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New single probe method provides PCR-free detection of microRNA linked to liver toxicity

Quanterix Corporation, a company digitizing biomarker analysis with the goal of advancing the science of precision health, and DestiNA Genomics Ltd, a manufacturer of patented reagents for nucleic acid detection, today announced that PLOS ONE has published a proof-of-concept single probe method for detecting microRNA biomarkers associated with liver toxicity.

6 Jul 2017

Researchers link intestinal fungi to increased risk of death in patients with alcoholic liver disease

Liver cirrhosis is the 12th leading cause of mortality worldwide and approximately half of those deaths are due to alcohol abuse.

23 May 2017

Researchers develop smart genetic reference library for locating disease-causing mutations

Researchers at Hiroshima University have developed a smart genetic reference library for locating and weeding out disease-causing mutations in populations.

3 Mar 2017

Researchers aim to develop sustained and controllable insulin release system for treatment of diabetes

The prevalence of diabetes has grown around the world over the past three decades. In 2016, the World Health Organization estimated that 422 million people had the disease as the rate of obesity also increased.

27 Feb 2017

NASPGHAN clinical practice guidelines recommend screening test for NAFLD in obese children

A screening test for non-alcoholic fatty liver disease (NAFLD)--a serious condition that may have lifelong health consequences--is recommended for all obese children aged nine to eleven years, according to clinical practice guidelines developed by the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition and published in the Journal of Pediatric Gastroenterology and Nutrition.

1 Dec 2016

Scientists develop safe, highly efficient method to improve searching of new germicides

Scientists from the Lomonosov Moscow State University in cooperation with colleagues have worked out a safe, not that expensive and highly efficient method, which allows to speed up and improve searching of new germicides.

29 Nov 2016

Combination treatment with CDK4/6 inhibitor improves progression-free survival in HR+ breast cancer patients

The addition of the CDK4/6 inhibitor ribociclib to letrozole therapy significantly improves progression-free survival in postmenopausal women with hormone receptor-positive advanced breast cancer, researchers reported today at the ESMO 2016 Congress in Copenhagen.

8 Oct 2016

Crick researchers find promising target for new tuberculosis drugs

Scientists led by Dr Luiz Pedro Carvalho at the Francis Crick Institute in London have found a promising new target in the search for new tuberculosis drugs. In the process, they say they've proven the strengths of a new research technique called metabolomics.

20 Sep 2016

Researchers find high levels of neurotoxins linked to Alzheimer's, ALS in fins and muscles of sharks

In a new study, University of Miami scientists found high concentrations of toxins linked to neurodegenerative diseases in the fins and muscles of 10 species of sharks.

30 Aug 2016

Low selenium levels linked to liver cancer risk? An interview with Dr David Hughes

Food provides us with a variety of substances we need to maintain life. These substances are essential nutrients and are classified as macronutrients (water, protein, fats, and carbohydrates) and micronutrients (vitamins and minerals).

22 Aug 2016

Pancreatic cancer cells find alternative source of nutrition to avoid starvation

Pancreatic cancer cells avert starvation in dense tumors by ordering nearby support cells to supply them with an alternative source of nutrition.

11 Aug 2016

New diagnostic model may become cheaper and easier alternative to screen for NAFLD

Researchers have developed a diagnostic model that is highly predictive of nonalcoholic fatty liver disease (NAFLD).

13 Jul 2016

TDF reduces vertical HBV transmission

The mother-to-child transmission of hepatitis B virus is reduced with tenofovir disoproxil fumarate treatment during the third trimester in pregnant chronic HBV patients with a high viral load, show the findings of a trial conducted in China.

4 Jul 2016

New technology could help deliver treatments for brain injuries

A new study led by scientists at the Sanford Burnham Prebys Medical Discovery Institute describes a technology that could lead to new therapeutics for traumatic brain injuries. The discovery, published today in Nature Communications, provides a means of homing drugs or nanoparticles to injured areas of the brain.

29 Jun 2016

'Simple' model predicts PegIFN response in chronic HBV

Chinese researchers have developed a scoring system based on hepatitis B virus-related clinical parameters to predict response to pegylated-interferon in chronic HBV patients.

23 Jun 2016

HCC predictors identified for chronic HBV patients with newly diagnosed cirrhosis

In patients with chronic hepatitis B virus infection who have been newly diagnosed with cirrhosis, the risk of hepatocellular carcinoma development can be ascertained using several clinical and molecular factors, study findings indicate.

23 Jun 2016

Zinbryta gets FDA approval for treating adults with relapsing forms of MS

The U.S. Food and Drug Administration today approved Zinbryta (daclizumab) for the treatment of adults with relapsing forms of multiple sclerosis (MS). Zinbryta is a long-acting injection that is self- administered by the patient monthly.

28 May 2016

WFA+-M2BP levels linked to liver fibrosis, HCC progression in chronic HBV

Japanese researchers have found that serum levels of glycosylated Wisteria floribunda agglutinin-positive Mac-2 binding protein are a useful marker of not only the degree of liver fibrosis, but also progression to hepatocellular carcinoma in patients with chronic hepatitis B virus infection.

27 Apr 2016

Serum marker may flag liver fibrosis in chronic HBV

Serum levels of Wisteria floribunda agglutinin-positive Mac-2-binding protein may reflect the severity of liver fibrosis in patients with chronic hepatitis B virus infection, say researchers.