Antidepressant News and Research

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Antidepressants are medicines that treat depression. Your doctor can prescribe them for you. They can improve your mood, sleep, appetite and concentration. It may take several weeks for them to help. There are several types of antidepressants. You and your doctor may have to try several before finding what works best for you.

Brain-stimulation therapy at home reduces major depression symptoms

This study highlights the efficacy of home-based tDCS in treating major depressive disorder, with significant improvements in depressive symptoms and remission.

22 Oct 2024

Scientists discover gut microbiome differences in children with autism

Researchers found differences in gut bacteria between children with autism and typically developing children but caution that more research is needed to clarify these associations and their therapeutic potential.

20 Oct 2024

Innovative approach by Waymark enhances health outcomes for Medicaid patients

Waymark, a public benefit company dedicated to improving access and quality of care in Medicaid, today published a peer-reviewed study in the New England Journal of Medicine (NEJM) Catalyst evaluating the impact of its early intervention model in its first year of service.

18 Oct 2024

Rising concerns over benzodiazepine prescriptions in older stroke survivors

Although there has been a slight downward trend in the prescription of benzodiazepines (depressants that relieve anxiety, muscle spasms, produce sedation and reduce seizures) among older adults over the last decade, the rate of first-time prescriptions for these medications after an ischemic (clot-caused) stroke is still sizable, according to research published today in Stroke, the peer-reviewed scientific journal of the American Stroke Association, a division of the American Heart Association.

17 Oct 2024

Safe storage crucial to prevent child drug poisoning

New data shows that the number of children suffering a seizure after swallowing medications or illegal substances has doubled between 2009 and 2023 in the US. The findings were presented today (Wednesday) at the European Emergency Medicine Congress.

16 Oct 2024

Liver X receptor beta offers new hope in treating depression and anxiety

Liver X receptor beta (LXRβ) shows potential in reducing depression and anxiety by improving neurogenesis, reducing neuroinflammation, and enhancing cognitive and emotional function. More research on LXR agonists could reveal new treatments for mental health disorders.

8 Oct 2024

Study reveals sponsorship bias in psychiatric drug trials

Psychiatric drugs are reported to be about 50% more effective in clinical trials funded by the drug's manufacturer than when trials of the same drug are sponsored by other groups, new research shows.

7 Oct 2024

Cardiovascular risks post-COVID-19 vaccination: Key findings

Researchers explore the risks of cardiovascular and cerebrovascular events following vaccination against the COVID-19.

3 Oct 2024

Targeting brain lesions with TMS shows promise in treating PTSD in veterans

Researchers have identified specific brain lesions associated with reduced PTSD symptoms in veterans, providing a potential noninvasive neuromodulation target. TMS applied to this PTSD circuit could offer new hope for effective treatment.

26 Sep 2024

Neuroactive drugs show promising anti-glioblastoma effects in preclinical trials

Study explores the potential to repurpose neuroactive drugs, originally approved for neurological disorders, for the treatment of glioblastoma. Vortioxetine, an antidepressant, showed promising anti-glioblastoma activity, significantly reducing tumor size in preclinical trials.

24 Sep 2024

Psilocybin shows promise for treating depression and improving well-being

A direct comparison between the experimental psychedelic drug psilocybin and a standard SSRI antidepressant shows similar improvement of depressive symptoms, but that psilocybin offers additional longer-term benefits.

22 Sep 2024

Brain scans reveal link between SSRI use and cognitive function

Researchers have found that SSRI (Selective Serotonin Reuptake Inhibitors) antidepressants have the potential to improve certain cognitive functions, such as verbal memory. They measured brain function in patients before and after taking the SSRI escitalopram and correlated this to a drop in the level of one of the serotonin receptors in the brain and to cognitive improvements during treatment.

22 Sep 2024

Promising antidepressant offers hope for glioblastoma treatment

Glioblastoma is a particularly aggressive brain tumor that at present is incurable. Cancer doctors can extend patients' life expectancy through operations, radiation, chemotherapy or surgical interventions. Nevertheless, half of patients die within twelve months of diagnosis.

20 Sep 2024

Study highlights limited evidence for antidepressants in treating pain in older adults

University of Sydney research has found people over 65 are being prescribed antidepressants as pain treatment based on international guidelines that use limited evidence.

16 Sep 2024

Depression has a consistent mark in the brain even when symptoms are absent

Persistent salience network growth in depression highlights neurobiological changes, offering potential insights into mood-state shifts and treatment responses.

6 Sep 2024

High-dose psilocybin shows promise for depression treatment

Researchers compare the effectiveness and acceptability of oral monotherapy with psychedelics for the treatment of depressive symptoms.

27 Aug 2024

High dose psilocybin shows similar antidepressant effects to escitalopram

High doses of psilocybin - the active ingredient in magic mushrooms - appears to have a similar effect on depressive symptoms as the selective serotonin reuptake inhibitor (SSRI) drug escitalopram, suggests a systematic review and meta-analysis published in The BMJ today.

21 Aug 2024