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'Pocket' project develops new low-cost test for accurate TB detection

Tuberculosis (TB) is a major global health issue. According to the World Health Organisation (WHO), every year there are worldwide 8.8 million new active TB cases and nearly 2 million TB deaths - 5000 every day - mostly in the poorest communities of the developing world.

19 Sep 2017

Researchers identify potential gonorrhea vaccine candidates

Researchers at Oregon State University have identified a pair of proteins that show promise as the basis for a gonorrhea vaccine.

19 Sep 2017

New discovery by TSRI scientists could speed efforts to develop effective HIV vaccine

Scientists at The Scripps Research Institute have made a discovery that could speed efforts to develop a successful HIV vaccine.

14 Sep 2017

Nanoparticle bling could increase sensitivity of test strips for better cancer detection

The most common test strip people might think of for diagnosis is a home pregnancy test. Pregnant women have steadily increasing levels of the biomarker human chorionic gonadotropin (hCG), which is easily detectable in urine and a thin, colorful strip of antibodies will appear when hCG is present.

13 Sep 2017

‘Nanoswitches’ could be key to faster, more sensitive tests for detection of biomarkers

Engineered strands of DNA -- nanoscale tools called "nanoswitches" -- could be the key to faster, easier, cheaper and more sensitive tests that can enable high-fidelity detection of biomarkers indicating the presence of different diseases, viral strains and even genetic variabilities as subtle as a single-gene mutation.

12 Sep 2017

Researchers reveal new approach to precisely identify and treat prostate cancer

Researchers have demonstrated a new, effective way to precisely identify and localize prostate cancer tumors while protecting healthy tissue and reducing side effects.

7 Sep 2017

Blood tumor markers could be useful in monitoring therapeutic outcomes for lung cancer patients

For many years, oncologists have known that cancers can secrete complex molecules into the blood and that levels of these molecules can be easily measured. These so-called 'tumor markers' are traditionally associated with a single dominant cancer type, for example Prostate Specific Antigen (PSA) linked to prostate cancer, Carcinoembryonic antigen (CEA) to colorectal cancer, CA125 to ovarian cancer, CA19.9 to pancreatic cancer and CA27.29 to breast cancer.

6 Sep 2017

New portable allergen-detection system could help prevent trips to emergency room

For kids and adults with food allergies, a restaurant outing can be a fraught experience. Even when care is taken, freshly prepared or packaged meals can accidentally become cross-contaminated with an offending food and trigger a reaction.

6 Sep 2017

Prostate cancer screening reduces cancer deaths finds new analysis

There has been much debate regarding the utility of prostate cancer screening in reducing the rates of deaths due to this cancer among men. While the ERSPC (European Randomized Study of Screening for Prostate Cancer) suggests that screening reduced prostate cancer deaths, the PLCO (Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial) found that regular screening does not reduce the cancer death rates in prostate cancer. Researchers thus looked at the actual picture as to which of these – ERSPC or PLCO are correct.

5 Sep 2017

FDA approves drug to treat patients with newly diagnosed CD33-positive AML

The U.S. Food and Drug Administration today approved Mylotarg (gemtuzumab ozogamicin) for the treatment of adults with newly diagnosed acute myeloid leukemia whose tumors express the CD33 antigen (CD33-positive AML).

1 Sep 2017

Pfizer receives FDA approval for new therapy to treat adults and children with AML

Pfizer Inc. today announced that the U.S. Food and Drug Administration approved MYLOTARG (gemtuzumab ozogamicin) for adults with newly diagnosed CD33-positive acute myeloid leukemia (AML), and adults and children 2 years and older with relapsed or refractory CD33-positive AML.

1 Sep 2017

UChicago Medicine working with Novartis to offer breakthrough gene therapy for pediatric ALL patients

The University of Chicago Medicine is one of a limited number of U.S. sites working to offer a breakthrough gene therapy for pediatric acute lymphoblastic leukemia (ALL), which was just approved by the U.S. Food and Drug Administration.

