Allele News and Research

RSS

Gene therapy can reduce long-term drinking among rodents

Just as the risk of developing alcoholism is strongly influenced by genetic factors, mutations in gene coding - such as the aldehyde dehydrogenase (ALDH2*2) allele - also appear to protect against the risk.

4 Jan 2008

Gene variation increases risk of liver tumor in patients with cirrhosis

A particular gene variation appears to significantly increase the risk that individuals with cirrhosis of the liver will go on to develop hepatocellular carcinoma (HCC), a liver tumor that is the third leading cause of cancer death.

2 Jan 2008

Variant of COMT gene linked to impulsive decisions

People with clinical addictions know first-hand the ravages the disease can take on almost every aspect of their lives.

28 Dec 2007

Brain imaging shows there may be a cognitive difference in people with addictions

Scientists have for the first time identified brain sites that fire up more when people make impulsive decisions.

28 Dec 2007

Role of genetics in multiple sclerosis

New research announced this week has found an association between certain genes and the severity of multiple sclerosis (MS).

10 Dec 2007

Genetic differences point to ethnic and racial disparities in colorectal cancer risk

Risk of developing colorectal cancer is known to differ across ethnic and racial groups, and now an analysis of 26 studies, involving over 25,000 participants shows that some of these disparities might be explained by distinct patterns of genetic inheritance.

29 Nov 2007

Study of Mexican Americans shows that polymorphisms of the CYP2E1 gene enhance susceptibility to alcoholism

Mexican Americans make up 66 percent of the U.S. Hispanic population and, when compared to other ethnic groups, show high rates of heavy drinking and alcohol-related problems.

27 Nov 2007

Why are males in evolutionary overdrive even though they have essentially the same genes as females?

The observation that males evolve more quickly than females has been around since 19th century biologist Charles Darwin noted the majesty of a peacock's tail feather in comparison with the plainness of the peahen's.

15 Nov 2007

ADH2 and ALDH2 are associated with esophageal cancer

As the seventh leading cause of cancer death worldwide, the occurrence of esophageal cancer varies by geographic area, ethnic group and gender.

1 Nov 2007

One in seven Americans over the age of 70 suffers from dementia

About 3.4 million people, or 13.9 percent of the population age 71 and older, have some form of dementia, the study found. As expected, the prevalence of dementia increased dramatically with age, from five percent of those aged 71 to 79 to 37.4 percent of those age 90 and older.

31 Oct 2007

Not just humans benefit from animal biotechnology

Laboratory animals are the source of major discoveries and breakthroughs in biology, not just in tackling disease but also unravelling fundamental molecular processes.

25 Oct 2007

Genetics of alcoholism

While both environmental and genetic factors contribute to the risk of developing alcohol dependence, it is believed to be a largely heritable – 52 to 64 percent – disease.

24 Oct 2007

New explanation for evolutionary changes in genetic sex-determination systems

In animals with separate sexes, embryos commit to becoming male or female at an early stage.

22 Oct 2007

Evidence of same-sex mating in nature

Cryptococcus neoformans is a major cause of fungal meningitis in predominantly immunocomprised individuals.

19 Oct 2007

Discovery of way to match pathogens to their antibodies

The search for a vaccination against HIV has been in progress since 1984, with very little success.

15 Oct 2007

People with lower dopamine levels eat more

Science has found one likely contributor to the way that some folks eat to live and others live to eat.

15 Oct 2007

Dopamine levels and appetite

Science has found one likely contributor to the way that some folks eat to live and others live to eat.

15 Oct 2007

Schizophrenia candidate genes affect even healthy individuals

Do gene variants that convey risk for schizophrenia affect apparently healthy individuals? Although these genes are present in every human, individuals may have different versions of these genes, called alleles.

1 Oct 2007

Schizophrenia candidate genes affect even healthy individuals

27 Sep 2007

Mutation of the COX2 gene can double or treble a woman's risk of ovarian cancer

Researchers in Portugal have discovered that a specific mutation of the COX2 gene seems to play a role in the onset of ovarian cancer, increasing women's susceptibility to developing the disease.

26 Sep 2007