Adalimumab News and Research

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Adalimumab is an injectable prescription drug used to treat diseases of the immune system; it is marketed by Abbot as Humira. It is one of three drugs that work by inhibiting the potent inflammatory molecule tumor necrosis factor-alpha (TNF-alpha); the others are etanercept (Enbrel) and infliximab (Remicade). Like etanercept and infliximab, adalimumab is a large protein molecule made with recombinant DNA technology. Adalimumab is a monoclonal antibody of the IgG1 subtype that has been "humanized", meaning that all of its components are derived from human molecules.
Study: Early advanced therapy significantly improves Crohn's disease outcomes

Study: Early advanced therapy significantly improves Crohn's disease outcomes

A new test could save arthritis patients time, money, and pain. But will it be used?

A new test could save arthritis patients time, money, and pain. But will it be used?

Charting the future of IBD treatment: From immune modulators to microRNA therapies

Charting the future of IBD treatment: From immune modulators to microRNA therapies

Using TNF inhibitors during pregnancy not associated with worse fetal or obstetric outcomes

Using TNF inhibitors during pregnancy not associated with worse fetal or obstetric outcomes

Novel and emerging therapies offer new hope for patients with inflammatory bowel disease

Novel and emerging therapies offer new hope for patients with inflammatory bowel disease

Lack of direct comparisons prevents assessment of upadacitinib's benefit in Crohn's disease

Lack of direct comparisons prevents assessment of upadacitinib's benefit in Crohn's disease

Effectiveness of Lactobacillus in treating inflammatory bowel disease

Effectiveness of Lactobacillus in treating inflammatory bowel disease

How have inflammatory bowel disease treatments changed after the introduction of biologics?

How have inflammatory bowel disease treatments changed after the introduction of biologics?

Are antidrug antibodies reducing the effectiveness of rheumatoid arthritis treatment?

Are antidrug antibodies reducing the effectiveness of rheumatoid arthritis treatment?

"Smart" sutures can detect inflammation and release drugs

"Smart" sutures can detect inflammation and release drugs

Clinical trial findings may be a game changer in the treatment of pediatric Crohn's disease

Clinical trial findings may be a game changer in the treatment of pediatric Crohn's disease

Study suggests mRNA vaccines decouple SARS-CoV-2 immunity from autoantibody responses observed during acute COVID-19

Study suggests mRNA vaccines decouple SARS-CoV-2 immunity from autoantibody responses observed during acute COVID-19

Study shows how arthritis affects people's working lives

Study shows how arthritis affects people's working lives

New treatment guidelines published for anorectal abscess, anal fistula, and rectovaginal fistula

New treatment guidelines published for anorectal abscess, anal fistula, and rectovaginal fistula

Risk of severe COVID-19 in adults with immune-mediated inflammatory diseases and those on immune-modifying therapies

Risk of severe COVID-19 in adults with immune-mediated inflammatory diseases and those on immune-modifying therapies

People with inflammatory immune conditions had increased risk of COVID-19-related death before vaccination

People with inflammatory immune conditions had increased risk of COVID-19-related death before vaccination

Trial shows the efficacy of anti-TNF drug for patients with early-stage Dupuytren's disease

Trial shows the efficacy of anti-TNF drug for patients with early-stage Dupuytren's disease

Research provides a roadmap for new therapies to treat chorioamnionitis

Research provides a roadmap for new therapies to treat chorioamnionitis

Intensive treatment for patients with Crohn's disease found to be safe

Intensive treatment for patients with Crohn's disease found to be safe

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