Acute Kidney Injury News and Research

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Acute kidney injury (AKI) involves sudden damage to the kidneys or decrease in renal function that occurs over a few hours or days. The severity of the condition can vary from a minor loss of kidney function to kidney failure.

Study finds main reasons why people die after noncardiac surgery

The main reasons why people die after noncardiac surgery are revealed today in a study of more than 40,000 patients from six continents presented in a late breaking science session at ESC Congress 2018.

27 Aug 2018

Federal grant extends and expands research into acute kidney failure

The National Institute of Diabetes and Digestive and Kidney Diseases has renewed a grant shared by the University of Alabama at Birmingham School of Medicine and the University of California at San Diego School of Medicine that will extend and expand research into acute kidney failure, or acute kidney injury, which affects about 1.2 million hospitalized patients per year and kills 70 to 80 percent of patients in intensive care units who develop the disease.

22 Aug 2018

Researchers receive multi-million-dollar grant to expand kidney research

Researchers at University of California San Diego School of Medicine and the University of Alabama at Birmingham School of Medicine have received renewed grant funding from the National Institute of Diabetes and Digestive and Kidney Diseases to expand research into the areas of acute kidney failure and acute kidney injuries.

21 Aug 2018

A form of vitamin B3 shows potential to prevent acute kidney injury

Acute kidney injury, an often fatal condition without a specific treatment, affects up to 10 percent of all hospitalized adults in the United States and 30-40 percent in low-income countries.

21 Aug 2018

CNDA approves KEYTRUDA for treatment of advanced melanoma

Merck, known as MSD outside the United States and Canada, today announced that KEYTRUDA, Merck's anti-PD-1 therapy, has been approved by the China National Drug Administration for the treatment of adult patients with unresectable or metastatic melanoma following failure of one prior line of therapy.

26 Jul 2018

Aggressive lowering of blood pressure reduces MCI risk, study shows

Significant reductions in the risk of mild cognitive impairment (MCI), and the combination of MCI and dementia, have been shown for the first time through aggressive lowering of systolic blood pressure in new research results from the federally-funded SPRINT MIND Study reported at the Alzheimer's Association International Conference 2018 in Chicago.

25 Jul 2018

Phase 3 study of KEYTRUDA monotherapy meets primary endpoint

Merck, known as MSD outside the United States and Canada, announced today that the pivotal Phase 3 KEYNOTE-048 trial investigating KEYTRUDA, Merck's anti-PD-1 therapy, for first-line treatment of recurrent or metastatic head and neck squamous cell carcinoma, met a primary endpoint of overall survival as monotherapy in patients whose tumors expressed PD-L1.

25 Jul 2018

Study finds discharge against medical advice as predictor of readmissions in heart attack patients

In a new study led by Keele University researchers found discharge against medical advice as the strongest predictor of 30-day unplanned readmissions in heart attack patients.

18 Jul 2018

St Helens uses Patientrack e-observations system to enhance fluid balance monitoring, reduce mortality risks

NHS professionals at a North West trust have been shortlisted for the prestigious national Patient Safety Awards, following important work around rapid response for deteriorating patients.

3 Jul 2018

Merck announces FDA acceptance of supplemental Biologics License Application for KEYTRUDA

Merck, known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration has accepted for standard review a new supplemental Biologics License Application for KEYTRUDA, Merck's anti-PD-1 therapy, as adjuvant therapy in the treatment of patients with resected, high-risk stage III melanoma and granted a Prescription Drug User Fee Act, or target action, date of February 16, 2019.

25 Jun 2018

Administering nitric oxide gas after heart surgery may decrease risk of kidney problems

Administration of nitric oxide gas during and for 24 hours following heart surgery decreased the risk of patients developing acute and chronic kidney problems, a randomized, controlled trial conducted in China found.

22 Jun 2018

Scientists develop algorithm to predict hypotension during surgery

Scientists have developed an algorithm that predicts potentially dangerous low blood pressure, or hypotension, that can occur during surgery.

11 Jun 2018

Opdivo plus low-dose Yervoy shows promising results in treating renal cell carcinoma patients

Bristol-Myers Squibb Company today announced patient-reported outcomes data from the Phase 3 CheckMate -214 trial in intermediate- and poor-risk patients with advanced renal cell carcinoma treated with the Immuno-Oncology combination Opdivo plus low-dose Yervoy versus sunitinib over a two-year follow-up period.

1 Jun 2018

Study: Acute kidney injury linked with higher risk of cardiovascular events post hospital discharge

Acute kidney injury (AKI), an abrupt or rapid decline in kidney function, is an increasingly prevalent and potentially serious condition that often arises due to medical conditions or treatments that may deprive the kidneys of a normal blood flow or damage kidney tissue.

18 May 2018

Acetaminophen use helps reduce acute kidney injury risk in pediatric heart surgery patients

Children who underwent cardiac surgery were less likely to develop acute kidney injury if they had been treated with acetaminophen in the first 48 hours after their procedures, according to a Vanderbilt study just published in JAMA Pediatrics.

15 May 2018

UH professor receives NIH grant to protect kidneys from obesity

UH professor of pharmacology Tahir Hussain has received $1.6M from the National Institutes of Health to examine a kidney cell that could prevent damage from inflammation caused by obesity.

7 May 2018

Study shows effectiveness of novel risk tool to predict readmission rates after TAVR

A new study looked at the effectiveness of novel risk tool to predict 30-day readmission rates in patients undergoing transcatheter aortic valve replacement.

27 Apr 2018

Clinical trial to examine stem cell therapy for treatment, prevention of complications after traumatic injury

The University of Texas Health Science Center at Houston has received funding through a public/private partnership for the first-ever clinical trial investigating a stem cell therapy for early treatment and prevention of complications after severe traumatic injury.

23 Apr 2018

Researchers explore treatment target for acute kidney injury

When you have diabetes then get an acute kidney injury there is a multiplier effect that can worsen your prognosis and destroy your kidneys.

10 Apr 2018

Caffeine may help neonates at increased risk of acute kidney injury

Preterm neonates who are exposed to caffeine within the first seven days after birth have reduced incidence and severity of acute kidney injuries than neonates who did not, according to findings from the Neonatal Kidney Collaborative's Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates study, published in JAMA Pediatrics.

3 Apr 2018