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Study reveals diverse risk factors for healthy aging in Latin America

A pioneering study published today in the journal Nature Aging has unveiled significant heterogeneity in the risk factors affecting healthy aging in Latin America and emphasized the limitations of current models of brain health, which are primarily based on data from high-income countries.

17 Jun 2024

Over 1 million race records show East Africans as fastest in 50-km ultra-marathons

A study in Scientific Reports analyzed the age and country of elite 50-km ultra-marathon runners, revealing that the fastest athletes are from African countries, with peak performance between ages 20 and 24.

16 Jun 2024

Promising gene editing therapy shows hope in sickle cell disease cure

Researchers have presented the latest findings from a clinical trial aimed at discovering a cure for sickle cell disease, a painful genetic blood disorder with limited treatment options.

14 Jun 2024

New therapeutic approach for Duchenne muscular dystrophy combines LED therapy with idebenone

In an animal model of Duchenne muscular dystrophy, Brazilian researchers tested a therapy that combines photobiomodulation using laser light or light-emitting diodes (LEDs) with idebenone, an antioxidant compound investigated for application in neurodegenerative diseases.

14 Jun 2024

The hidden genetic switches influencing human height and bone health

In mammals, only 3% of the genome consists of coding genes which, when transcribed into proteins, ensure the biological functions of the organism and the in-utero development of future individuals. But genes do not function alone.

14 Jun 2024

Study reveals why EGFR inhibitors fail in some non-smokers with lung cancer

The reason why targeted treatment for non-small cell lung cancer fails to work for some patients, particularly those who have never smoked, has been discovered by researchers from UCL, the Francis Crick Institute and AstraZeneca.

13 Jun 2024

Study sheds light on pediatric DIPG tumor mechanisms

Researchers at the University of Michigan Health Rogel Cancer Center are one step closer to understanding how pediatric DIPG tumors work.

13 Jun 2024

Japanese study sheds light on genetic counseling for AATRv amyloidosis

Early detection and treatment of hereditary transthyretin-related amyloidosis via genetic counseling are crucial.

13 Jun 2024

Study uncovers why targeted therapy fails in some non-small cell lung cancer patients

13 Jun 2024

Open-ILD: Pioneering stem cell research to combat interstitial lung disease

Imagine a world where breathing is a luxury and a cough marks the sound of an inner battle. Interstitial Lung Disease (ILD), a condition characterised by inflammation and fibrosis, is a major cause of severe respiratory illness and can occur in children.

13 Jun 2024

Stanford study finds low risk of secondary blood cancers after CAR-T cell therapy

A large study by researchers at Stanford Medicine has found that the risk of secondary blood cancers after CAR-T cell therapy -; a cell-based cancer treatment that exploded on the scene in 2017 as a treatment for intractable blood cancers -; is low, despite a Food and Drug Administration warning.

12 Jun 2024

Integration of genomics, epigenomics, and transcriptomics in understanding Alzheimer's pathogenesis

With the advent of new omics technologies in recent years, there has been a deluge of complex, high-dimensional data on Alzheimer's disease (AD).

12 Jun 2024

New AARF-D award supports Temple researchers to explore synapse function in the aging brain

Late-life depression is a major risk factor for Alzheimer's disease, in particular because it accelerates progression from mild cognitive impairment to dementia.

12 Jun 2024

Long-read RNA sequencing reveals novel insights into alternative splicing and disease genetics

Tokyo Medical and Dental University (TMDU) researchers harness long-read RNA sequencing to decode genetic intricacies and disease links.

12 Jun 2024

HiDEF-seq technique reveals the origins of DNA mutations in single strands

Mutations are changes in the molecular "letters" that make up the DNA code, the blueprint for all living cells. Some of these changes can have little effect, but others can lead to diseases, including cancer.

12 Jun 2024

Study identifies genetic predictors of X chromosome loss in aging women

Researchers have identified inherited genetic variants that may predict the loss of one copy of a woman's two X chromosomes as she ages, a phenomenon known as mosaic loss of chromosome X, or mLOX.

12 Jun 2024

Enhancing CAR-T cell therapy with biodegradable scaffolds

CAR-T cell therapies are transforming the treatment of previously incurable blood cancers. Six approved CAR-T products have been administered to more than 20,000 people, and more than 500 clinical trials are underway.

12 Jun 2024

H5N1 influenza outbreak in Texas dairy cattle sparks multi-species transmission concerns

Study identifies H5N1 influenza as the cause of an outbreak among dairy cattle in Texas, highlighting the risk of multi-species viral transmission and potential implications for human health.

11 Jun 2024

Exposure to phthalates during pregnancy linked to increased risk of hypertension and preeclampsia

Study links phthalate exposure during pregnancy to a higher risk of hypertensive disorders, including preeclampsia. Findings highlight the need for preventive strategies to reduce this risk.

11 Jun 2024

Mount Sinai researchers use AI to identify 17 key genes in heart disease

Using an advanced artificial intelligence tool, researchers at the Icahn School of Medicine at Mount Sinai have identified rare coding variants in 17 genes that shed light on the molecular basis of coronary artery disease (CAD), the leading cause of morbidity and mortality worldwide.

11 Jun 2024

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Genetic News and Research

Study reveals diverse risk factors for healthy aging in Latin America

Over 1 million race records show East Africans as fastest in 50-km ultra-marathons

Promising gene editing therapy shows hope in sickle cell disease cure

New therapeutic approach for Duchenne muscular dystrophy combines LED therapy with idebenone

The hidden genetic switches influencing human height and bone health

Study reveals why EGFR inhibitors fail in some non-smokers with lung cancer

Study sheds light on pediatric DIPG tumor mechanisms

Japanese study sheds light on genetic counseling for AATRv amyloidosis

Study uncovers why targeted therapy fails in some non-small cell lung cancer patients

Open-ILD: Pioneering stem cell research to combat interstitial lung disease

Stanford study finds low risk of secondary blood cancers after CAR-T cell therapy

Integration of genomics, epigenomics, and transcriptomics in understanding Alzheimer's pathogenesis

New AARF-D award supports Temple researchers to explore synapse function in the aging brain

Long-read RNA sequencing reveals novel insights into alternative splicing and disease genetics

HiDEF-seq technique reveals the origins of DNA mutations in single strands

Study identifies genetic predictors of X chromosome loss in aging women

Enhancing CAR-T cell therapy with biodegradable scaffolds

H5N1 influenza outbreak in Texas dairy cattle sparks multi-species transmission concerns

Exposure to phthalates during pregnancy linked to increased risk of hypertension and preeclampsia

Mount Sinai researchers use AI to identify 17 key genes in heart disease

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