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Immunological factors associated with impaired BNT162b2 mRNA vaccine response in older adults

A new study posted to the pre-print server medRxiv* investigated the significant immune alterations concerning SARS-CoV-2 specific innate and adaptive immunity associated with a lower BNT162b2 mRNA vaccine response in older individuals.

10 Jan 2022

SARS-CoV-2 levels decrease when human SIRT5 is deleted or inhibited

Researchers examine the role of human sirtuin 5 (SIRT5) in SARS-CoV-2 infection.

10 Jan 2022

Poor cognition may be part of normality in older age, research says

At the first sign of cognitive trouble, people often worry Alzheimer's disease is forthcoming. But poor cognition can be part of the spectrum of normality in older age, according to new research published in JNeurosci.

10 Jan 2022

Improving air quality may reduce dementia risk in older women

Improving air quality appears to slow cognitive decline and reduce the risk of developing dementia in older women living in the U.S., according to a new study by researchers from the Keck School of Medicine of USC.

10 Jan 2022

Black-owned hospice seeks to bring greater ease in dying to Black families

This time, it didn’t take much persuading for Mary Murphy to embrace home hospice. When her mother was dying from Alzheimer’s disease in 2020, she had been reluctant until she saw what a help it was. So when her husband, Willie, neared the end of his life, she embraced hospice again.

10 Jan 2022

Researchers identify factors at midlife linked with 10-year declines in women's physical health

Among 55-year-old women, factors such as higher body mass index, smoking, osteoarthritis, depressive symptoms and more were associated with clinically important declines in physical health 10 years later.

9 Jan 2022

Study reveals how the brain’s blue spot shapes selective attention

How can we shift from a state of inattentiveness to one of highest attention? The locus coeruleus, literally the "blue spot," is a tiny cluster of cells at the base of the brain.

7 Jan 2022

ED visits for pediatric poisonings increased nine times following cannabis legalization

Ontario saw nine times more emergency department (ED) visits per month for cannabis poisonings in young children under the age of 10 after Canada legalized recreational cannabis, according to a study published in JAMA Network Open.

7 Jan 2022

Physical activity may help boost synaptic functioning in older adults

When elderly people stay active, their brains have more of a class of proteins that enhances the connections between neurons to maintain healthy cognition, a UC San Francisco study has found.

7 Jan 2022

Study estimates the global prevalence of dementia in 2050

The number of adults (aged 40 years and older) living with dementia worldwide is expected to nearly triple, from an estimated 57 million in 2019 to 153 million in 2050, due primarily to population growth and population aging.

6 Jan 2022

Study reinforces the link between microglia and some cases of brain disease

Certain subtle differences in DNA sequences are known to raise the chances a person may develop Alzheimer's or Parkinson's disease.

6 Jan 2022

Model of neuromuscular junction could accelerate new treatments for neuromuscular diseases

The neuromuscular junction-;where nerves and muscle fibers meet-;is an essential synapse for muscle contraction and movement.

6 Jan 2022

Researchers identify how a critical schistosomiasis drug works on the molecular level

Independent teams from Texas Biomedical Research Institute and the Medical College of Wisconsin have published two papers in Science Translational Medicine identifying how the only approved drug to treat schistosomiasis, a widespread parasitic worm infection, works on the molecular level.

6 Jan 2022

Aging News and Research

Immunological factors associated with impaired BNT162b2 mRNA vaccine response in older adults

SARS-CoV-2 levels decrease when human SIRT5 is deleted or inhibited

Poor cognition may be part of normality in older age, research says

Improving air quality may reduce dementia risk in older women

Black-owned hospice seeks to bring greater ease in dying to Black families

Researchers identify factors at midlife linked with 10-year declines in women's physical health

Study reveals how the brain’s blue spot shapes selective attention

ED visits for pediatric poisonings increased nine times following cannabis legalization

Physical activity may help boost synaptic functioning in older adults

Study estimates the global prevalence of dementia in 2050

Study reinforces the link between microglia and some cases of brain disease

Model of neuromuscular junction could accelerate new treatments for neuromuscular diseases

Researchers identify how a critical schistosomiasis drug works on the molecular level

Optical sensing can address unmet clinical needs in orthopedic surgery

Salk professor receives $1.2 million from Larry L. Hillblom Foundation for diabetes research

A new paradigm is needed: Top experts question the value of advance care planning

Drugs that block mineralocorticoid receptor may help protect bone cells during aging

A closer look at the relationship between COVID-19 and Alzheimer’s disease

New Potocsnak Longevity Institute aims to extend human 'healthspan'

As covid hits nursing homes’ finances, town residents fight to save Alzheimer’s facility

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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