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African Americans more likely to carry genetic variants known to stimulate inflammatory response

Specific variants in genes that encode proteins regulating inflammation may hold a key to explaining a host of disease processes known to cause increased risk of illness and death among African Americans, according to a study from the University of Pittsburgh's Graduate School of Public Health (GSPH).

1 Dec 2004

Brain imaging shows differences in people at risk for Alzheimer's

Using brain imaging, researchers at Columbia University Medical Center (CUMC) have found clear differences in brain function between healthy people who carry a genetic risk factor for Alzheimer's disease and those who lack the factor.

20 Nov 2004

The brain's dopamine system is key to alcoholism

Among the many genes that may contribute to an individual's susceptibility to alcoholism, those in the dopamine system are of special interest because addictive substances can activate this system.

14 Nov 2004

Researcher looks for clues to degenerative, deadly disease called Ataxia-telangiectasia

Few have heard of the degenerative, deadly disease called Ataxia-telangiectasia (A-T) but a University of Alberta researcher is hoping to provide clues to this mysterious disorder.

23 Sep 2004

Studies of human genetic variation have found strong evidence for the action of natural selection

One of the most comprehensive studies of the forces that have shaped patterns of human genetic variation has found strong evidence for the action of natural selection, which may help explain why certain people are at risk for a variety of conditions and others are not.

8 Sep 2004

Drinking alcohol regularly in your 40's increases risk of mild cognitive impairment

People in their 40's who drink alcohol regularly could be increasing their risk of mild cognitive impairment, a precursor to dementia and Alzheimer's. The claim is reported in the current issue of the British Medical Journal.

2 Sep 2004

Parental human leukocyte antigen genes linked to preterm delivery

The transmission of Human Leukocyte Antigen (HLA) genes may play a significant role in the risk of preterm delivery, according to a study in the September issue of Obstetrics and Gynecology.

31 Aug 2004

Genetic mutation link to sudden infant death syndrome

Researchers at Rush University Medical Center, and colleagues at the University of Pittsburgh have identified mutations in genes pertinent to the autonomic nervous system among babies who died of sudden infant death syndrome (SIDS) that might explain why they died.

21 Aug 2004

Significant advance in the understanding of the hepatitis C virus (HCV)

Researchers have made a significant advance in the understanding of the hepatitis C virus (HCV) by identifying new genetic factors associated with clearing the virus spontaneously without the necessity for additional treatment.

9 Aug 2004

Scientists create mice that don't gain weight, even when fed fat-laden, high calorie diets

By altering the expression of a single -- albeit different – gene, Drs. Roger Davis (UMASS Medical School, USA) and Ying-Hue Lee (Academia Sinica, Taiwan) have succeeded in creating two different strains of transgenic mice that don't gain weight, even when fed fat-laden, high calorie diets.

2 Aug 2004

Possible inherited component for lung cancer

Researchers have discovered a possible inherited component for lung cancer, a disease normally associated with external causes, such as cigarette smoking.

27 Jul 2004

A higher male susceptibility to disease has helped shape the evolution of social insect behavior

A pair of scientists has proposed a new model for behavioral development among social insects, suggesting that a higher male susceptibility to disease has helped shape the evolution of the insects' behavior.

24 May 2004

Apolipoprotein E (APOE) gene may increase the risk of Parkinson’s disease

One variant of the apolipoprotein E (APOE) gene may increase the risk of Parkinson’s disease, according to an analysis of research that will be presented at the American Academy of Neurology 56th Annual Meeting in San Francisco, Calif., April 24 – May 1, 2004.

27 Apr 2004