Anosmia News and Research

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Stem cells with 'dual identity' associated with loss of smell from inflammation in chronic sinusitis

In experiments with mice and human tissue samples, Johns Hopkins Medicine researchers report evidence that neuronal stem cells in the part of the nose responsible for the sense of smell transform themselves to perpetuate the long-term inflammation in chronic sinusitis.

19 Sep 2019

Electrical impulses to the olfactory bulb can provide sense of smell, research shows

Physicians at Massachusetts Eye and Ear have, for the first time, induced a sense of smell in humans by using electrodes in the nose to stimulate nerves in the olfactory bulb, a structure in the brain where smell information from the nose is processed and sent to deeper regions of brain.

27 Nov 2018

Monell Center and Jefferson sign Agreement of Cooperation to improve human health

The Monell Center and Jefferson (Philadelphia University and Thomas Jefferson University) announced today the signing of an Agreement of Cooperation, outlining how the two institutions will collaborate over the next year to develop joint scientific programs and clinical opportunities to advance their shared mission of improving human health.

30 Aug 2018

New conference to establish roadmap for treatment-focused research on smell and taste disorders

The Monell Center, in partnership with the University of Florida Center for Smell and Taste and the Rocky Mountain Taste and Smell Center at the University of Colorado School of Medicine, will host an interdisciplinary two-day conference in November 2018 to establish a roadmap for treatment-focused research on smell and taste disorders.

27 Jun 2018

Researchers discover mutations in a gene related to obesity

Researchers have discovered mutations in a gene related to obesity, offering new treatment possibilities in the fight against the global epidemic.

8 Jan 2018

Scientists use new RNA sequencing and statistical techniques to track stem cells in the nose

Adult stem cells have the ability to transform into many types of cells, but tracing the path individual stem cells follow as they mature and identifying the molecules that trigger these fateful decisions are difficult in a living animal.

12 May 2017

Sodium citrate nasal spray could offer temporary improvement in ability to smell

A substance commonly used to treat bladder issues could temporarily treat people who have lost their sense of smell, according to research published in the journal Clinical Otolaryngology.

5 Apr 2017

Monell Center to promote Anosmia Awareness Day with new educational outreach initiatives

The Monell Center announces three new educational outreach initiatives to promote Anosmia Awareness Day, which takes place on February 27. Each was designed to increase awareness and increase the limited information currently available about anosmia, the loss of our sense of smell, which affects over six million Americans and many millions more worldwide.

25 Feb 2015

Monell Center receives NIH grant to develop clinical tool that can predict anosmia

Monell Center scientist Kai Zhao, PhD, is principal investigator on a $1.5M 4-year grant from the National Institute on Deafness and Other Communication Disorders, part of the National Institutes of Health, to further develop clinical methodology that can predict the path of air flow through a person's nasal passages.

23 Jan 2015

Monell Center announces advocacy program to identify biological causes of smell loss

On Anosmia Awareness Day, the Monell Center announces "A Sense of Hope: The Monell Anosmia Project," a three-year $1.5M fundraising campaign to support a research and advocacy program focused on anosmia, the loss of the sense of smell.

4 Mar 2014

Better ways to combat mosquitoes

In an advance toward providing mosquito-plagued people, pets and livestock with an invisibility cloak against these blood-sucking insects, scientists today described discovery of substances that occur naturally on human skin and block mosquitoes’ ability to smell and target their victims.

11 Sep 2013

Mutations in Ggamma13 gene may contribute to certain forms of smell disorders in humans

Researchers at the Monell Center and collaborators have identified a protein that is critical to the ability of mammals to smell. Mice engineered to be lacking the Ggamma13 protein in their olfactory receptors were functionally anosmic - unable to smell.

7 May 2013

Study: Neural-crest stem cells also play a key role in building olfactory sensory neurons

When our noses pick up a scent, whether the aroma of a sweet rose or the sweat of a stranger at the gym, two types of sensory neurons are at work in sensing that odor or pheromone.

26 Mar 2013

Gene therapy approach restores ability to smell in mouse model of congenital anosmia

Scientists funded by the National Institutes of Health have restored the ability to smell in a mouse model of a human genetic disorder that causes congenital anosmia-the inability to smell from birth. The approach uses gene therapy to regrow cilia, cell structures that are essential for olfactory function.

3 Sep 2012

Scientists restore sense of smell in mice through gene therapy

Scientists have restored the sense of smell in mice through gene therapy for the first time -- a hopeful sign for people who can't smell anything from birth or lose it due to disease.

3 Sep 2012

Potential PD biomarkers identified for sleep behavior disorder

Concomitant olfaction abnormality and increased substantia nigra echogenicity may be preclinical manifestations of parkinsonism in patients with idiopathic rapid eye movement sleep behavior disorder, research suggests.

3 Aug 2012

23andMe identifies seven SNPs associated with breast size

Using data from its unique online research platform, 23andMe, a leading personal genetics company, has identified seven single-nucleotide polymorphisms (SNPs) significantly associated with breast size, including three SNPs also correlated with breast cancer in a genome-wide association study (GWAS) now published online in BMC Medical Genetics.

4 Jul 2012

Six novel genetic associations for early onset male pattern baldness

Using data from its unique online research platform, 23andMe, a leading personal genetics company, has contributed to the finding of six novel genetic associations for early onset male pattern baldness (androgenetic alopecia) in a genome-wide association study now published online in the journal PLoS Genetics.

20 Jun 2012

Colonic tissue may help predict Parkinson's disease

Two studies by neurological researchers at Rush University Medical Center suggest that, in the future, colonic tissue obtained during either colonoscopy or flexible sigmoidoscopy may be used to predict who will develop Parkinson's disease, a neurodegenerative disorder of aging that that leads to progressive deterioration of motor function due to loss of neurons in the brain that produce dopamine, a neurotransmitter essential to executing movement.

16 May 2012

Five significant genetic associations for hypothyroidism found

Using its unique online research platform, 23andMe, a leading personal genetics company, has found five significant genetic associations for hypothyroidism in the largest known genome-wide association study of hypothyroidism conducted to date. The details of the study are now available online in the journal PLoS ONE.

9 Apr 2012