Adjuvant Therapy News and Research

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Adjuvant Therapy is treatment given after the primary treatment to increase the chances of a cure. Adjuvant therapy may include chemotherapy, radiation therapy, hormone therapy, or biological therapy.

UAlberta researchers find strong clues to underlying cause of HIV-associated neurocognitive disorders

UAlberta researchers believe they now have a clearer picture of why people living with HIV so commonly suffer from dementia and other neurocognitive disorders.

20 Jul 2017

FDA approves first extended adjuvant therapy to lower risk of breast cancer recurrence

The U.S. Food and Drug Administration today approved Nerlynx (neratinib) for the extended adjuvant treatment of early-stage, HER2-positive breast cancer.

18 Jul 2017

Lymph node removal may not be needed for all melanoma patients, study finds

Many patients with melanoma need a sentinel-lymph-node biopsy to determine if cancer cells have spread there, but a positive finding doesn't mean all the lymph nodes in the area must be removed, according to new international study.

17 Jul 2017

Adherence to NCCN Guidelines spares breast cancer patients from unnecessary tests

According to SEER data, more than 260,000 women were diagnosed with breast cancer in the United States in 2016, most of whom were diagnosed with early-stage (stage I or II) disease.

21 Jun 2017

Adding a second HER2-targeted treatment may improve outcomes for some women with breast cancer

A phase III clinical trial of 4,805 women with HER2-positive breast cancer suggests adding a second HER2 targeted medicine, pertuzumab (Perjeta), to standard of care trastuzumab (Herceptin) after surgery may help, although the benefit is modest.

6 Jun 2017

Study shows effectiveness of 3 months of chemotherapy in colon cancer patients after surgery

After surgery for lymph-node positive colon cancer (stage III), some patients may only need half of the long-standing standard course of chemotherapy.

5 Jun 2017

Targeted therapy appears to be more effective in preventing lung cancer recurrence

The targeted therapy gefitinib appears more effective in preventing recurrence after lung cancer surgery than the standard of care, chemotherapy.

18 May 2017

ASTRO issues new clinical guideline for management of oropharyngeal cancer with radiation therapy

The American Society for Radiation Oncology today issued a new clinical guideline for the management of oropharyngeal cancer.

17 Apr 2017

Study shows um-PEA as safe and efficacious adjuvant treatment for advanced PD patients

Parkinson disease (PD) is a long-term degenerative disorder of the central nervous system that mainly affects the motor system.

12 Apr 2017

Study reveals promising therapeutic approach that can be beneficial for older melanoma patients

Scientists at The Wistar Institute have shown that an anti-diabetic drug can inhibit the growth of melanoma in older patients by activating an anti-aging gene that in turn inhibits a protein involved in metastatic progression and resistance to targeted therapies for the disease.

24 Feb 2017

Chemotherapy prior to surgery could improve prognosis in African-American breast cancer patients

Administering chemotherapy to African-American breast cancer patients prior to surgery could improve their prognosis and survival rates from the disease, according to a new study.

20 Jan 2017

Brain metastasis persists in women with HER2-positive breast cancer despite new targeted therapies

While new targeted treatments developed across the past two decades have led to dramatic survival improvements for women with HER2-positive metastatic breast cancer, University of North Carolina Lineberger Comprehensive Cancer Center researchers and collaborators report that rates of breast cancer brain metastasis for women with this disease have not substantially declined.

7 Dec 2016

Study finds many parents agree to use of placebos in children

Placebos are essential in any controlled clinical trial, providing a yardstick against which the test drug is measured.

15 Nov 2016

High out-of-pocket costs, rather than race/ethnicity, may impact adjuvant endocrine therapy adherence

High out-of-pocket costs, rather than race or ethnicity, are responsible for disparities associated with adherence to adjuvant endocrine therapy, according to a new study from researchers at The University of Texas Health Science Center at Houston (UTHealth) School of Public Health.

1 Nov 2016

Immune checkpoint inhibitor as adjuvant therapy improves overall survival in patients with stage III melanoma

Ipilimumab as adjuvant therapy significantly improves overall survival in patients with high risk stage III melanoma, according to the EORTC 18071 phase III trial results presented for the first time today at the ESMO 2016 Congress in Copenhagen.

8 Oct 2016

ASTRO clinical practice statement outlines recommendations to customize treatment for rectal cancer

The American Society for Radiation Oncology recently issued a new clinical practice statement, "Appropriate Customization of Radiation Therapy for Stage II and III Rectal Cancer: An ASTRO Clinical Practice Statement Using the RAND/UCLA Appropriateness Method."

21 Jul 2016

Adjuvant Therapy News and Research

UAlberta researchers find strong clues to underlying cause of HIV-associated neurocognitive disorders

FDA approves first extended adjuvant therapy to lower risk of breast cancer recurrence

Lymph node removal may not be needed for all melanoma patients, study finds

Adherence to NCCN Guidelines spares breast cancer patients from unnecessary tests

Adding a second HER2-targeted treatment may improve outcomes for some women with breast cancer

Study shows effectiveness of 3 months of chemotherapy in colon cancer patients after surgery

Targeted therapy appears to be more effective in preventing lung cancer recurrence

ASTRO issues new clinical guideline for management of oropharyngeal cancer with radiation therapy

Study shows um-PEA as safe and efficacious adjuvant treatment for advanced PD patients

Study reveals promising therapeutic approach that can be beneficial for older melanoma patients

Chemotherapy prior to surgery could improve prognosis in African-American breast cancer patients

Brain metastasis persists in women with HER2-positive breast cancer despite new targeted therapies

Study finds many parents agree to use of placebos in children

High out-of-pocket costs, rather than race/ethnicity, may impact adjuvant endocrine therapy adherence

Immune checkpoint inhibitor as adjuvant therapy improves overall survival in patients with stage III melanoma

ASTRO clinical practice statement outlines recommendations to customize treatment for rectal cancer

Study finds low rates of baseline BMD testing among older women with breast cancer

Whole-genome omics data can improve accuracy of breast cancer survival predictions

Itaconate can suppress pro-inflammatory activity of macrophages

Researchers identify lymphatic endothelial lineage that shows potential for new anti-cancer treatment

Bionic vision restoration: could future technologies restore sight?

Preclinical research using 1 Tesla desktop MRI

Understanding the rise in NTM infections

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