Amyotrophic Lateral Sclerosis News and Research

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Glutamate identified as predictor of disease progression in multiple sclerosis

UCSF researchers have identified a correlation between higher levels of glutamate, which occurs naturally in the brain as a byproduct of metabolism, and greater disease burden in multiple sclerosis patients.

29 Apr 2009

Scientists suggest a mechanism for how lithium works in bipolar treatment

Lithium has been established for more than 50 years as one of the most effective treatments for bipolar mood disorder.

22 Apr 2009

Stem cell therapy used to fight amyotrophic lateral sclerosis

A team of Utahns is collaborating on a stem cell therapy to fight amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease.

21 Apr 2009

Coffee, caffeine and amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages key neurons in the brain and spinal cord.

20 Apr 2009

Rochester scientist wins major award for Alzheimer's research

A Rochester researcher whose work has opened up a whole new avenue in Alzheimer's disease research has received a major prize from the American Academy of Neurology.

15 Apr 2009

Blood test predicts chance of frontal lobe dementia

Frontal lobe dementia (Frontotemporal Dementia, FTD) strikes people at an earlier age. After Alzheimer's disease, FTD is the form of dementia that occurs most frequently in patients younger than 65.

8 Mar 2009

Discovery of new gene associated with Lou Gehrig's disease

A collaborative research effort spanning nearly a decade between researchers at Massachusetts General Hospital (MGH), MIT, the Broad Institute, King's College London (KCL) and other institutions has identified a novel gene for inherited amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease).

5 Mar 2009

New treatment target for chronic abdominal pain

High levels of a protein linked to the way pain signals are sent to the brain led to a decrease in abdominal pain in a recent study in mice.

2 Mar 2009

Researchers isolate gene mutations in patients with inherited amyotrophic lateral sclerosis

Researchers at the University of Massachusetts Medical School (UMMS) have discovered a new gene whose mutations cause familial amyotrophic lateral sclerosis (ALS), a fatal neurological disorder.

26 Feb 2009

New gene associated with Lou Gehrig's disease

A collaborative research effort spanning nearly a decade between researchers at Massachusetts General Hospital (MGH) and King's College London (KCL) has identified a novel gene for inherited amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease).

26 Feb 2009

A second MND gene mutation in one year signifies rapid research progress

A collaborative research project involving Professor Christopher Shaw of the Institute of Psychiatry, King's College London (KCL), Dr Tom Kwiatkowski at Massachusetts General Hospital (MGH) and Professor Robert H Brown at University of Massachusetts, has revealed that mutations in a gene called FUS (fused in sarcoma) cause familial Motor Neuron Disease (also known as Amyotrophic Lateral Sclerosis).

26 Feb 2009

Scientists make electrically active motor neurons from iPS cells

Stem cells scientists at UCLA showed for the first time that human induced pluripotent stem (iPS) cells can be differentiated into electrically active motor neurons, a discovery that may aid in studying and treating neurological disorders.

25 Feb 2009

Researchers generate functional neurons from induced pluripotent stem (iPS) cells

In a new study, researchers were able to generate functionally mature motor neurons from induced pluripotent stem (iPS) cells, which are engineered from adult somatic cells and can differentiate into most other cell types.

24 Feb 2009

Significant Rett syndrome discovery

A paper published online today in Nature Neuroscience reveals the presence of methyl CpG binding protein 2 (MeCP2) in glia. MeCP2 is a protein associated with a variety of neurological disorders, including Rett Syndrome, the most physically disabling of the autism spectrum disorders.

23 Feb 2009

Human stem cells provide a new model for Lou Gehrig's disease

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a devastating condition in which motor neuron degeneration causes progressive loss of movement and muscle tone, leading to death.

23 Feb 2009

Neuralstem's ALS trial on hold

Neuralstem, Inc. has announced its spinal cord stem cell trial to treat Amyotrophic Lateral Sclerosis (ALS) is on clinical hold and that the Federal Drug Administration (FDA) has provided the Company with specific comments, questions and recommendations for modifications to its protocol.

22 Feb 2009