31 Aug 2017

Researcher uses gold nanoparticles and lasers to target bladder cancer

A University of Colorado Cancer Center study takes a new approach to killing cancer: Why not fry it into oblivion with vibrating gold nanoparticles? "But what about the frickin' lasers?" you may ask. Don't worry. There are lasers. And bioluminescence too.

31 Aug 2017

FDA makes the first gene therapy Kymriah available for treatment of pediatric ALL

The U.S. Food and Drug Administration (FDA) has issued a press release making the first even gene therapy available for treatment of children with a form of acute lymphoblastic leukemia (ALL).

30 Aug 2017

$Novartis gets FDA approval for novel immunocellular therapy to treat relapsed or refractory B-cell ALL$

Novartis gets FDA approval for novel immunocellular therapy to treat relapsed or refractory B-cell ALL

Novartis announced today that the US Food and Drug Administration has approved Kymriah (tisagenlecleucel) suspension for intravenous infusion, formerly CTL019, the first chimeric antigen receptor T cell (CAR-T) therapy, for the treatment of patients up to 25 years of age with B-cell precursor acute lymphoblastic leukemia (ALL) that is refractory or in second or later relapse.

30 Aug 2017

New biomedical tool using nanoparticles could improve therapies for many diseases

A new biomedical tool using nanoparticles that deliver transient gene changes to targeted cells could make therapies for a variety of diseases -; including cancer, diabetes and HIV -; faster and cheaper to develop, and more customizable.

30 Aug 2017

FDA approves first cell-based gene therapy for use in the United States

The U.S. Food and Drug Administration issued a historic action today making the first gene therapy available in the United States, ushering in a new approach to the treatment of cancer and other serious and life-threatening diseases.

30 Aug 2017

Researchers develop new approach to efficiently produce versatile antibody therapies

A group of researchers has developed an approach to efficiently produce antibodies that can bind to two different target molecules simultaneously, a long-desired innovation in the field of cancer immunotherapy.

29 Aug 2017

GW study to explore the body's natural defenses against HIV

A research team at the George Washington University School of Medicine and Health Sciences will study the body's natural defenses against HIV and look for ways to eliminate the infectious HIV reservoirs in the white blood cells of people taking antiretroviral therapy.

28 Aug 2017

Simultaneous treatment with anti-PD1 and anti-OX40 cancer therapies may have detrimental effect

Concurrent administration of the T-cell stimulating anti-OX40 antibody and the immune checkpoint inhibitor anti-PD1 antibody attenuated the effect of anti-OX40 and resulted in poor treatment outcomes in mice.

28 Aug 2017

Antigen News and Research

'Pocket' project develops new low-cost test for accurate TB detection

Researchers identify potential gonorrhea vaccine candidates

New discovery by TSRI scientists could speed efforts to develop effective HIV vaccine

Nanoparticle bling could increase sensitivity of test strips for better cancer detection

‘Nanoswitches’ could be key to faster, more sensitive tests for detection of biomarkers

Researchers reveal new approach to precisely identify and treat prostate cancer

Blood tumor markers could be useful in monitoring therapeutic outcomes for lung cancer patients

New portable allergen-detection system could help prevent trips to emergency room

Prostate cancer screening reduces cancer deaths finds new analysis

FDA approves drug to treat patients with newly diagnosed CD33-positive AML

Pfizer receives FDA approval for new therapy to treat adults and children with AML

UChicago Medicine working with Novartis to offer breakthrough gene therapy for pediatric ALL patients

Researcher uses gold nanoparticles and lasers to target bladder cancer

FDA makes the first gene therapy Kymriah available for treatment of pediatric ALL

Novartis gets FDA approval for novel immunocellular therapy to treat relapsed or refractory B-cell ALL

New biomedical tool using nanoparticles could improve therapies for many diseases

FDA approves first cell-based gene therapy for use in the United States

Researchers develop new approach to efficiently produce versatile antibody therapies

GW study to explore the body's natural defenses against HIV

Simultaneous treatment with anti-PD1 and anti-OX40 cancer therapies may have detrimental effect

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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