Antidepressant News and Research

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Antidepressants are medicines that treat depression. Your doctor can prescribe them for you. They can improve your mood, sleep, appetite and concentration. It may take several weeks for them to help. There are several types of antidepressants. You and your doctor may have to try several before finding what works best for you.

Pregnancy and birthing have long-lasting effects on the maternal brain

Pregnancy and birthing have profound, often long-lasting, effects on brain physiology, mood and behavior. New findings on the neurobiology of the maternal experience were presented at Neuroscience 2022, the annual meeting of the Society for Neuroscience and the world's largest source of emerging news about brain science and health.

9 Nov 2022

Psilocybin could be a promising therapeutic strategy for people with treatment-resistant depression

Researchers at Trinity College Dublin have participated in the largest and most rigorous clinical trial to date of psilocybin (a psychoactive ingredient in magic mushrooms), pointing to the possibility that COMP360 psilocybin with psychological support could be a beneficial therapeutic strategy for people with treatment-resistant depression (TRD).

7 Nov 2022

Distinct brain networks may be potential targets for neuromodulation therapies to treat depression

A new study that links the location of brain injury to levels of depression in patients following the injury has identified two distinct brain networks; one associated with increased depression symptoms and one associated with decreased depression symptoms.

13 Oct 2022

Are men or women impacted more by adverse reactions to prescription drug treatments?

Recently, researchers presented an overview of sex-based differences in adverse drug reactions (ADRs) based on epidemiology, technique, and underlying mechanism data.

11 Oct 2022

Researchers to study how pregnant women with depression respond to antidepressants

Using a combination of biomarkers and mood assessments, researchers will study how pregnant women who are experiencing depression respond to different antidepressants in a clinical trial funded by a grant from the National Institutes of Health to UTHealth Houston.

5 Oct 2022

New compound triggers the same anti-depressant action as rapidly acting psychedelic drugs

While illegal for recreational use, psychedelic drugs are showing great promise as treatments for severe depression and anxiety, as well as alcohol addiction and other conditions.

28 Sep 2022

Combination of three existing drugs extends survival in mouse models of lethal brain cancer

A Ludwig Cancer Research study has identified a combination of three existing drugs that significantly extends survival in mouse models of the lethal brain cancer glioblastoma multiforme (GBM).

20 Sep 2022

Nutritional approaches targeting gut microbiome could improve brain disorders

A new review published in the Clinical Nutrition and Metabolic Care journal focused on studies that utilized the dietary gut microbiota–target interventions to improve mental health conditions. It also discussed some suggestions for developing more robust and informative interventions for diet–microbiome studies.

15 Sep 2022

Magnus’ SAINT Neuromodulation System receives 510(k) clearance from FDA for treatment of major depressive disorder

Magnus Medical, Inc., a medical device company and developer of brain stimulation technology for treatment of neuropsychiatric disorders, today announced it received 510(k) clearance from the U.S. Food & Drug Administration for the SAINTTM Neuromodulation System for the treatment of major depressive disorder (MDD) in adults who have failed to achieve satisfactory improvement from prior antidepressant medications in the current episode.

6 Sep 2022

FAU and Tel Aviv researchers receive grant to tackle Alzheimer’s-related mood disorders

Alzheimer's disease (AD) is the most common type of dementia affecting an estimated 6.3 million Americans age 65 and older. Without the development of medical breakthroughs to prevent, treat, slow or cure AD that number could grow to 13.8 million by 2060.

29 Aug 2022

The risk of adverse reactions when herbal medications are taken with cancer drugs

A new study discusses phytovigilance initiatives based on the real-world use of herbal drugs in cancer along with conventional chemotherapy.

24 Aug 2022

Acid ceramidase is a SARS-CoV-2 host factor, study says

Fluoxetine, a common antidepressant, inhibits the SARS-CoV-2 coronavirus in cell cultures and in preparations from human lung tissue. This was demonstrated by researchers at Julius-Maximilians-Universität (JMU) Würzburg in the summer of 2020. However, the mechanism of this inhibition was utterly unclear, so the teams continued their research.

17 Aug 2022

Study identifies an optimal rTMS treatment regimen for older adults

A new study published in Frontiers in Aging Neuroscience is the first to identify an optimal Repetitive Transcranial Magnetic Stimulation (rTMS) treatment regimen for older adults with treatment-resistant depression, according to researchers at Hinda and Arthur Marcus Institute for Aging Research and the Deanna and Sidney Wolk Center for Memory Health at Hebrew SeniorLife.

16 Aug 2022

Integrated behavioral intervention effective at reducing depression and anxiety in obese adults

Results from a pilot clinical trial show that among a racially and ethnically diverse cohort of adults who were obese and depressed, an integrated behavioral intervention was more effective than usual care at reducing depression and associated anxiety symptoms than it was at promoting weight loss.

2 Aug 2022

Repurposing an antipsychotic drug to treat various types of cancer

To treat some of the psychosis issues associated with Parkinson's disease, physicians often prescribe pimavanserin, an antipsychotic drug that acts within the brain to prevent hallucinations and delusions.

28 Jul 2022

$50 million PCORI funding approved for studies focused on treating suicidal depression and bipolar depression

Research teams at Mass General Brigham's founding members, Brigham and Women's Hospital and Massachusetts General Hospital, have been approved for more than $50 million in funding awards by the Patient-Centered Outcomes Research Institute for studies focused on treating two important mental health conditions.

26 Jul 2022

Review: No clear evidence that serotonin levels are responsible for depression

After decades of study, there remains no clear evidence that serotonin levels or serotonin activity are responsible for depression, according to a major review of prior research led by UCL scientists.

20 Jul 2022

Study finds the cause behind women experiencing higher rates of depression than men

Although treatments for depression exist, sometimes these treatments don't work for many who use them. Furthermore, women experience higher rates of depression than men, yet the cause for this difference is unknown, making their illnesses, at times, more complicated to treat.

14 Jul 2022

New non-invasive treatment for patients suffering from treatment-resistant depression and dementia

A joint research team from the LKS Faculty of Medicine, The University of Hong Kong (HKUMed) and City University of Hong Kong (CityU) has discovered that the electrical stimulation of the eye surface can alleviate depression-like symptoms and improve cognitive function in animal models.

8 Jul 2022

Gun safety ‘wrapped in a mental health bill’: A look at health provisions in the new law

The gun safety law forged through tense bipartisan talks in the Senate last month has been heralded as the first federal legislation in 30 years to combat rising gun violence. But what often falls below the radar is the new law's focus on improving mental health services.

7 Jul 2022