Antifungal News and Research

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Researchers identify microbial cooperation as one of the causes of drug tolerance

The treatment of fungal infections is often hampered by fungal pathogens that do not respond, or are tolerant, against anti-fungal drugs.

23 Mar 2022

Key mechanism that increases drug tolerance among microbial communities revealed

Research from the Francis Crick Institute has revealed a key mechanism which increases tolerance to drugs amongst microbial communities.

22 Mar 2022

Pathogen works with drug to clear fungal infection, study shows

Pathogens don't always work against drug treatments. Sometimes, they can strengthen them, according to a new University of Maine study.

15 Mar 2022

Whole-genome sequencing project sheds new light on the diversity of Candida glabrata

New research from the University of Exeter reports the largest ever whole-genome sequencing project for the potentially fatal yeast infection Candida glabrata from hospitals across Scotland.

3 Mar 2022

UTSA awarded $6.8 million grant to establish a Coccidioidomycosis Collaborative Research Center

Mycology and immunology researchers from The University of Texas at San Antonio have been selected to receive a five-year, $6.8 million grant from the National Institutes of Health to establish a San Antonio-based Coccidioidomycosis Collaborative Research Center (SA-CCRC) focused on developing therapeutics and vaccines against coccidioidomycosis.

8 Feb 2022

Compounds used to fight fungal diseases in plants may be driving antimicrobial resistance

New research from the University of Georgia has shown, for the first time, that compounds used to fight fungal diseases in plants are causing resistance to antifungal medications used to treat people.

8 Feb 2022

Roswell Park scientists identify a potential new treatment target for pancreatic cancer

Scientists at Roswell Park Comprehensive Cancer Center have identified a potential new target for the treatment of pancreatic cancer.

3 Feb 2022

Research may lead to new treatment options for Crohn's disease patients

Results of a new study by researchers at Case Western Reserve University represent a step toward improving our understanding of Crohn's disease and the factors that cause its intestinal inflammation.

10 Jan 2022

Study reveals molecular architecture of fungal cell walls and structural responses to stress

In a new study published in Nature Communications, Associate Professor Tuo Wang and his research team from the Department of Chemistry at Louisiana State University revealed the molecular architecture of fungal cell walls and the structural responses to stresses, aiding the development of antifungal drugs targeting cell wall components.

21 Nov 2021

Researchers identify compounds that tackle fungal infections in a new way

Current medications aren't particularly effective against fungi. The situation is becoming more challenging because these organisms are developing resistance to antimicrobial treatments, just as bacteria are.

17 Nov 2021

Newly identified proteins in fungal biofilms provide potential drug targets to impair antimicrobial defenses

The microbes that make us sick often have ways to evade our attacks against them. Perhaps chief among these strategies is a sticky, armor-like goo, called the biofilm matrix, that encases clusters of disease-causing organisms.

12 Nov 2021

Clinical trial shows no benefit of tamoxifen in treating deadly fungal meningitis

Hopes that tamoxifen could improve survival for a deadly form of fungal meningitis have been dashed by clinical trial results published in eLife.

26 Oct 2021

Antiviral activity of wheat germ Agglutinin against SARS-CoV-2

A new study reports the antiviral activity of WGA against SARS-CoV-2 and its two Variants of Concern - Alpha and Beta.

4 Oct 2021

New nanobiotechnology shows remarkable ability to battle dangerous fungal infections

They’re roughly the same size as a coronavirus particle, and 1000 times smaller than a human hair, yet newly engineered nanoparticles developed by scientists at the University of South Australia, are punching well above their weight when it comes to treating drug-resistant fungal infections.

17 Aug 2021

Novel cold-tolerant bacterium produces a red bio-pigment with germ-killing properties

A team of researchers from Shoolini University, Himachal Pradesh, India have discovered a psychrophilic bacterial strain, called Rhodonellum psychrophilum GL8, at the high altitude Pangong Tso Lake in the Himalayas.

12 Jul 2021

The use of flavonoids as antiviral agents against SARS-CoV-2

Researchers in Iran have undertaken a comprehensive review of flavonoids and their antiviral potential against SARS-CoV-2.

2 Jul 2021

Researchers develop smart wound dressings with built-in healing sensors

Researchers have developed smart wound dressings with built-in nanosensors that glow to alert patients when a wound is not healing properly.

28 Jun 2021

Over-the-counter fungicide holds potential to disrupt steroid hormone levels

The active ingredient in medicines commonly used to treat yeast infections has the potential to disrupt steroid hormone levels, according to a study from the National Food Institute, Technical University of Denmark.

16 Jun 2021

Bioactive packaging can keep strawberries fresh for up to 12 days

Québec produces more strawberries than any other Canadian province. Strawberries are delicate and difficult to keep fresh. In response to this challenge, Monique Lacroix, a professor at at the Institut national de la recherche scientifique, and her team have developed a packaging film that can keep strawberries fresh for up to 12 days.