Adenocarcinoma News and Research

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Adenocarcinoma is cancer that begins in cells that line certain internal organs and that have gland-like (secretory) properties.

Study reveals key signaling pathways driving lung cancer metastasis

When it comes to cancer metastasis, it takes two to tango. That was one of the key findings of a new study led by researchers at Memorial Sloan Kettering Cancer Center (MSK): The TGF-beta and RAS signaling pathways work together to spur the spread of cancer in lung adenocarcinoma, a leading cause of cancer deaths around the world.

6 Sep 2024

New evidence supports continuous infusion for GI cancers

New research just published online by JNCCN-; Journal of the National Comprehensive Cancer Network finds that for many commonly used treatment regimens targeting metastatic gastrointestinal (GI) cancers, such as FOLFOX, FOLFIRI, or FOLFIRINOX, it is possible to administer 5-FU solely through continuous infusion, minus the bolus (quick-delivery via intravenous push) component, without negatively affecting patient outcomes.

6 Sep 2024

Study finds early pancreatic cancer staging often inaccurate

Staging of patients with early pancreatic cancer is inaccurate as much as 80% of the time, according to a new Cedars-Sinai Cancer study published in the peer-reviewed journal JAMA.

5 Sep 2024

A novel therapeutic option for HER2-positive extramammary Paget disease

The research article presents a comprehensive evaluation of the human epidermal growth factor receptor 2 (HER2) status in extramammary Paget disease (EMPD) and explores the therapeutic potential of disitamab vedotin (DV), a novel humanized anti-HER2 antibody-drug conjugate (ADC), for this rare adenocarcinoma.

4 Sep 2024

Researchers demonstrate a new method to combat pancreatic cancer

Researchers at the University of Massachusetts Amherst and UMass Chan Medical School have demonstrated in mice a new method to combat pancreatic cancer.

28 Aug 2024

Common chemotherapy supplement weakens the pancreatic cancer's defenses in mice

The fight against cancer is an arms race, and one of the most effective weapons in clinicians' arsenals is immunotherapy. Immune checkpoint therapy has become the standard for treating several types of cancer.

27 Aug 2024

Total neoadjuvant therapy shows promising results in routine care for advanced rectal cancer

Research on a modified TNT regimen for high-risk rectal cancer reveals similar complete response rates and lower toxicity compared to traditional approaches.

26 Aug 2024

New AI-driven platform enhances lung cancer tissue analysis

A team of researchers from the University of Cologne's Faculty of Medicine and University Hospital Cologne, led by Dr Yuri Tolkach and Professor Dr Reinhard Büttner, has created a digital pathology platform based on artificial intelligence.

23 Aug 2024

Experts release revised lung cancer testing guidelines

The College of American Pathologists (CAP), the International Association for the Study of Lung Cancer (IASLC), and the Association for Molecular Pathology (AMP) announced today the open comment period for the revised 2018 evidence-based guideline, "Updated Molecular Testing Guideline for the Selection of Lung Cancer Patients for Treatment With Targeted Tyrosine Kinase Inhibitors."

23 Aug 2024

Research identifies 31 additional cancers potentially linked to obesity

This research identifies 18 potential obesity-related cancers, revealing significant associations with BMI and underscoring obesity's impact on cancer risk.

22 Aug 2024

Progress and future directions in esophageal cancer screening in China

Esophageal cancer, a highly aggressive malignancy originating in the esophageal epithelium, poses significant public health challenges in China, where it ranks sixth in incidence and fifth in mortality among cancers.

20 Aug 2024

Advances in precision medicine enhance cancer immunotherapy

The field of precision medicine, especially in the context of cancer immunotherapy, has seen significant advancements in recent years.

20 Aug 2024

The real cost of processed foods: How Western diets are harming global health

A recent study in Nature Medicine reviews the adverse effects of Western diets on human health, highlighting increased risks of chronic diseases and gut dysbiosis. Researchers call for global awareness and promotion of healthier dietary patterns.

6 Aug 2024

Innovative dual-drug strategy for colorectal cancer treatment

A combination of two drugs was capable of suppressing tumors in a non-conventional manner. Instead of inhibiting tumor cell division, as the most widely used medications do, the strategy consisted of hyperactivating oncogenic signaling by these cells to the point where they became stressed.

27 Jul 2024

Understanding the epigenetic regulation of hepatic stellate cells in NAFLD

Non-alcoholic fatty liver disease (NAFLD) has emerged as a leading cause of chronic liver disease worldwide, affecting approximately 38% of the global population from 2016 to 2019.

25 Jul 2024

Researchers identify two risk factors that indicate higher risk of aggressive prostate cancer

A recent European Urology Oncology study assessed the mortality risks, based on the Gleason score and clinical parameters, in patients with prostate cancer.

11 Jul 2024

Machine learning identifies cancer-driving mutations at CTCF binding sites

Researchers developed a machine learning tool, CTCF-INSITE, to identify mutational hotspots at persistent CTCF binding sites across various cancers, highlighting their role in genomic structure disruption and cancer progression.

7 Jul 2024

Stanford researchers uncover key to overcoming chemoresistance in pancreatic cancer

Pancreatic cancer is a particularly aggressive and difficult-to-treat cancer, in part because it is often resistant to chemotherapy.

4 Jul 2024

Modified form of chemotherapy before and after surgery enhances survival in pancreatic cancer patients

Patients with pancreatic cancer who received chemotherapy both before and after surgery experienced longer survival rates than would be expected from surgery followed by chemotherapy, according to a new study from researchers at Yale Cancer Center (YCC) and Yale School of Medicine.

20 Jun 2024

Study shows effectiveness of treating pancreatic cancer patients with chemotherapy before surgery

A new study published today in JAMA Network Open by an international cohort of researchers provides the latest data on the effectiveness of treating pancreatic cancer patients with chemotherapy (with or without radiation therapy) before surgery to remove a tumor.

19 Jun 2024