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New non-invasive treatment for patients suffering from treatment-resistant depression and dementia

A joint research team from the LKS Faculty of Medicine, The University of Hong Kong (HKUMed) and City University of Hong Kong (CityU) has discovered that the electrical stimulation of the eye surface can alleviate depression-like symptoms and improve cognitive function in animal models.

8 Jul 2022

Nanoparticle vaccine could protect against animal viruses including future SARS-CoV-2 variants

A recent study published in the Science journal depicted that mosaic receptor-binding domain (RBD) nanoparticles immunize from diverse sarbecovirus challenges, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), among animal models.

8 Jul 2022

Novel COVID-19 antibody delivery approach advances to clinical trials

Under a Defense Advanced Research Projects Agency (DARPA) and Joint Program Executive Office for Chemical, Biological, Radiological and Nuclear Defense (JPEO-CBRND) funded program, a novel COVID-19 antibody delivery approach has advanced to clinical trials.

7 Jul 2022

Study: Lactobacilli living in female urinary tract's microbiome can kill nearby pathogenic bacteria

Lactobacilli that live in the human female urinary tract's microbiome are competitive and kill nearby pathogenic bacteria, according to the first study of its kind by a team led by microbiologist Dr. Tanya Sysoeva of The University of Alabama in Huntsville.

6 Jul 2022

Genetically engineered kidney organoids solve mystery of a rare disease

Researchers have solved a medical mystery in a poorly understood disease by uncovering which cells cause tumors in patients with tuberous sclerosis complex (TSC).

6 Jul 2022

Gene defect underlying Krabbe disease causes degeneration of neurons directly, study finds

The gene defect underlying Krabbe disease causes degeneration of neurons directly, independent of its effects on other cell types, according to a new study publishing July 5th in the open-access journal PLOS Biology by Daesung Shin of the University at Buffalo, U.S. and colleagues.

5 Jul 2022

Scientists discover how a protein and enzymes interact to allow hepatitis A virus replication

The viral replication cycle is crucial for a virus to spread inside the body and cause disease. Focusing on that cycle in the hepatitis A virus (HAV), UNC School of Medicine scientists discovered that replication requires specific interactions between the human protein ZCCHC14 and a group of enzymes called TENT4 poly(A) polymerases.

4 Jul 2022

Comprehensive atlas of genetic data on zebrafish will benefit medical and life science researchers

Medical and life science researchers will benefit from the most comprehensive atlas yet of genetic data on zebrafish, newly published research suggests.

4 Jul 2022

Combining AI and Zebrafish to Accelerate Drug Discovery

As part of our SLAS Europe 2022 coverage, we speak to Dr. Javier Terriente, Co-founder and Chief of Drug Development at ZeClinics, about how zebrafish could be the future for discovering new therapeutics.

From Society for Laboratory Automation and Screening (SLAS) 1 Jul 2022

Antiretroviral drug used to treat HIV ameliorates cognitive deficits in mouse model of Down syndrome

Lamivudine, a commonly-used antiretroviral drug for treating HIV, improves cognition in a mouse model of Down syndrome, according to the findings of a joint new study by researchers at the Centre for Genomic Regulation (CRG) and the IrsiCaixa AIDS Research Institute, a center jointly promoted by the "la Caixa" Foundation and the Department of Health of the Generalitat de Catalunya.

28 Jun 2022

COVID-19 can cause metabolism problems by interfering with insulin signaling, study reveals

It has become abundantly clear that coronavirus disease 19 (COVID-19), despite being transmitted by breathing in the SARS-CoV-2 virus, can have harmful effects far beyond the lungs.

27 Jun 2022

Listeria-based booster vaccine strategy offers improved protection against recurrent colorectal cancer

Colorectal, pancreatic, esophageal and stomach cancers-;some of the deadliest kinds of cancer-; have high recurrence rates where the cancer comes back even after successful surgery or radiation treatment.

23 Jun 2022

Researchers identify the role of TREM2-positive macrophages in non-alcoholic fatty liver disease

A MedUni Vienna study team has identified the role of a specific subtype of macrophages (white blood cells) in progressive non-alcoholic fatty liver disease.

21 Jun 2022

New protocol can develop safe, efficient pluripotent stem cell-based therapies for macular degeneration

As we age, so do our eyes; most commonly, this involves changes to our vision and new glasses, but there are more severe forms of age-related eye problems.

14 Jun 2022

Probiotic bacteria may enhance anti-cancer activities of tamoxifen to reduce ER+ breast cancer risk

Probiotic bacteria may enhance anti-cancer activities of the breast cancer drug tamoxifen and other endocrine-targeted therapies, which could help reduce the risk of estrogen receptive positive (ER+) breast cancer, suggests a new study presented Monday at ENDO 2022, the Endocrine Society's annual meeting in Atlanta, Ga.

13 Jun 2022

Age exacerbates COVID neuroimmunological symptoms

In a recent study posted to the bioRxiv* pre-print server, researchers at the University of Illinois at Chicago investigated whether aging exacerbated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection-induced neuropsychiatric disorders.

6 Jun 2022

Animal Model News and Research

New non-invasive treatment for patients suffering from treatment-resistant depression and dementia

Nanoparticle vaccine could protect against animal viruses including future SARS-CoV-2 variants

Novel COVID-19 antibody delivery approach advances to clinical trials

Study: Lactobacilli living in female urinary tract's microbiome can kill nearby pathogenic bacteria

Genetically engineered kidney organoids solve mystery of a rare disease

Gene defect underlying Krabbe disease causes degeneration of neurons directly, study finds

Scientists discover how a protein and enzymes interact to allow hepatitis A virus replication

Comprehensive atlas of genetic data on zebrafish will benefit medical and life science researchers

Combining AI and Zebrafish to Accelerate Drug Discovery

Antiretroviral drug used to treat HIV ameliorates cognitive deficits in mouse model of Down syndrome

COVID-19 can cause metabolism problems by interfering with insulin signaling, study reveals

Listeria-based booster vaccine strategy offers improved protection against recurrent colorectal cancer

Researchers identify the role of TREM2-positive macrophages in non-alcoholic fatty liver disease

New protocol can develop safe, efficient pluripotent stem cell-based therapies for macular degeneration

Probiotic bacteria may enhance anti-cancer activities of tamoxifen to reduce ER+ breast cancer risk

Age exacerbates COVID neuroimmunological symptoms

New method to combat malaria turns the disease against itself

Research provides new insight into how Crimean-Congo hemorrhagic fever virus causes disease

Pioneering study could transform the treatment landscape for babies with infantile spasms

Evaluating efficacy of SARS-CoV-2 antivirals in a mouse model

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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