ACE2 News and Research

RSS

Uptake of SARS-CoV-2 spike protein in human cerebrovascular cells

A recent study assessed the uptake of SARS-CoV-2 spike protein in human cerebrovascular cells via the lipid raft ganglioside.

24 Mar 2022

Researchers investigate Galectin-9 as a new treatment target for COVID-19

Researchers discuss alternate therapeutic targets for treating COVID-19 and the effects of Gal-9 on SARS-CoV-2 infection and the immune response.

23 Mar 2022

Study discovers potent and selective human monoclonal antibodies against Omicron variant of SARS-CoV-2

In a new study, researchers discovered human monoclonal antibodies, which were specific and potent against the severe acute respiratory syndrome coronavirus 2 Omicron variant.

23 Mar 2022

Umbrella analysis of the effect of renin-angiotensin-aldosterone system inhibitors on COVID-19 related outcomes

Researchers conducted an umbrella review and meta-analysis of the RAAS inhibitors' impact on COVID-19 clinical outcomes.

23 Mar 2022

Novel monoclonal antibody found to have substantial neutralizing capacity against SARS-CoV-2 Omicron variant

Researchers reported a new monoclonal antibody, P2G3, which significantly neutralized the SARS-CoV-2 Omicron variant.

23 Mar 2022

Importance of Numb-associated kinases in SARS-CoV-2 infection

A new study posted to the bioRxiv* preprint server has focussed on assessing four members of the NAK family that are associated with SARS-CoV-2 infection. These kininases could act as a target for the development of effective COVID-19 therapeutics.

23 Mar 2022

Study reveals differences in SARS-CoV-2 and SARS-CoV-1 spike protein conformational changes

Researchers determine the differential dynamic behavior of SARS-CoV-1 and SARS-CoV-2 spike proteins.

22 Mar 2022

CD63-expressing extracellular vesicles neutralize SARS-CoV-2 variants of concern

Researchers evaluate antiviral effects of CD63 tetraspanin extracellular vesicles against SARS-CoV-2 and HIV-1.

22 Mar 2022

Molecular dynamic simulations unveil conformational dynamics of SARS-CoV-2 spike protein RBD and ACE2 receptor

Researchers presented a systematic analysis of the affinity and conformational dynamics between the binding of SARS-CoV-2 receptor-binding domain spike protein and the host angiotensin-converting enzyme 2 receptor.

22 Mar 2022

Study evaluates interactions between SARS-CoV-2 proteins and viral and host RNA

A new study investigated the interactions between SARS-CoV-2 proteins and viral and host ribonucleic acid in virus-infected cells.

22 Mar 2022

Angiotensin-converting enzyme 2 allosteric binders found to be effective against SARS-CoV-2

Researchers reported a hybrid approach comprising computational models and high throughput screening to discover allosteric ACE2 binders inhibiting viral replication without interrupting ACE2 renal, pulmonary, immune, and cardiovascular functions.

22 Mar 2022

Is COVID-19 on the verge of ending?

Researchers explore the changes arising in SARS-CoV-2 over time.

21 Mar 2022

Study aimed to identify the direct pathway that associates integrins with vascular dysregulation during SARS-CoV-2 infection

Researchers demonstrated the role of integrin signaling in vascular dysfunction associated with SARS-CoV-2 infection.

21 Mar 2022

The importance of the endosomal pathway for SARS-CoV-2 entry

Researchers demonstrated that combined inhibition of cell-surface-based and endosomal pathways completely blocked SARS-CoV-2 entry into mammalian cells.

21 Mar 2022

Study unveils several natural marine products as potential agents against SARS-CoV-2

A recent study, published in the Journal of Natural Products of the American Chemical Society and American Society of Pharmacognosy, highlighted three natural marine products as potent inhibitors of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – without any apparent toxic effects for human lung cells.

21 Mar 2022

ACE2 News and Research

Uptake of SARS-CoV-2 spike protein in human cerebrovascular cells

Researchers investigate Galectin-9 as a new treatment target for COVID-19

Study discovers potent and selective human monoclonal antibodies against Omicron variant of SARS-CoV-2

Umbrella analysis of the effect of renin-angiotensin-aldosterone system inhibitors on COVID-19 related outcomes

Novel monoclonal antibody found to have substantial neutralizing capacity against SARS-CoV-2 Omicron variant

Importance of Numb-associated kinases in SARS-CoV-2 infection

Study reveals differences in SARS-CoV-2 and SARS-CoV-1 spike protein conformational changes

CD63-expressing extracellular vesicles neutralize SARS-CoV-2 variants of concern

Molecular dynamic simulations unveil conformational dynamics of SARS-CoV-2 spike protein RBD and ACE2 receptor

Study evaluates interactions between SARS-CoV-2 proteins and viral and host RNA

Angiotensin-converting enzyme 2 allosteric binders found to be effective against SARS-CoV-2

Is COVID-19 on the verge of ending?

Study aimed to identify the direct pathway that associates integrins with vascular dysregulation during SARS-CoV-2 infection

The importance of the endosomal pathway for SARS-CoV-2 entry

Study unveils several natural marine products as potential agents against SARS-CoV-2

Covalent protein nanobodies for neutralizing SARS-CoV-2 and its variants

Hypoxia-inducible factors and SARS-CoV-2 manifestations

Study explores SARS-CoV-2 spike epitope with potent and broad neutralization

Why does the SARS-CoV-2 Omicron variant escape immunity?

Study reports thiopurines inhibit the replication of the betacoronaviruses HCoV-OC43 and SARS-CoV-2

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest News