchers at Columbia University Mailman School of Public Health.

28 Jan 2020

Successful gene therapy trial in patients with X-linked Chronic Septic Granulomatosis

American and British teams led by Drs Kohn (University of California, Los Angeles), Malech (NIH), Williams (Boston Children's) and Trasher (Great Ormond Street Institute of Child Health) published yesterday in Nature Medicine the conclusive results of a gene therapy trial conducted in the United States and Great Britain in 9 patients with X-linked Chronic Septic Granulomatosis (X-CGD), a rare and severe immune dysfunction. Six of them are free of treatment for complications generated by the disease.

28 Jan 2020

NICU babies have higher risk of mental health problems in later life

Children who spend time in a neonatal intensive care unit at birth have a higher risk of mental health issues later, regardless of their birth weight, say McMaster University researchers.

28 Jan 2020

Increased youth suicide rates found in high poverty communities

A study led by Jennifer Hoffmann, MD, from Ann & Robert H. Lurie Children's Hospital of Chicago, found that higher county-level poverty is associated with increased youth suicide rates among children 5-19 years old in the United States in 2007-2016.

27 Jan 2020

Study: Benefits of fetal surgery to repair spina bifida continue through school age

The benefits of fetal surgery to repair spina bifida, a procedure pioneered at Vanderbilt University Medical Center (VUMC) in 1997, continue through school age, a National Institutes of Health (NIH) study reports today in the journal Pediatrics.

24 Jan 2020

Routine Zika vaccination could help prevent suffering and save money

Global climate change has raised concerns that mosquito-borne diseases could become increasingly prevalent in the United States as warmer temperatures lead to increased mosquito activity.

23 Jan 2020

Many youth found to be living with undiagnosed Chronic Fatigue Syndrome

Most youth living with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) have not been diagnosed, according to a new prevalence study from researchers at DePaul University and Ann & Robert H. Lurie Children's Hospital of Chicago, published by the journal Child & Youth Care Forum.

23 Jan 2020

Researcher wins $2.5 million grant to study why therapeutic horseback riding benefits autistic children

After showing that a 10-week therapeutic horseback riding intervention reduced irritability and hyperactivity while improving the social communication skills of youth diagnosed with autism spectrum disorder, University of Colorado Anschutz Medical Campus researcher and Children's Hospital Colorado psychologist, Dr. Robin Gabriels, has received a $2.5 million grant to investigate why the therapy works.

22 Jan 2020

Child Health News and Research

Study to evaluate safety of PrEP and dapivirine ring in pregnant women

New clinical trial to examine the safety of dapivirine vaginal ring and PrEP in pregnant women

Youth with HIV have lower rates of viral suppression than adults

Higher maternal blood pressure linked to placental gene modifications

George Mason researcher to study link between endometriosis and endocrine disruptors with NIH grant

Study may suggest new therapeutic approaches to control immune responses

Single-cell DNA assessment method can detect fetal genetic abnormalities

General anesthesia in cesarean delivery linked with increased risk of postpartum depression

Study defines safest ovary removal procedure for fertility preservation

Study finds homicide as leading cause of pregnancy-associated death in Louisiana

Mason researchers join NIH grant to investigate early life environmental exposures

Cooling burns with running water is the best initial treatment, study reveals

Global study identifies the best city designs to reduce transport-related injuries

Successful gene therapy trial in patients with X-linked Chronic Septic Granulomatosis

NICU babies have higher risk of mental health problems in later life

Increased youth suicide rates found in high poverty communities

Study: Benefits of fetal surgery to repair spina bifida continue through school age

Routine Zika vaccination could help prevent suffering and save money

Many youth found to be living with undiagnosed Chronic Fatigue Syndrome

Researcher wins $2.5 million grant to study why therapeutic horseback riding benefits autistic children

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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