Acetylation News and Research

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Acetylation (or in IUPAC nomenclature ethanoylation) describes a reaction that introduces an acetyl functional group into an organic compound. Deacetylation is the removal of the acetyl group.

Innovations in baculovirus–insect cell expression systems

The baculovirus–insect cell expression system—insect cells used in conjunction with the baculovirus expression vector system (BEVS)— remains a crucial technology for manufacturing large and complex proteins. This eukaryotic expression system offers inherent safety, ease of scale-up, flexible product design, and versatility for a broad range of proteins.

From Sino Biological Inc. 20 Sep 2023

Can yoga alleviate rheumatoid arthritis severity?

A recent Scientific Reports study investigated the effect of yoga on rheumatoid arthritis (RA) severity.

13 Sep 2023

Unlocking the secret drivers of deadly pancreatic cancer: New target offers hope for treatment

Researchers identify a super-enhancer-regulated RNA-binding protein cascade that drives the growth of pancreatic ductal adenocarcinoma, a deadly form of pancreatic cancer. The discovery offers a promising new avenue for targeted therapy, potentially sidestepping severe side effects associated with other treatments.

10 Sep 2023

Gene variant protects against Alzheimer's and Parkinson's diseases

About one in every five people carries a version of a gene that, although largely unsung, appears to confer protection against both Alzheimer's disease and Parkinson's disease, Stanford Medicine investigators and their colleagues have learned.

30 Aug 2023

Research shows how mosquito-transmitted viruses hijack host cells to promote infection

New Cleveland Clinic research shows how mosquito-transmitted viruses – like Zika, West Nile, Yellow Fever and dengue viruses – hijack host cells to promote their own replication and infection.

16 Aug 2023

The interplay between immunity, the nervous system, and microbiota

Researchers review the influence of the gut microbiota on neural and immune network

15 Aug 2023

Scientists identify key proteins driving cancer across multiple tumor types

Scientists have completed a deep analysis of the proteins driving cancer across multiple tumor types, information that can't be assessed by genome sequencing alone.

14 Aug 2023

The impact of epigenetic features on breast cancer treatment and outcomes

The impact of epigenetic features on breast cancer treatment and outcomes.

9 Aug 2023

Recent advances in the understanding of the role and mechanism of CCAR2 in cancer

Researchers described the dual role of cell cycle and apoptosis regulator 2 (CCAR2) in cancer progression as a tumor suppressor and promoter.

4 Aug 2023

Study shows that anti-PTM antibodies are often present in autoimmune mediated liver disease

A recent study published in Frontiers in Medicine described anti-post-translational modification (PTM) antibodies in patients with autoimmune-mediated and cholestatic liver diseases (AILD).

31 Jul 2023

Study illuminates new connections between diet and immunity

A metabolic by-product that is more prevalent during fasting may supercharge immune cells as they fight infection and disease, reports an early stage study by Van Andel Institute scientists and collaborators.

28 Jul 2023

New targets for psoriasis treatment? Study reveals 165 associated genes

Researchers conducted a transcriptome-wide association study.

25 Jul 2023

New assay identifies patients with altered p300/CBP acetylation in castration-resistant prostate cancer

A new research paper was published in Oncotarget's Volume 14 on July 20, 2023, entitled, "Development of a multiplex assay to assess activated p300/CBP in circulating prostate tumor cells."

24 Jul 2023

The role of airway epithelium: insights into asthma and COPD pathogenesis

Study discussed how injury and abnormal repair of the airway epithelium drive chronic obstructive pulmonary disease (COPD) and asthma.

17 Jul 2023

Study shows therapeutic potential of HK for treating degenerative rotator cuff injury in humans

The incidence of degenerative rotator cuff injury in the elderly poses a significant economic burden. A novel study by investigators in The American Journal of Pathology, published by Elsevier, has established that mitochondrial sirtuin 3 (SIRT3) activator honokiol (HK) promotes healing of rotator cuff injury in aged mice.

20 Jun 2023

Acetylation News and Research

Further Reading

Innovations in baculovirus–insect cell expression systems

Can yoga alleviate rheumatoid arthritis severity?

Unlocking the secret drivers of deadly pancreatic cancer: New target offers hope for treatment

Gene variant protects against Alzheimer's and Parkinson's diseases

Research shows how mosquito-transmitted viruses hijack host cells to promote infection

The interplay between immunity, the nervous system, and microbiota

Scientists identify key proteins driving cancer across multiple tumor types

The impact of epigenetic features on breast cancer treatment and outcomes

Recent advances in the understanding of the role and mechanism of CCAR2 in cancer

Study shows that anti-PTM antibodies are often present in autoimmune mediated liver disease

Study illuminates new connections between diet and immunity

New targets for psoriasis treatment? Study reveals 165 associated genes

New assay identifies patients with altered p300/CBP acetylation in castration-resistant prostate cancer

The role of airway epithelium: insights into asthma and COPD pathogenesis

Study shows therapeutic potential of HK for treating degenerative rotator cuff injury in humans

Targeting uncontrolled inflammation may make tumors more responsive to treatment

COVID-19 activates endogenous retroviruses within our genome

Investigating how gut microbiota affect neuroplasticity and neurodevelopment

Protein adduction and p53 tumor suppressor inhibition

Scientists demonstrate how microbiome and feeding patterns impact circadian rhythms in the gut

Innovations in baculovirus–insect cell expression systems

Compound Management and its Crucial Role in Early Pharmaceutical Research

Natural products: the next frontier in drug discovery

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