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Mucosal IgA fused nanobody as a non-invasive, cost-effective prophylaxis and therapeutic option against major SARS-CoV-2 variants

Researchers from the United States developed an affordable, non-invasive, inhalable prophylactic treatment consisting of immunoglobulin (Ig) A fused nanobodies against the SARS-CoV-2 Omicron variant.

2 Dec 2022

Researchers uncovers a link between D-amino acids and severe viral infection

Just as bricks are key components in constructing a building, molecules known as amino acids are essential components in constructing proteins in the body.

28 Nov 2022

Honey improves key measures of health, including blood sugar and cholesterol levels

Researchers look to better understand the impact of honey on mitigating certain cardiometabolic risk factors.

20 Nov 2022

Prevalence and severity of liver enzyme alterations in COVID-19 and association with patient-centered outcomes

Researchers examined the prevalence of changes in liver enzymes in COVID-19.

15 Nov 2022

Structure-directed mutagenesis produces thermostable SARS-CoV-2 spike protein trimers with potential vaccine booster applications

Researchers investigated the change in the stability, antigenicity, and protein expression of the SARS-CoV-2 spike protein trimer using structure-directed mutagenesis to alter a cavity in the core of the spike protein.

14 Nov 2022

Researchers identify 55 broadly reactive monoclonal antibodies to betacoronaviruses

In a recent study published in the journal Cell Host & Microbe, researchers pursued novel approaches that could help find monoclonal antibodies (mAbs) broadly targeting coronaviruses (CoVs), especially genera beta CoVs.

8 Nov 2022

Weekly weight loss drug reduces BMI in teens

Researchers report that a weekly dose of semaglutide led to a significant BMI reduction in adolescents.

3 Nov 2022

Study reveals the molecular mechanisms of dynamic activation of DNMT1 by H3Ub2

This study is led by Dr. Na Yang (State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Key Laboratory of Medical Data Analysis and Statistical Research of Tianjin, Nankai University), and Dr. Bing Zhu (National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Science).

28 Oct 2022

What are the predictors of new-onset diabetes in hospitalized COVID-19 patients?

Researchers evaluated the incidence and predictors of new-onset diabetes (NOD) in patients hospitalized with coronavirus disease 2019 (COVID-19).

18 Oct 2022

Motif-based SARS-CoV-2 protein-human protein interactions as potential antiviral target sites

Researchers performed a ProP-PD (proteomic peptide phage display) analysis to identify peptides from intrinsically disordered human (host) proteome regions that bind with SARS-CoV-2 genome-encoded folded protein domains (PDs).

13 Oct 2022

MIT researchers use new technique to gather insight into repetitive protein sequences

About 70 percent of all human proteins include at least one sequence consisting of a single amino acid repeated many times, with a few other amino acids sprinkled in. These "low-complexity regions" are also found in most other organisms.

13 Sep 2022

Study investigates the efficacy and safety of selpercatinib in a diverse group of patients

The highly selective RET inhibitor selpercatinib was well-tolerated and achieved durable objective responses across multiple tumor types in the Phase I/II LIBRETTO-001 trial, according to researchers from The University of Texas MD Anderson Cancer Center.

13 Sep 2022

Alanine News and Research

Mucosal IgA fused nanobody as a non-invasive, cost-effective prophylaxis and therapeutic option against major SARS-CoV-2 variants

Researchers uncovers a link between D-amino acids and severe viral infection

Honey improves key measures of health, including blood sugar and cholesterol levels

Prevalence and severity of liver enzyme alterations in COVID-19 and association with patient-centered outcomes

Structure-directed mutagenesis produces thermostable SARS-CoV-2 spike protein trimers with potential vaccine booster applications

Researchers identify 55 broadly reactive monoclonal antibodies to betacoronaviruses

Weekly weight loss drug reduces BMI in teens

Study reveals the molecular mechanisms of dynamic activation of DNMT1 by H3Ub2

What are the predictors of new-onset diabetes in hospitalized COVID-19 patients?

Motif-based SARS-CoV-2 protein-human protein interactions as potential antiviral target sites

MIT researchers use new technique to gather insight into repetitive protein sequences

Study investigates the efficacy and safety of selpercatinib in a diverse group of patients

Phase I/II LIBRETTO-001 trial: RET inhibitor achieves durable objective responses across multiple tumors

Exposure to blue light may accelerate aging

SARS-CoV-2 mutational spectra based on reconstructed phylogenetic tree

Surprising culprit contributes significantly to the brain destruction after stroke or TBI

What is the impact of COVID-19 on maternal, fetal, and neonatal characteristics?

Review of natural products with promising anti-SARS-CoV-2 potential

Scientists conduct comparative analysis of monkeypox virus profilin-like proteins and human profilin proteins

Researchers unravel the mechanism of teixobactin at the atomic level

E-Cigarettes and Ethanol: A forensic Perspective on Vaping

Understanding Consumer-Consented Data to Optimize Digital Health Programs

The Future is Wearable: Advancing Human Health Through Portable Spectroscopy

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