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Novavax's pandemic flu vaccines show promise

Novavax, Inc.'s novel virus-like particle (VLP) vaccines have been shown to be effective in generating protection against pandemic influenza as well as cross protection against different strains of the virus in pre-clinical studies, according to data presented at the Phacilitate Vaccine Forum.

22 Jan 2007

Modified skin cells that may help protect cultured skin substitutes from infection

Cincinnati burn researchers have created genetically modified skin cells that, when added to cultured skin substitutes, may help fight off potentially lethal infections in patients with severe burns.

9 Jan 2007

Inhibiting a particular cancer-causing gene improves radiation effectiveness

Inhibiting a particular cancer-causing gene can enhance the cell-killing effects of radiation, a team of radiation oncologists and cancer biologists at the Kimmel Cancer Center at Thomas Jefferson University in Philadelphia has found.

8 Nov 2006

Potential for first diagnostic DNA test to guide antidepressant treatment

Treatment of depression is difficult for both patients and for psychiatrists. While there are numerous drugs available that work, finding the right one -- or right combination -- is, at times, a matter of trial and error.

31 Oct 2006

Insulin receptor stops progression of Alzheimer's disease

Stimulation of a receptor in the brain that controls insulin responses has been shown to halt or diminish the neurodegeneration of Alzheimer's disease, providing evidence that the disease can be treated in its early stages, according to a study by researchers at Rhode Island Hospital and Brown Medical School.

21 Sep 2006

Reactive oxygen species in cancer cells

A biochemical alteration that has long been viewed as an adverse aspect of tumor biology may turn out to be a deadly double-edged sword for the cancer cells themselves.

12 Sep 2006

Discovery of a new gene that stimulates the growth of natural bypasses

World Congress of Cardiology Report - Researchers from the Max-Planck-Institute for Heart and Lung Research (MPI) in Bad Nauheim, Germany, have identified a gene, whose therapeutic use may be beneficial for patients suffering from obstructive arterial diseases.

5 Sep 2006

The heart can heal itself

World Congress of Cardiology Report - Despite the dramatic advances in the care of patients with cardiovascular diseases that have occurred in the second half of the 20th century, heart failure (HF) is the most common cause of death in developed nations.

5 Sep 2006

Mature muscle fibers can revert to become cancerous

Mature muscle fibers, rather than their less-developed neighbors, are the tissues that turn malignant in a soft-tissue cancer that strikes children and teens, researchers at UT Southwestern Medical Center and Children's Medical Center Dallas have found.

4 Sep 2006

The endocannabinoid system controls key epileptogenic circuits in the hippocampus

The same brain machinery that responds to the active substance in marijuana provides a central "on-demand" protection against seizures, researchers have found. They said their discoveries suggest that the "endocannabinoid" system might constitute a prime target for drugs against seizures of epilepsy and other neurodegenerative diseases.

16 Aug 2006

Altering fatty acid levels in diet may reduce prostate cancer growth rate

UCLA researchers found that altering the fatty acid ratio found in the typical Western diet to include more omega-3 fatty acids and decrease the amount of omega-6 fatty acids may reduce prostate cancer tumor growth rates and PSA levels.

2 Aug 2006

Birch bark compound may be potent prostate cancer fighter

A compound found in the bark of the white birch tree - betulonic acid, a derivative of betulinol - may finally have been rendered a water-soluble, bio-available drug, and is already showing the potential to be a possible agent against prostate cancer - in cell culture and in an animal model.

25 Jul 2006