Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

Targeted cancer therapies: Another step forward

While it is clear that the treatment of cancer has already begun to undergo a paradigm shift with the inclusion of innovative targeted therapies into current regimens, it would be wrong to assume these products will entirely replace traditional chemotherapy as the standard treatment for cancer sufferers.

22 Dec 2005

Children could be saved from neuroblastoma using antibody therapy

Combination of T cell, antibody to neuroblastoma cells and molecule that spurs T cell growth is designed to treat low initial tumor levels or small cancer cell populations that survive initial treatment, according to St. Jude.

22 Dec 2005

Japanese brewery claims antibody works against bird flu

A Japanese brewery says its U.S. subsidiary has developed an antibody that may be effective against bird flu.

19 Dec 2005

Good results with cervical cancer vaccine in young girls

Drug company GlaxoSmithKline have had a good result with their new vaccine which was designed to prevent infection with the virus that causes cervical cancer.

19 Dec 2005

Aromatase inhibitors may slow growth of lung cancer

A few years ago researchers discovered that, much like breast tumors, some lung tumors also thrive on estrogen. Now a medical student conducting research on a Howard Hughes Medical Institute (HHMI) fellowship and colleagues have managed to stop the growth of human lung cancer cells in mice with a class of breast cancer drugs called aromatase inhibitors.

15 Dec 2005

New cell findings have implications for cancer, immune disorders

It all started 5 years ago when a University of Calgary neuroscientist sent blood from a patient with a neurological disorder to the laboratory of Dr. Marvin Fritzler, professor of medicine / biochemistry & molecular biology at the University of Calgary Faculty of Medicine.

15 Dec 2005

MorphoSys signs agreement with Merck

MorphoSys AG announced today that it has signed a five-year license agreement with U.S. pharmaceutical company Merck & Co., Inc. for the use of MorphoSys’s HuCAL GOLD and AutoCAL technologies in research and development of human therapeutic antibodies.

14 Dec 2005

A colonization factor links Vibrio cholerae environmental survival and human infection

Opening a new door to an effective vaccine and therapy for a disease that strikes thousands annually, researchers at Dartmouth Medical School discovered that the bacteria that causes the intestinal disease Cholera spreads in the environment in much the same way it infects humans.

13 Dec 2005

Anti-Abeta42 and Anti-Abeta40–specific monoclonal antibodies attenuate amyloid deposition in an Alzheimer disease mouse model

Current hypotheses suggest that it is the accumulation over time of amyloid beta peptide 1–42 (Abeta42) that triggers changes in the brain that lead to cognitive dysfunction in Alzheimer's disease.

13 Dec 2005

SPARC promotes heart muscle formation from stem cells

The protein SPARC plays a key role in the development of heart muscle in the embryo. An Austrian Science Fund FWF project has discovered this previously unknown role of SPARC.

12 Dec 2005

Generation of neoantigenic epitopes after posttranslational modification of Type II collagen by factors present within the inflamed joint

Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation of the joints, which gradually erodes the cartilage and bone.

7 Dec 2005

New study sheds light on role of type II collagen in rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease which gradually erodes cartilage and bone and is characterised by chronic inflammation of the joints.

6 Dec 2005

Intervention in immune regulation can prevent onset of type-1 diabetes

Some forms of diabetes could feasibly be prevented. Scientists at the German Research Centre for Biotechnology (GBF) in Braunschweig recently were able to do just that in experiments with mice.

6 Dec 2005

Herceptin - can healthcare afford this expensive drug?

New research into the cost of using the breast cancer drug Herceptin warns that healthcare authorities and the organisations advising them should not rush to prescribe it for early breast cancer without working out extremely carefully the budget implications and cost-effectiveness of the drug.

2 Dec 2005

New anthrax antibody

A new anthrax antibody engineered by scientists at The University of Texas at Austin protects and defends against inhalation anthrax without the use of antibiotics and other more expensive antibodies.

2 Dec 2005

Contact with pigs increases risk of animal flu viruses

Farmers, veterinarians and meat processors who routinely come into contact with pigs in their jobs have a markedly increased risk of infection with flu viruses that infect pigs, according to a study funded in part by the National Institute of Allergy and Infectious Diseases (NIAID).

28 Nov 2005