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White blood cell count as a prognostic indicator of COVID-19

Based on a new study, researchers concluded WBC count variations worsen clinical outcomes such as severity, mortality, and hospital discharge rates leading to a poorer prognosis in COVID-19 patients.

23 Feb 2022

Study demonstrates that TMPRSS2, which is key to SARS-CoV-2 cell entry, is a tumor suppressor

The role played by the host enzyme TMPRSS2 in infection and cancer is the focus of a new study.

23 Feb 2022

Study proposes SARS-CoV-2-encoded peptide presented by HLA-E may suppress inhibition of natural killer cells

A recent study reported the abrogation of inhibition of the NK cells by a SARS-CoV-2-encoded protein presented by HLA-E.

23 Feb 2022

Study explores the impact of COVID-19 on pancreatic cells

New study findings showed that SARS-CoV-2 caused a productive yet restricted infection of pancreatic islet cells and an insignificant inflammatory response.

23 Feb 2022

hAELVi cell infection model mimics SARS-CoV-2 Omicron infection in lower respiratory tract of humans

In a recent study posted to the Research Square* preprint server, which is under consideration at Scientific Reports, a team of researchers developed a novel human Alveolar Epithelial Lentivirus immortalized (hAELVi) cell infection model to estimate the replication potential of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other respiratory viruses in the lower respiratory tract of humans.

23 Feb 2022

SARS-CoV-2 Omicron variant rapidly takes over Delta viral strain in Norwegian households

Researchers compared the secondary attack rates SARS-CoV-2 Omicron and Delta variants of concern in Norwegian households.

22 Feb 2022

Research explains how SARS-CoV-2 variants evade some antibodies

A recent study published in the iScience Journal assessed the influence of new variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on coronavirus disease 2019 (COVID-19) infectivity and viral neutralization.

22 Feb 2022

Global SARS-CoV-2 genetic sequence distribution in early COVID-19

In a recent study published in the journal PLoS ONE, researchers evaluated the temporal spread and geographic distribution of severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) genomic variants.

21 Feb 2022

Broad-spectrum antiviral activity of picolinic acid against SARS-CoV-2 and Influenza A virus

Researchers investigate the potential of picolinic acid (PA) as an anti-SARS-CoV-2 treatment option.

21 Feb 2022

Novel ACE2-blocking antibody protects against all SARS-CoV-2 VOCs

Researchers identify 87G7, a SARS-CoV-2 neutralizing human monoclonal antibody with remarkable broad-spectrum neutralization and protection efficacy.

21 Feb 2022

SARS-CoV-2 Omicron variant prompts system sciences and precision medicine

In a new review study, researchers aimed to describe the emergence of the Omicron variant, its structure, its impact on health and health systems, and the challenges that can be expected due to this variant.

21 Feb 2022

Molecular characteristics of SARS-CoV-2 variants enabling antibody escape

A new review paper published in PLoS Pathogens discusses the new variants and the structural mechanism underlying antibody-mediated neutralization as well as mutational antibody escape.

21 Feb 2022

Surfactant-containing oral mouthwashes target the lipid envelope of SARS-CoV-2

Researchers demonstrated the composition and importance of SARS-CoV-2 lipid envelope and assessed the antiviral potential of oral mouthwashes targeting these lipid envelopes.

21 Feb 2022

Comparing the genomic landscapes of SARS-CoV-2 isolated from animal species relative to that in humans

A recent study identified six candidate mutations in the SARS-CoV-2 genome adaptive to animal hosts.

21 Feb 2022

N-glycosylation blockers reduce SARS-CoV-2 infection

A new Virology study shows that the N-glycosylation pattern of SARS-CoV-2 is crucial to normal spike activity.

20 Feb 2022

Mechanism of fatty-acid coupled adaptive immunity in SARS-CoV-2 revealed

A new study explains how SARS-CoV-2 adapts its immunogenicity to the immune response of the host.

20 Feb 2022

Researchers develop novel anti-SARS-CoV-2 Omicron vaccine candidate

Researchers have developed a new vaccine candidate that is specifically targeted against the SARS-CoV-2 Omicron variant.

20 Feb 2022

The impact of SARS-CoV-2 on lipids

SARS-CoV-2 appears to alter host lipid biosynthesis by relying on certain human metabolic pathways to survive and multiply effectively.

20 Feb 2022

Study reports a highly attenuated SARS-CoV-2 that could serve as a live-attenuated vaccine platform

The research showed a highly attenuated SARS-CoV-2 strain that might be used as a live-attenuated vaccine platform and a BSL-2 experimental system.

18 Feb 2022

Response of peripheral immune cells to ex vivo SARS-CoV-2 exposure compared to SARS-CoV

Researchers characterized the responses of the PBMCs at the individual cell and cell type levels against SARS-CoV-2 and SARS-CoV ex vivo.

18 Feb 2022

ACE2 News and Research

White blood cell count as a prognostic indicator of COVID-19

Study demonstrates that TMPRSS2, which is key to SARS-CoV-2 cell entry, is a tumor suppressor

Study proposes SARS-CoV-2-encoded peptide presented by HLA-E may suppress inhibition of natural killer cells

Study explores the impact of COVID-19 on pancreatic cells

hAELVi cell infection model mimics SARS-CoV-2 Omicron infection in lower respiratory tract of humans

SARS-CoV-2 Omicron variant rapidly takes over Delta viral strain in Norwegian households

Research explains how SARS-CoV-2 variants evade some antibodies

Global SARS-CoV-2 genetic sequence distribution in early COVID-19

Broad-spectrum antiviral activity of picolinic acid against SARS-CoV-2 and Influenza A virus

Novel ACE2-blocking antibody protects against all SARS-CoV-2 VOCs

SARS-CoV-2 Omicron variant prompts system sciences and precision medicine

Molecular characteristics of SARS-CoV-2 variants enabling antibody escape

Surfactant-containing oral mouthwashes target the lipid envelope of SARS-CoV-2

Comparing the genomic landscapes of SARS-CoV-2 isolated from animal species relative to that in humans

N-glycosylation blockers reduce SARS-CoV-2 infection

Mechanism of fatty-acid coupled adaptive immunity in SARS-CoV-2 revealed

Researchers develop novel anti-SARS-CoV-2 Omicron vaccine candidate

The impact of SARS-CoV-2 on lipids

Study reports a highly attenuated SARS-CoV-2 that could serve as a live-attenuated vaccine platform

Response of peripheral immune cells to ex vivo SARS-CoV-2 exposure compared to SARS-CoV

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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