Antibodies News and Research

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Early neutralizing response to SARS-CoV-2 dominated by IgA antibodies

Researchers from France and the U.S. demonstrated how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection could induce an early and vigorous virus-specific IgA response that paves the way for the production of SARS-CoV-2 IgG antibodies, with even better neutralizing properties. Their paper is currently available on the medRxiv preprint server.

14 Jun 2020

NIAID and Moderna scientists describe SARS-CoV-2 vaccine development

Researchers at the National Institute of Allergy and Infectious Diseases and Moderna Inc., have described the potent neutralizing effects of a candidate vaccine for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that is currently being tested in a phase II trial.

14 Jun 2020

JRC creates a database of COVID-19 diagnostic devices and test methods

As part of EU efforts to provide guidance on the use of coronavirus tests, the JRC has created a database of COVID-19 in vitro diagnostic devices and test methods that gathers information on available tests in one place.

12 Jun 2020

Study: Only a minority of Geneva population has been infected by Covid-19 pandemic

A study carried out among 2'766 people by the University Hospitals of Geneva (HUG), the Geneva Centre for Emerging Viral Diseases, and the University of Geneva (UNIGE), Switzerland, reveals that, at the time of the decline of the Coronavirus pandemic, only 10.8% of the Geneva population had been infected with Covid-19.

12 Jun 2020

Study initiates hydroxychloroquine clinical trial to prevent COVID-19 in healthy people

Rush University Medical Center has opened enrollment for a new clinical trial investigating whether the drug hydroxychloroquine is better than a placebo in preventing COVID-19 infection in healthy people working in health care settings.

12 Jun 2020

New, reliable tests identified for detecting antibodies specific to SARS-CoV-2

A new analysis of blood sera taken from 63 COVID-19 patients, 71 controls, and various coronavirus-exposed animals provides strong support for the use of the SARS-CoV-2 virus' receptor-binding domain (RBD) as an antigen for reliable tests to detect antibodies to the virus.

12 Jun 2020

UNC scientists develop new kind of antibody test for COVID-19

As the COVID-19 pandemic continues with many thousands of new infections reported each day, there is a need for widely applicable surveillance testing to gain a better understanding of infection rates, especially the number of infections in people with mild or no symptoms, who can still be carriers.

11 Jun 2020

WVU researchers develop new diagnostic and antibody tests for COVID-19

COVID-19 tests are in short supply. The companies that make the necessary chemicals--called reagents--can't keep up with demand. But researchers at West Virginia University are developing new tests on their own to identify who has COVID-19 now and who had it in the past but recovered.

11 Jun 2020

Synthetic nanobodies potent neutralizers for SARS-CoV-2

Researchers at the Chinese Academy of Sciences report the generation of potent synthetic nanobodies that selectively and efficiently neutralize severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pseudovirus.

11 Jun 2020

Progression and severity of COVID-19 highly dependant on cytokine changes

A new review paper by the researchers from Spain, published in the journal Cytokine & Growth Factor Reviews, demonstrates how changes in the levels of cytokines and other biomolecules are associated with the presence and more serious prognosis of coronavirus disease (COVID-19).

11 Jun 2020

Study reveals novel mechanism that triggers a cell-mediated immune response

Viruses and other disease-causing microbes influence the type of immune response their hosts will develop against them. In some cases, the predominant response involves antibodies, proteins made by the immune system that specifically recognize parts of the invading microbe and mediate its destruction.

11 Jun 2020

Scientists develop new test to help identify people at risk for developing liver cancer

Scientists have developed a new test that can help identify people who are likely to develop hepatocellular carcinoma (HCC), the most common form of liver cancer. The approach uses a simple blood test to check for the patient's previous exposure to certain viruses.

11 Jun 2020

New sensor could dramatically improve the efficiency of Covid-19 tests

A new sensor that can give an immediate response to the presence of coronavirus could dramatically improve the efficiency of testing and overcome some of the current surveillance bottlenecks, believe its Swedish developers.

11 Jun 2020

Turning autoimmunity drugs into anti-cancer treatments

Professor Mark Cragg speaks to News-Medical about his research which involves turning autoimmunity drugs into anti-cancer treatments.

11 Jun 2020

Hydroxychloroquine suppresses 'trained immunity'

A new study published on the preprint server medRxiv in June 2020 shows that the drug hydroxychloroquine (HCQ) suppresses a form of immunity called ‘trained immunity,’ with repercussions for its potential use to treat COVID-19.

11 Jun 2020

Determining the reliability of COVID-19 antibody tests

With stay-at-home orders expiring around the world, many hope that COVID-19 antibody testing will help businesses and institutions reopen safely.

11 Jun 2020

Maternal SARS-CoV-2 infection not harmful in first trimester pregnancies

A new Danish study published on the preprint server medRxiv in June 2020 shows that infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in early pregnancy does not carry an increased risk of fetal harm.

10 Jun 2020

Females mount stronger T-cell response to SARS-CoV-2

A new study published on the preprint server medRxiv in June 2020 shows that immune cells, antibody levels, cytokine levels, and viral loads contribute to the sex difference seen in response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

10 Jun 2020

Scientists investigate immune responses to SARS-CoV-2 spike immunogens

The coronavirus pandemic is actively spreading across the globe, with millions of people infected. Amid the global health crisis, scientists race to develop an effective vaccine against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

10 Jun 2020

Anticardiolipin antibodies and COVID-19

A new study has shown that anticardiolipin antibodies are associated with the novel coronavirus infection or severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes COVID-19.

10 Jun 2020