Adenosine News and Research

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Adenosine is a nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a ß-N9-glycosidic bond.

Researchers visualize protein machinery of respiration for the first time

Oxygen and sugar are the basis of life for animals, plants, fungi and many bacteria. The metabolic process called respiration makes it possible to convert food into energy for the cells.

31 Jan 2022

Study finds overexpression of 3 SARS-CoV-2 genes could globally compromise transcriptome of human pluripotent stem cell-derived cardiomyocytes

In a recent study, whole mRNA-seq was used to investigate the global effects of SARS-CoV-2 viral genes Nsp6, Nsp8, and M on the transcriptome of hPSC-CMs.

26 Jan 2022

Oral supplement appears to promote muscle endurance and mitochondrial health in humans

An oral supplement intended to stimulate a natural body process appears to promote muscle endurance and mitochondrial health in humans.

20 Jan 2022

Virus-like particles as delivery vehicles for gene-editing

Scientists deliver gene-editing proteins through the use of engineered virus-like particles, which mediated efficient base editing both in vitro and in vivo.

13 Jan 2022

Slight pH adjustment may turn a metabolic inhibiting drug into promising COVID-19 treatment

Mechanical engineering and materials science professor David Needham has shown that a slight increase in solution pH might be all it takes to turn a metabolic inhibiting drug, traditionally used to treat gut parasites, into a promising prophylactic/preventative nasal spray and early treatment throat spray for COVID-19.

7 Jan 2022

New insights into how tiny bacteria from the environment have adapted to live inside humans

The microbes that live inside our mouths, collectively known as the oral microbiome, impact our overall health in many ways that are not yet fully understood.

4 Jan 2022

Researchers identify novel cancer markers in patients with aggressive prostate cancer

Prostate cancer is the most commonly diagnosed cancer in men and is among the top five causes of cancer-related death. In most cases, prostate cancer can be successfully treated but there is a group of patients who suffer an aggressive course and often fatal outcome.

22 Dec 2021

New oral pill for COVID-19 home treatment

As cases and hospitalizations continue to rise in many countries, new treatments are being sought to arrest the progression of the disease, preventing severe illness and death or disability. One such is the small molecule molnupiravir, the focus of a new research paper.

20 Dec 2021

New study shows how regular exercise protects against fatty liver disease

Exercise not only trains the muscles but can also prevent the development of fatty liver. A new study by the German Center for Diabetes Research, Helmholtz Munich and Tübingen University Hospital shows which molecular adaptations, in particular of the liver mitochondria, can be observed in this process.

20 Dec 2021

Newly discovered hormone may play a key role in the development of type 1 and type 2 diabetes

A newly discovered hormone named fabkin helps regulate metabolism and may play an important role in the development of both type 1 and type 2 diabetes, according to research led by the Sabri Ülker Center for Metabolic Research at Harvard T.H. Chan School of Public Health.

12 Dec 2021

New hormone may play a key role in the development of type 1 and type 2 diabetes

8 Dec 2021

Error rate of bacterial DNA polymerase is consistently higher under microgravity, study shows

On 22 May 2019, scientists from Queen's University boarded a modified Falcon 20 aircraft at Ottawa airport. Scheduled was a 'vomit comet' flight, where the plane repeatedly climbs to 8km in a steep parabola, alternating with a descent in freefall.

29 Nov 2021

Fast evolution of SARS-CoV-2 driven by extensive RNA deamination by host cells

A new study proposed that the RNA structure and the genome component may serve as an important basis of different deamination spectrums in SARS-CoV-2.

7 Nov 2021

Study provides a specific target to tackle breast cancer relapse

Molecular targets for therapies that could prevent breast cancer recurrence have been identified by a group of German, Norwegian and British scientists who analyzed tumour cells that proved resistant to the original treatment.

25 Oct 2021

Improper Z-RNA recognition contributes to pathogenesis of Aicardi-Goutières syndrome

Like DNA, RNA molecules contain information through unique combinations of four different nucleotides. However, through a molecular process called RNA editing, chemical changes can be made to adenosine nucleotides that convert them to a nucleotide called inosine by enzymes known as adenosine deaminases (ADARs).

21 Oct 2021

Adenosine News and Research

Further Reading

Researchers visualize protein machinery of respiration for the first time

Study finds overexpression of 3 SARS-CoV-2 genes could globally compromise transcriptome of human pluripotent stem cell-derived cardiomyocytes

Oral supplement appears to promote muscle endurance and mitochondrial health in humans

Virus-like particles as delivery vehicles for gene-editing

Slight pH adjustment may turn a metabolic inhibiting drug into promising COVID-19 treatment

New insights into how tiny bacteria from the environment have adapted to live inside humans

Researchers identify novel cancer markers in patients with aggressive prostate cancer

New oral pill for COVID-19 home treatment

New study shows how regular exercise protects against fatty liver disease

Newly discovered hormone may play a key role in the development of type 1 and type 2 diabetes

New hormone may play a key role in the development of type 1 and type 2 diabetes

Error rate of bacterial DNA polymerase is consistently higher under microgravity, study shows

Fast evolution of SARS-CoV-2 driven by extensive RNA deamination by host cells

Study provides a specific target to tackle breast cancer relapse

Improper Z-RNA recognition contributes to pathogenesis of Aicardi-Goutières syndrome

New discovery can pave the way to better diagnostics and therapeutics for asthma and COPD

Infrared light therapy may potentially benefit people with dementia

The biochemical mechanisms of remdesivir-mediated RNA synthesis inhibition

UC Davis researchers publish the first atlas of metabolites in the mouse brain

Researchers report long-lasting effects of gene therapy in children with deadly immune disorder

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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