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ArmaGen closes $17M Series A financing

ArmaGen Technologies, Inc. today announced the closing of a $17 million Series A financing to support the development of brain-penetrating recombinant protein therapeutics.

29 Nov 2012

Watch out for Sjögren's syndrome in dry eye

Clinicians with patients who have clinically significant dry eye should be on the alert for underlying Sjögren's syndrome, report researchers in the British Journal of Ophthalmology.

28 Nov 2012

Nontraditional velopharyngoplasty predictor unveiled

The necessity of subsequent velopharyngoplasty does not depend on the time of soft palate closure and type of cleft, say researchers.

28 Nov 2012

Researchers discover alternative mechanism for Ras protein activation

The protein Ras plays an important role in cellular growth control. Researchers have focused on the protein because mutations in its gene are found in more than 30 percent of all cancers, making it the most prevalent human oncogene.

28 Nov 2012

Off label atypical antipsychotic use lacks safety and effectiveness in patients over 40

In older adults, antipsychotic drugs are commonly prescribed off-label for a number of disorders outside of their Food and Drug Administration (FDA)-approved indications - schizophrenia and bipolar disorder. The largest number of antipsychotic prescriptions in older adults is for behavioral disturbances associated with dementia, some of which carry FDA warnings on prescription information for these drugs.

28 Nov 2012

ABCA3 gene associated with respiratory distress syndrome in babies

Some infants are more susceptible to potentially life-threatening breathing problems after birth, and rare, inherited DNA differences may explain why, according to research at Washington University School of Medicine in St. Louis.

28 Nov 2012

Trauma does not negatively impact cognition in schizophrenia

A history of trauma or post-traumatic stress disorder is not associated with poorer cognitive functioning in patients with schizophrenia, researchers report.

27 Nov 2012

Algorithms improve certainty in ruling out deep and pelvic vein thrombosis at primary level of patient care

Algorithms improve certainty in ruling out deep and pelvic vein thrombosis at the primary level of patient care, say Lobna El Tabei and her co-authors in the current issue of the Deutsches Ärzteblatt International.

27 Nov 2012

First Edition: November 27, 2012

Today's headlines include reports about how increasing the Medicare eligibility age and making other entitlement program changes are a part of the ongoing "fiscal cliff" discourse.

27 Nov 2012

Neurofibromatosis-1 may increase risk of breast cancer in women

New Johns Hopkins research showing a more than four-fold increase in the incidence of breast cancer in women with neurofibromatosis-1 (NF1) adds to growing evidence that women with this rare genetic disorder may benefit from early breast cancer screening with mammograms beginning at age 40, and manual breast exams as early as adolescence.

27 Nov 2012

Liver disease therapies: an interview with Eric Halioua, CEO of Promethera Biosciences

Liver disease is a very broad family of diseases. There are two main categories of liver disease:

27 Nov 2012

New SARS-like virus detected in total of six people from Saudi Arabia, Qatar, WHO says

"A new virus from the same family as SARS which sparked a global alert in September has now killed two people in Saudi Arabia, and total cases there and in Qatar have reached six, the World Health Organization said" on Friday, Reuters reports.

27 Nov 2012

Low folate and vitamin B12 intake increase risk of melancholic depressive symptoms

A low intake of folate and vitamin B12 increases the risk of melancholic depressive symptoms, according to a study among nearly 3,000 middle-aged and elderly Finnish subjects. On the other hand, non-melancholic depressive symptoms are associated with an increased risk for the metabolic syndrome.

27 Nov 2012

Azathioprine exposure concerns raised for SLE mothers

Researchers have raised the possibility of an increased risk for developmental delay in the children of mothers who used azathioprine for systemic lupus erythematosus during pregnancy.

26 Nov 2012

Procalcitonin levels help distinguish between pneumonia types

Serum procalcitonin is a useful marker for distinguishing between acute exacerbation of interstitial pneumonia and bacterial pneumonia, say researchers.

26 Nov 2012

Alcohol exposure during fetal development alters brain structure and metabolism in children

Children exposed to alcohol during fetal development exhibit changes in brain structure and metabolism that are visible using various imaging techniques, according to a new study being presented today at the annual meeting of the Radiological Society of North America (RSNA).

26 Nov 2012

Researchers create 3D map of rod sensory cilium architecture affected by mutation

Using a new technique called cryo-electron tomography, two research teams at Baylor College of Medicine (www.bcm.edu) have created a three-dimensional map that gives a better understanding of how the architecture of the rod sensory cilium (part of one type of photoreceptor in the eye) is changed by genetic mutation and how that affects its ability to transport proteins as part of the light-sensing process.

23 Nov 2012

Study to discover exactly how intravenous immune globulin treatments work

Immune globulin replacement began decades ago as a treatment for patients who could not make their own protective antibodies, but has proven to have much broader benefits than originally expected.

22 Nov 2012

Electronic device sniffs out sleep apnea syndrome

An electronic nose could be used to diagnose obstructive sleep apnea syndrome, by detecting the presence of volatile organic molecules in the breath of a patient, research suggests.

22 Nov 2012

Habitual physical activity improves midlife women's health

Moving 6,000 or more steps a day-no matter how-adds up to a healthier life for midlife women. That level of physical activity decreases the risk of diabetes and metabolic syndrome (a diabetes precursor and a risk for cardiovascular disease), showed a study published online this month in Menopause, the journal of the North American Menopause Society.

22 Nov 2012