Antidepressant News and Research

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Antidepressants are medicines that treat depression. Your doctor can prescribe them for you. They can improve your mood, sleep, appetite and concentration. It may take several weeks for them to help. There are several types of antidepressants. You and your doctor may have to try several before finding what works best for you.

Program aimed at improving the quality of treatment for depression is effective at reducing depression

An intervention for adolescents aimed at improving the quality of treatment for depression is effective at reducing depression, according to a study in the January 19 issue of JAMA.

19 Jan 2005

Few smokers make use of the help that is available

Antidepressant medicines, nicotine replacement products, and counseling can all help a smoker stick with that New Year's resolution to kick the habit. But a study by American Cancer Society researchers finds that few smokers make use of the help that is available.

17 Jan 2005

More data needed on what's effective for hot flashes

A University of Michigan expert on menopause says a new study that indicates placebos work as well as antidepressant drugs to help hot flashes shows how much more research is needed about what gives patients relief.

17 Jan 2005

European approval of Cymbalta/Xeristar for treatment of major depressive episodes

Eli Lilly and Company and Boehringer Ingelheim announced today that Cymbalta/Xeristar (duloxetine hydrochloride)(+) has been granted marketing authorization by the European Commission for the treatment of major depressive episodes.

5 Jan 2005

Genaissance patent for novel methods to correlate genetics with drug safety and efficacy

Genaissance Pharmaceuticals received a Notice of Allowance from the United States Patent and Trademark Office for a patent claiming methods for identifying correlations between the safety and efficacy of drugs and patients' unique genetic signatures.

4 Jan 2005

Mutant gene that starves the brain of serotonin 10 times more prevalent in depressed patients

A mutant gene that starves the brain of serotonin, a mood-regulating chemical messenger, has been discovered and found to be 10 times more prevalent in depressed patients than in control subjects, report researchers funded by the National Institutes of Health’s National Institute of Mental Health (NIMH) and National Heart Lung and Blood Institute (NHLBI).

21 Dec 2004

Newly discovered genetic defect might represent an important risk factor for major depression

A newly discovered genetic defect might represent an important risk factor for major depression, a condition which effects 20 million people in the U.S., according to Duke University Medical Center researchers.

13 Dec 2004

Review findings released on the safety of antidepressants (SSRI's)

The Medicines and Healthcare products Regulatory Agency (MHRA) issued new advice to patients and doctors about the group of antidepressants known as SSRI's, today.

6 Dec 2004

Adding a commonly used dietary supplement to antidepressants may improve treatment

Massachusetts General Hospital (MGH) researchers have found that adding the nutritional supplement SAMe to a standard antidepressant may be helpful to patients who have not responded to single-drug treatment for clinical depression.

30 Nov 2004

High-quality care for depression can improve productivity at work

A two-year program for depressed employees treated at 12 primary care practices nationwide improved productivity at work by an average of 6 percent, or an estimated annual value of $1,491 per depressed full-time employee.

24 Nov 2004

SSRI's increase risk of abnormal bleeding

New users of selective serotonin reuptake inhibitors (SSRIs, a type of antidepressant) have an increased risk of being admitted to the hospital for abnormal bleeding, according to an article in the November 22 issue of The Archives of Internal Medicine.

23 Nov 2004

Transcranial Magnetic Stimulation to treat major depression

Psychiatrists at Rush University Medical Center are testing a noninvasive technique that uses repeated short bursts of magnetic energy to stimulate nerve cells in the brain to treat major depression.

20 Nov 2004

Postpartum depression: Beyond the 'Baby Blues'

In a culture where giving birth is often believed to be the most joyful moment in life, many women instead feel tired, sad, anxious, distracted and depressed after the baby is born.

18 Nov 2004

Children throughout the world are increasingly being prescribed antidepressants

Children throughout the world are increasingly being prescribed antidepressants and other drugs designed to calm or stimulate the brain, finds research in Archives of Disease in Childhood. Prescription rates increased the most in the UK, the research suggests.

17 Nov 2004

Antidepressants may help people quit smoking when used in conjunction with nicotine patches

When used with a transdermal nicotine patch, nortriptyline—an antidepressant medication—may aid in smoking cessation, according to an article in the November 8 issue of The Archives of Internal Medicine, one of the JAMA/Archives journals.

8 Nov 2004

Quitting smoking can be made easier with long-term comprehensive drug and psychological interventions

People who want to quit smoking have an improved chance of success if they receive long-term comprehensive drug and psychological interventions, according to a new study by UCSF researchers.

4 Nov 2004

Long-term medication and counseling helps smokers quit

People who want to quit smoking have an improved chance of success if they receive long-term comprehensive drug and psychological interventions, according to a new study by UCSF researchers.

1 Nov 2004

New advice on prescribing anti-depressants

New Zealands's Medsafe has sent a letter to all prescribers informing them about new advice relating to the known risks and benefits associated with prescribing medications to treat depression in young people and in adults.

22 Oct 2004

Adults who were abused or neglected as children tend to visit doctors more often

"Many patients visit doctors with symptoms that cannot be explained by underlying physical disease," says researcher Francis Creed, M.D., of the University of Manchester. "Common examples are headache, abdominal and chest pains and constant tiredness."

21 Oct 2004

Awareness helps primary doctors prevent patients' suicide

Although few of their patients commit suicide in a year, primary care physicians should use office visits to note possible risk factors for suicidal behavior, bolstered by candid discussions if needed, according to a review of recent research.

18 Oct 2004