Angiotensin Converting Enzyme 2 News and Research

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Can human coronaviruses infect the GI tract?

Researchers review current findings on how human coronaviruses like SARS-CoV-2 might cause GI symptoms.

22 May 2022

Exploring the possibility of whether surface ACE2 carried by extracellular vesicles can facilitate SARS-CoV-2 infection

Researchers explored whether surface ACE2 carried by EVs can facilitate the entry of SARS-CoV-2 into host cells.

20 May 2022

Important methodology for targeting conserved epitopes of SARS-CoV-2 and an immune-focused approach in pan-sarbeco and universal CoV vaccine design

A new study has focused on designing immunogens associated with the conserved region of the spike protein of SARS-CoV-2.

20 May 2022

The link between androgens and COVID-19

A new paper examines the association between androgens and COVID-19, as revealed by the research carried out on this topic throughout the pandemic.

20 May 2022

Study explores if prior infection with SARS-CoV-2 increased sensitivity to a mitochondrial toxin known to induce parkinsonism

The authors of the current study looked at the potential for an increased risk of parkinsonism following a bout of SARS-CoV-2 infection through accepted post-viral mechanisms.

20 May 2022

Natural immunity weak and short-lived in unvaccinated after Omicron infection

In a recent study posted to the journal Nature, researchers showed that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron infection without SARS-CoV-2 vaccination conferred poor cross-variant neutralizing capacities.

20 May 2022

COVID-19's impact on sex and fertility

The potential effects of SARS-CoV-2 on sexual activity and fertility.

20 May 2022

SARS-CoV-2 zoonotic transmission prediction using ACE2 receptor variation is limited

In a recent study posted to the bioRxiv* preprint server, researchers at the University of Glasgow assessed the variation in angiotensin-converting enzyme 2 (ACE2) in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) host prediction.

19 May 2022

Researchers explore SARS-CoV-2 infection in lung myeloid cells

Scientists discuss how SARS-CoV-2 utilizes myeloid cells to allow for the subsequent viral colonization in the lungs.

19 May 2022

Scientists investigate relevance of COVID-19 vaccine-mediated T cell immunity to SARS-CoV-2 variants

Researchers showed the significance of T cell-based immunity against the SARS-CoV-2 variants exhibiting evasion to antibody-centric immunity.

19 May 2022

The detection and isolation of bat sarbecoviruses from several locations in Japan

The current paper reports the detection of bat Sarbecoviruses from multiple places in Japan with their characteristics.

19 May 2022

In-depth characterization of the BA.2 versus BA.1 variant

In a recent study published in the journal Nature, researchers evaluated the pathogenicity and infectivity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.2 variant in hamsters and mice.

19 May 2022

Evaluating efficacy of SARS-CoV-2 antivirals in a mouse model

In a recent study posted to the bioRxiv* pre-print server, researchers from Belgium evaluated the efficacy of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antiviral drugs in a severe combined immunodeficient (SCID) mouse model.

18 May 2022

Recombinant protein vaccine stands up to SARS-CoV-2 variants

A study by researchers in Texas describes a mouse model in which a subunit vaccine with alum-CpG adjuvant was tested for its ability to induce a broadly neutralizing antibody response against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

18 May 2022

Only some coronaviruses found to have pandemic-causing potential

In a new study, scientists focused on resolving the mystery of why some coronaviruses have the potential of causing a pandemic while others do not.

18 May 2022

Gestational diabetes mellitus in overweight and obese pregnant women may increase COVID-19 severity

Researchers reported that gestational diabetes mellitus and obesity were associated with severe COVID-19.

18 May 2022

Discovery of a potent SARS-CoV-2 RBD specific human monoclonal antibody

A recent article posted to the bioRxiv* preprint server demonstrated structural underpinnings of the neutralization of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variants by 002-S21F2, an extensive SARS-CoV-2 neutralizing antibody.

18 May 2022

Compound found in Datura shows promise as antiviral agent against SARS-CoV-2

Researchers from Naval Medical University have been investigating anisodamine, used in traditional Chinese medicine, to inhibit SARS-CoV-2 infection in cellular models. The study is published in the journal Biochemical and Biophysical Research Communications.

17 May 2022

Exploring mutational energetics and the role of arginine blockers in COVID-19 treatments

A new study aimed to describe the roles of certain specific mutations in SARS-CoV-2 strains, with respect to their ability to conformationally stabilize S-protein structure resulting in enhanced receptor-binding domain ACE2 binding.

17 May 2022

Researchers develop treatment that suppresses mutational escape of SARS-CoV-2

Researchers from Xiamen University have created a new treatment that is less likely to be affected by mutations in the receptor-binding domain of SARS-CoV-2.

17 May 2022

Angiotensin Converting Enzyme 2 News and Research

Can human coronaviruses infect the GI tract?

Exploring the possibility of whether surface ACE2 carried by extracellular vesicles can facilitate SARS-CoV-2 infection

Important methodology for targeting conserved epitopes of SARS-CoV-2 and an immune-focused approach in pan-sarbeco and universal CoV vaccine design

The link between androgens and COVID-19

Study explores if prior infection with SARS-CoV-2 increased sensitivity to a mitochondrial toxin known to induce parkinsonism

Natural immunity weak and short-lived in unvaccinated after Omicron infection

COVID-19's impact on sex and fertility

SARS-CoV-2 zoonotic transmission prediction using ACE2 receptor variation is limited

Researchers explore SARS-CoV-2 infection in lung myeloid cells

Scientists investigate relevance of COVID-19 vaccine-mediated T cell immunity to SARS-CoV-2 variants

The detection and isolation of bat sarbecoviruses from several locations in Japan

In-depth characterization of the BA.2 versus BA.1 variant

Evaluating efficacy of SARS-CoV-2 antivirals in a mouse model

Recombinant protein vaccine stands up to SARS-CoV-2 variants

Only some coronaviruses found to have pandemic-causing potential

Gestational diabetes mellitus in overweight and obese pregnant women may increase COVID-19 severity

Discovery of a potent SARS-CoV-2 RBD specific human monoclonal antibody

Compound found in Datura shows promise as antiviral agent against SARS-CoV-2

Exploring mutational energetics and the role of arginine blockers in COVID-19 treatments

Researchers develop treatment that suppresses mutational escape of SARS-CoV-2

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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