Aldosterone is a steroid hormone made by the adrenal cortex (the outer layer of the adrenal gland). It helps control the balance of water and salts in the kidney by keeping sodium in and releasing potassium from the body. Too much aldosterone can cause high blood pressure and a build-up of fluid in body tissues. Aldosterone is a type of mineralocorticoid hormone.
A recent study posted to the medRxiv* preprint server investigated the association of renin-angiotensin-aldosterone system (RAAS)-mediated hypertension (HT) with coronavirus disease 2019 (COVID-19).
Patients taking renin-angiotensin-aldosterone system inhibitor (RAASi) medications for heart failure had significantly lower blood potassium levels when taking patiromer—a drug that helps to prevent the body from absorbing too much potassium—compared with a placebo, in a study presented at the American College of Cardiology's 71st Annual Scientific Session.
Just as a water filtration system acts to filter contaminants from the water you drink, your kidneys act to filter waste and excess fluid from your blood.
Researchers conducted an umbrella review and meta-analysis of the RAAS inhibitors' impact on COVID-19 clinical outcomes.
A new study reports finds very low aldosterone levels in a subset of COVID-19 patients.
A new study looks at the molecular level inhibition of the protective CFTR gene by the SARS-CoV-2 spike protein.
In this study, researchers described the effect of significant changes of small RNAs in the post-transcriptional regulatory network.
A study published in the journal Nature Reviews Urology discusses the impact of coronavirus disease 2019 (COVID-19) on male fertility.
Aspirin use is associated with a 26% raised risk of heart failure in people with at least one predisposing factor for the condition.
A review published in Chemo-Biological Interactions has focused on the prevalence of COVID-19 in CVD patients associated with ACE2 mechanisms.
Six-month outcomes from the randomized RADIANCE-HTN TRIO Trial comparing endovascular ultrasound renal denervation (RDN) to a sham procedure for treatment-resistant hypertension (HTN) found that the addition of a pharmacologic intervention led to further blood pressure reductions after RDN with a smaller increase in additional medications prescribed and less use of diuretics.
Another difference between females and males appears to be a key mechanism in how they become hypertensive, scientists say, and consequently which antihypertensives should be most effective for them.
A new review article investigates the clinical and viral characteristics, pathogenesis, as well as human genetic basis associated with COVID-19.
In a new study, researchers investigate a number of drugs that are believed to potentially worsen outcomes in patients with COVID-19.
An international study, led by researchers from Queen Mary University of London and St Bartholomew's Hospital, has found a unique pair of gene variants that causes sudden onset high blood pressure in pregnant women.
Currently, patients with HFpEF have high risk of morbidity and mortality, but there is no effective measure for evaluating the prognosis.
People who are just beginning treatment for high blood pressure can benefit equally from two different classes of medicine - angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) - yet ARBs may be less likely to cause medication side effects, according to an analysis of real-world data published today in Hypertension, an American Heart Association journal.
In a recent review in Environmental Science and Pollution Research, Italian researchers focused on “the evidence that correlates the degree and type of pollution with the increased susceptibility of many countries to this pandemic and proposes human semen as an early marker of the environmental health and the general health of individuals.” Their observations are based on a robust body of experimental evidence.
Thus, the need to stratify the risk of severe or critical disease in patients presenting with SARS-CoV-2 infection remains a crying necessity. A new preprint research paper posted to the medRxiv server discusses the relationship between severe disease and pre-existing susceptibility to clots and other diseases of the cardiovascular system.
Obesity and a high-salt diet are both bad for our hearts but they are bigger, seemingly synergistic risks for females, scientists report.