Aldosterone is a steroid hormone made by the adrenal cortex (the outer layer of the adrenal gland). It helps control the balance of water and salts in the kidney by keeping sodium in and releasing potassium from the body. Too much aldosterone can cause high blood pressure and a build-up of fluid in body tissues. Aldosterone is a type of mineralocorticoid hormone.
Researchers at the Radboud University Medical Center seem to have found an essential mechanism in the disease process of COVID-19, which has so far been overlooked.
A new opinion piece published in the journal Circulation Research in April 2020 defends the use of antihypertensive drugs called ACE inhibitors and ARBs in patients with pandemic viral pneumonia called COVID-19.
The COVID-19 pandemic has forced clinicians and academicians to intensive research to find evidence for many conventional therapies. A new round-up editorial published in the journal Cardiovascular Research in April 2020 summarizes the current clinical grounds for and against the use of the commonly used angiotensin axis inhibitors in patients with COVID-19.
Emerging concerns that common antihypertensive treatment approaches with angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) – jointly known as renin-angiotensin-aldosterone system (RAAS) inhibitors – may exert a negative effect in COVID-19 patients are not grounded in scientific evidence, as reported by researchers in a recent review article published in Mayo Clinic Proceedings journal.
Common drugs used in high blood pressure, heart failure, and diabetic patients with kidney damage, including angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs), could be protective in patients with COVID-19.
In pulmonary arterial hypertension, high blood pressure in the lungs' arteries causes the heart to work extra hard to pump blood to the lungs and around the rest of the body.
New collaborative research at Queen's University Belfast and Victoria University, Melbourne, Australia aims to better understand the link between meditation and improved mental health outcomes.
A new study published in January 2020 in the European Journal of Preventive Cardiology shows that burnout could really cause your heart to fail as a result of an abnormal heart rhythm called atrial fibrillation (AF).
When the adrenal gland produces too much aldosterone, this often leads to high blood pressure and kidney damage (hyperaldosteronism). It has only recently emerged that several patients harbor a mutation in the gene for the ClC-2 chloride channel.
A study published in the International Journal of Molecular Sciences, as part of a special issue “Heart Failure: From Molecular Basis to Therapy”, in August 2019, shows that aliskiren, a drug approved by the US Food and Drug Administration (FDA), can improve survival for over 5 years, on average, and enhance life quality in patients who have been correctly diagnosed with heart failure.
Blocking the mineralocorticoid receptor (MR)- a protein that helps maintain normal levels of salt and water in the body- in immune cells may help reduce the risk of heart attack and stroke by improving blood vessel health.
Aldosterone is a steroid hormone important to the regulation of salt, fluid and potassium in the body.
New research suggests that an individualized probiotic therapy regimen may improve symptoms of gout, gout-related kidney disease and other signs of metabolic syndrome.
A team of researchers of MedUni Vienna working with the endocrinologists and gender physicians Michael Leutner and Alexandra Kautzky-Willer as well the division for complex statistical systems with Peter Klimek and Caspar Matzhold in cooperation with Complexity Science Hub Vienna were able to demonstrate for the first time a connection between the potency and dosage of statins with a diagnosis of osteoporosis, based on several million data sets.
International physiologists and researchers studying the kidney, high blood pressure and related medical conditions will convene next week at the American Physiological Society (APS) Aldosterone and ENaC in Health and Disease: The Kidney and Beyond Conference in Estes Park, Colo.
AdrenoGenital Syndrome (AGS) encompasses a group of inherited metabolic disorders caused by a disruption in steroid hormone production in the adrenal cortex.
Heart failure with preserved ejection fraction (HFpEF) is a common condition, affecting millions of people and resulting in significant illness and death. No effective treatments have been developed for this condition.
The first ever medication to treat age-related hearing loss could potentially receive FDA approval through a comprehensive study being conducted at the University of South Florida.
Higher doses of spironolactone, a diuretic (water pill), can prevent the need for dialysis in selected heart failure patients, a UT Health San Antonio study found.
Alport syndrome is a hereditary type IV collagen disease that leads to progressive proteinuria, renal fibrosis, and kidney failure.