Syndrome News and Research

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Migraine involves multiple symptoms that vary widely among sufferers

Almost everyone suffers from headache pain occasionally, but for 36 million Americans, intense, debilitating headaches accompanied by other neurological symptoms — also known as migraine syndrome — are a source of physical misery that can have a devastating effect on their quality of life. It is estimated that the medical expenses and loss of productivity caused by migraine costs Americans $20 billion annually.

14 Jul 2012

Psychotic depression now fulfills the criteria for a valid psychiatric syndrome

The number of studies reporting significant and clinically relevant differences between psychotic depression (PD) and non-PD has increased considerably over the past decades. This summary of the current evidence suggests that PD now fulfils the criteria for a valid psychiatric syndrome.

14 Jul 2012

Paper describes novel psychotherapeutic approach in a boy with Asperger's syndrome

This paper reports a stable improvement in social skills in a 15-year-old boy diagnosed with Asperger's syndrome (AS), after an outpatient treatment with Social Effectiveness Therapy for Children and Adolescents (SET-C), a specific and intensive type of social skill training. Its effectiveness should be further tested in randomized controlled and long-term follow-up studies.

14 Jul 2012

Five rare mutations in single gene increase chances of boys developing ASD

Researchers at Emory University School of Medicine have identified five rare mutations in a single gene that appear to increase the chances that a boy will develop an autism spectrum disorder (ASD).

13 Jul 2012

Maraviroc reduces incidence of GvHD in blood cancer patients after bone marrow transplantation

An HIV drug that redirects immune cell traffic significantly reduces the incidence of a dangerous complication that often follows bone marrow transplants for blood cancer patients, according to research from the Perelman School of Medicine at the University of Pennsylvania that will be published today in the New England Journal of Medicine.

12 Jul 2012

SRI receives NIAID grant to develop HIV vaccine

The Scripps Research Institute has been awarded a grant expected to total more than $77 million from the National Institutes of Health's (NIH) National Institute of Allergy and Infectious Diseases (NIAID).

12 Jul 2012

Cochlear implants work well for Waardenburg children

Children with Waardenburg syndrome respond well to cochlear implantation and achieve equally good speech and hearing outcomes as nonsyndromic children undergoing the same procedure, report researchers.

11 Jul 2012

Health risks associated with H1N1 vaccine investigated

Results from two studies published in JAMA show that the H1N1 vaccination is associated with a small, but significant, increase in risk for Guillain-Barré syndrome in adults, but does not increase the risk for birth defects or problems when given to pregnant women.

11 Jul 2012

Visual, auditory hallucinations often co-occur in psychosis patients

Visual hallucinations are common in patients with psychosis spectrum disorders and often co-occur with auditory hallucinations, researchers report.

11 Jul 2012

Exposure to H1N1 vaccine in pregnancy does not increase risk of adverse fetal outcomes

In studies examining the risk of adverse outcomes after receipt of the influenza A(H1N1) vaccine, infants exposed to the vaccine in utero did not have a significantly increased risk of major birth defects, preterm birth, or fetal growth restriction; while in another, study researchers found a small increased risk in adults of the nervous system disorder, Guillain-Barre syndrome, during the 4 to 8 weeks after vaccination, according to 2 studies in the July 11 issue of JAMA.

11 Jul 2012

Study details development of first mouse model for Usher syndrome III

A new study published in the July 11 issue of the Journal of Neuroscience details the development of the first mouse model engineered to carry the most common mutation in Usher syndrome III causative gene (Clarin-1) in North America.

11 Jul 2012

Study investigates effect of SwabCap in catheter maintenance bundle

A disinfection cap used in IV therapy was the subject of an award-winning, multi-site study at a four-hospital, Chicago-area hospital system.

11 Jul 2012

Study assesses risk of GBS following H1N1 vaccine administration

Guillain-Barre syndrome (GBS) is usually characterized by rapidly developing motor weakness and areflexia (the absence of reflexes). "The disease is thought to be autoimmune and triggered by a stimulus of external origin. In 1976-1977, an unusually high rate of GBS was identified in the United States following the administration of inactivated 'swine' influenza A(H1N1) vaccines.

11 Jul 2012

Connections between daily stressors of police work and obesity, suicide

The daily psychological stresses that police officers experience in their work put them at significantly higher risk than the general population for a host of long-term physical and mental health effects. That's the overall finding of a major scientific study of the Buffalo Police Department called Buffalo Cardio-Metabolic Occupational Police Stress (BCOPS) conducted over five years by a University at Buffalo researcher.

11 Jul 2012

Broken heart syndrome arms against epinephrine high

Takotsubo cardiomyopathy, or “broken heart syndrome,” may actually protect the heart from very high levels of epinephrine, suggest results from an animal study.

10 Jul 2012

Liver failure, cancer and mortality in cirrhotic patients coinfected with HIV/AIDS and HCV predicted by liver stiffness

Researchers from Spain established that liver stiffness, measured by transient elastography (TE), is an independent predictor of liver failure, hepatocellular carcinoma (HCC), and mortality in cirrhotic patients coinfected with the human immunodeficiency virus (HIV) or acquired immune deficiency syndrome (AIDS), and hepatitis C virus (HCV).

10 Jul 2012

Surgery advised in face of uncertain sinus sampling result in Cushing patients

Surgeons should consider transsphenoidal surgery in patients with Cushing disease caused by adrenocorticotropic hormone overproduction, almost irrespective of the results of inferior petrosal sinus sampling, say US researchers.

10 Jul 2012

High ferritin warns of bone loss

Individuals with high levels of ferritin, an indicator of iron stores within the body, have accelerated bone loss at the proximal femur, Korean researchers report.

10 Jul 2012

Broken heart syndrome arms against epinephrine high

Takotsubo cardiomyopathy, or “broken heart syndrome,” may actually protect the heart from very high levels of epinephrine, suggest results from an animal study.

10 Jul 2012

MiR-33 plays a key role in regulating bile metabolism

In research funded by the National Institutes of Health and the American Heart Association and published in EMBO Molecular Medicine, Saint Louis University investigator -ngel Bald-n, Ph.D., found that the microRNA miR-33 plays a key role in regulating bile metabolism. Further, the research suggests that, in an animal model, the manipulation of this microRNA can improve the liver toxicity that can be caused by statins.

10 Jul 2012