Antigen News and Research

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Study: T cells play a vital role in controlling SARS-CoV-2 during acute phase of infection

Ever since SARS-CoV-2 first appeared, researchers have been trying to understand whether sometimes the immune system does more harm than good during the acute phase of COVID-19. The latest study by researchers at La Jolla Institute for Immunology clearly argues in favor of the immune system.

17 Sep 2020

Optimal antibody combinations and Fc binding inhibit SARS-CoV-2 in vivo

A recent study by researchers at the University of North Carolina at Chapel Hill and The Rockefeller University and published on the preprint server bioRxiv in September 2020 shows that a combination of neutralizing antibodies with intact Fc effector function can effectively reduce the viral load and prevent infection.

17 Sep 2020

Anti-CD73 molecule CPI-006 activates B cell responses to SARS-CoV-2

As the COVID-19 pandemic continues to cause an immense impact across many parts of the world, the role played by immune responses is becoming more evident every day. A recent funded paper published on the preprint server medRxiv* in September 2020 reports the initiation of a Phase I trial of a drug that increases antibody and cell-mediated immune responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

17 Sep 2020

Study shows how the body's immune system finds intruding or damaged cells

Research led by Dr. Wonmuk Hwang has led to better understanding on how components of the body's immune system find intruding or damaged cells, which could lead to novel approaches to viral and cancer treatments.

17 Sep 2020

Self-assembling nanoparticles as a way towards next-generation COVID-19 vaccines

In a promising study by US researchers, the receptor-binding domain (RBD) and stabilized spike glycoprotein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were displayed on nanoparticles as vaccine antigens and elicited potent immune responses.

16 Sep 2020

Candidate monoclonal antibody shows hope as COVID-19 treatment

Researchers in the United States have described the effectiveness of a candidate monoclonal antibody currently being evaluated in a Phase 1 trial as a therapy for coronavirus disease 2019 (COVID-19) and its causative agent, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

16 Sep 2020

Lack of antigen test reporting leaves country ‘blind to the pandemic’

More than 20 states either don't release or have incomplete data on the rapid antigen tests now considered key to containing the coronavirus, which has sickened more than 6 million Americans.

16 Sep 2020

Study highlights role of specific protein in the mass production of antibodies

Antibodies play a fundamental role in medicine, and antibody-mediated immune response is the ultimate target in the quest for a vaccine to defeat the current pandemic.

16 Sep 2020

SARS-CoV-2 infection severity linked to superior humoral immunity against the S-protein

In a recent bioRxiv* preprint paper, Jenna J. Guthmiller et al., focus on the acute infection of SARS-CoV-2 and observe that the humoral immunity is distinctive with the infection stage and viral antigens.

16 Sep 2020

Patients with more severe SARS-CoV-2 infection exhibit larger antibody response

Researchers in the United States have found that individuals who develop more severe disease following infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mount a larger antibody and memory B cell response during both acute infection and convalescence.

15 Sep 2020

New nanomedicine is efficient and less aggressive than conventional prostate cancer therapy

Prostate cancer is the most common type of cancer among European men; its incidence surpasses 100 cases per 100,000 people.

15 Sep 2020

New antibody assay for COVID-19 promises sensitive mass-scale detection

A new paper by researchers at McMaster University and Hamilton Health Sciences, published on the preprint server medRxiv in September 2020, reports on the development of a serologic assay that is suitable for sensitive high-throughput antibody testing for COVID-19.

15 Sep 2020

Medical experts emphasize new framework for future efforts to offer specific guidance on right-sizing care

Medical experts have worked for decades to improve the chances that patients will get the scans, routine tests and medicines that can do them the most good - and avoid the ones that won't help them at all.

15 Sep 2020

Computational model can help identify best allocation plans for distributing test kits

Getting accurate, timely information on COVID-19 cases is one of the major challenges facing policymakers as they make decisions about public health and the economy.

15 Sep 2020

Bio-Rad launches StarBright Violet 515 Dye for use in flow cytometry

Bio-Rad Laboratories, Inc., a global leader of life science research and clinical diagnostic products, today announced the launch of StarBright Violet 515 Dye, the first of a new range of unique fluorescent nanoparticles, for use in flow cytometry.

From Bio-Rad Laboratories 15 Sep 2020

3D printed nanoparticle biosensing platform detects SARS-CoV-2 antibodies within seconds

Pandemics caused by novel infectious agents like the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Zika, or Ebola virus seriously impact human health and lives while also overwhelming health care systems all over the world. Early detection and diagnosis allow isolation of the infected patients and contact tracing, which can mitigate the spread of the virus and save lives, especially when a significant number of the patients are asymptomatic.

14 Sep 2020

Combining nanotechnology with immunotherapy to fight deadly metastatic breast cancer

A team of scientists led by a researcher at the Case Western Reserve University School of Medicine is making strides to fight deadly metastatic breast cancer by combining nanotechnology with immunotherapy.

14 Sep 2020

India's whole-virion inactivated SARS-CoV-2 vaccine shows promise

Researchers in India have conducted a preclinical study demonstrating the safety and efficacy of a new candidate vaccine for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent that causes coronavirus disease 2019 (COVID-19).

13 Sep 2020

New, rapid test detects ovarian cancer more accurately

The CA125 antigen, a plasma membrane glycoprotein found in the tissues of the female reproductive tract, is commonly used for the detection of ovarian cancer but works poorly on its own in identifying early stage cancers.

11 Sep 2020

New review explores the role of antibodies and T-cells towards an effective COVID vaccine

More than 100 companies have rushed into vaccine development against COVID-19 as the U.S. government pushes for a vaccine rollout at "warp speed" -- possibly by the end of the year -- but the bar set for an effective, long-lasting vaccine is far too low and may prove dangerous, according to Marc Hellerstein of the University of California, Berkeley.

11 Sep 2020

Antigen News and Research

Study: T cells play a vital role in controlling SARS-CoV-2 during acute phase of infection

Optimal antibody combinations and Fc binding inhibit SARS-CoV-2 in vivo

Anti-CD73 molecule CPI-006 activates B cell responses to SARS-CoV-2

Study shows how the body's immune system finds intruding or damaged cells

Self-assembling nanoparticles as a way towards next-generation COVID-19 vaccines

Candidate monoclonal antibody shows hope as COVID-19 treatment

Lack of antigen test reporting leaves country ‘blind to the pandemic’

Study highlights role of specific protein in the mass production of antibodies

SARS-CoV-2 infection severity linked to superior humoral immunity against the S-protein

Patients with more severe SARS-CoV-2 infection exhibit larger antibody response

New nanomedicine is efficient and less aggressive than conventional prostate cancer therapy

New antibody assay for COVID-19 promises sensitive mass-scale detection

Medical experts emphasize new framework for future efforts to offer specific guidance on right-sizing care

Computational model can help identify best allocation plans for distributing test kits

Bio-Rad launches StarBright Violet 515 Dye for use in flow cytometry

3D printed nanoparticle biosensing platform detects SARS-CoV-2 antibodies within seconds

Combining nanotechnology with immunotherapy to fight deadly metastatic breast cancer

India's whole-virion inactivated SARS-CoV-2 vaccine shows promise

New, rapid test detects ovarian cancer more accurately

New review explores the role of antibodies and T-cells towards an effective COVID vaccine

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