Amputations News and Research

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Bypass surgery linked to fewer amputations in people with severe peripheral artery disease

People with severe peripheral artery disease, or PAD, who received bypass surgery to improve blood flow to their legs and feet had 65 percent fewer repeat procedures and 27% fewer amputations than those who had minimally invasive procedures such as angioplasty and stenting, according to preliminary late-breaking research presented today at the American Heart Association's Scientific Sessions 2022.

7 Nov 2022

Open bypass surgery results in better outcomes for specific patients with severe form of peripheral artery disease

Performing open bypass surgery to restore circulation for people with a severe form of peripheral artery disease (PAD) – a condition that limits blood flow to the legs and feet – resulted in better outcomes for specific patients compared to a less-invasive procedure, a National Institutes of Health-supported clinical research trial has found.

7 Nov 2022

Proactive simple surgical procedure could be effective for treating diabetic foot ulcers

Performing proactive surgery to adjust the mechanics of the foot, appears to be effective to treat diabetic foot ulcers, a common and debilitating complication of diabetes, without the potential complications and at significantly lower cost compared to conservative management.

19 Sep 2022

Tight control of blood sugar in teens may help reduce diabetes-related brain damage

Tight control of blood sugar in teens with Type 1 diabetes may help reduce the disease's damaging effects on the brain, effects which have been shown even in younger children, according to a study published online today in Nature Communications.

30 Aug 2022

Study yields critical clues for successful inflammatory recovery

Inflammation is the body's first line of defense, occurring as droves of immune cells rush to the site of injury or acute illness to make repairs and stem further damage.

22 Aug 2022

They call it ‘tranq’ — and it’s making street drugs even more dangerous

Approaching a van that distributes supplies for safer drug use in Greenfield, Massachusetts, a man named Kyle noticed an alert about xylazine.

11 Aug 2022

Exercise that induces leg pain seems to be beneficial for people with peripheral artery disease

Walking for exercise at a pace that induced pain or discomfort improved walking ability among people with peripheral artery disease, or PAD, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

27 Jul 2022

People with severe brachial plexus injuries report less pain, more satisfaction after amputation

Reconstruction surgery may not work for some people with severe brachial plexus injuries, so they choose to undergo amputation.

30 Jun 2022

Microfluidics-enabled soft robotic prosthetics show promise to reduce skin ulcerations, pain in amputees

Every 30 seconds, a leg is amputated somewhere in the world due to diabetes. These patients often suffer from neuropathy, a loss of sensation in the lower extremities, and are therefore unable to detect damage resulting from an ill-fitting prosthesis, which leads to the amputation of a limb.

28 Jun 2022

Annual Wellness Visits associated with reduced risk of amputations in patients with diabetes

Patients with diabetes who participate in a free Annual Wellness Visit covered by Medicare are 36% less likely to need an amputation, a new study from University of Virginia School of Medicine researchers and their collaborators found.

15 Jun 2022

California wants to slash insulin prices by becoming a drugmaker. Can it succeed?

California is diving into the prescription drug business, attempting to achieve what no other state has done: produce its own brand of generic insulin and sell it at below-market prices to people with diabetes like Sabrina Caudillo.

7 Jun 2022

Disparities in major leg amputation and mortality for patients with diabetic foot ulcers

A new study published in JAMA Network Open aimed to identify how intersectionality among race, ethnicity, rurality, and neighborhood disadvantage can result in high risks of major leg amputations and death among Medicare beneficiaries who were hospitalized with diabetic foot ulcers.

24 Apr 2022

CR Forum to honor Cleveland Clinic researcher with a 2022 Top Ten Clinical Research Achievement Award

Paul Marasco, PhD, Associate Staff, Department of Biomedical Engineering at Cleveland Clinic, will be honored with a 2022 Top Ten Clinical Research Achievement Award by the Clinical Research Forum (CR Forum).

12 Mar 2022

Alkem signs license agreement with Harvard to develop, commercialize new technology for treating ischemic conditions

Alkem Laboratories Limited, an Indian multinational pharmaceutical company, has signed a license agreement with Harvard University's Office of Technology Development enabling Alkem to develop and commercialize a novel technology that may help meet the dire need for effective treatment of diabetic neuropathy, foot ulcers, peripheral arterial disease (PAD), and other injuries caused by vascular disease.

11 Feb 2022

Racial or ethnic group of patients with diabetes influences prognosis of the disease

Professor and researcher of the Faculty of Nursing and Podiatry of the UV, Yasmín Ezzatvar, together with researchers from other centers, concludes that the racial or ethnic group of patients with type 1 and 2 diabetes mellitus influences the prognosis of the disease, due to differences in mortality, risk of kidney disease or risk of cardiovascular disease.

15 Nov 2021

Albert Einstein College of Medicine wins new NIH funding to support diabetes research

Albert Einstein College of Medicine has received a five-year, $4 million grant from the National Institutes of Health to support the New York Regional Center for Diabetes Translation Research (NY-CDTR).

20 Oct 2021

Scientists link insulin resistance to increased risk of developing major depressive disorder

Stanford Medicine scientists have linked insulin resistance to an increased risk of developing a major depressive disorder.

29 Sep 2021

Insulin resistance linked to an increased risk of major depressive disorder

Stanford Medicine scientists have linked insulin resistance to an increased risk of developing major depressive disorder.

23 Sep 2021

Study finds sharp fall in amputations among people with type 1 diabetes

Amputation in type 1 diabetes is becoming relatively less common in Sweden. The rate has fallen by just over 40 percent over an approximately 20-year period, a University of Gothenburg study shows.

8 Sep 2021

First-of-its-kind bionic arm restores natural behaviors in patients with upper limb amputations

Cleveland Clinic researchers have engineered a first-of-its-kind bionic arm for patients with upper-limb amputations that allows wearers to think, behave and function like a person without an amputation, according to new findings published in Science Robotics.

1 Sep 2021