Antiretroviral News and Research

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HIV-positive people with severe immunosuppression, APOE4 gene may have increased risk for dementia

People living with the human immunodeficiency virus (HIV) who have a history of severe immunosuppression and at least one copy of the Alzheimer's disease-related gene variant APOE4, might see a compounded adverse effect on the circuitry that impacts memory.

22 Feb 2021

Antimicrobial resistance to critical drugs spirals in low- and middle-income countries

As antibiotic use grows in lower-income countries so does antibiotic resistance, says report.

20 Feb 2021

New research yields potential drug target against HIV

Humans possess a formidable multi-layered defense system that protects us against viral infections. Better understanding of these defenses and the tricks that viruses use to evade them could open novel avenues for treating viral infections and possibly other diseases.

11 Feb 2021

HIV: New therapeutic approach to restore the effectiveness of immune cells

Prompted by the need to improve conventional treatments for people infected with the human immunodeficiency virus (HIV-1), a team from the Institut national de la recherche scientifique has identified a therapeutic approach to restore the effectiveness of immune cells.

8 Feb 2021

Researchers report trial results of rectal microbicides at HIV R4P Virtual Conference

Researchers seeking to develop on-demand and behaviorally congruent HIV prevention options for people who practice anal sex are reporting the results of three early phase clinical trials of rectal microbicides at this week's HIV Research for Prevention (HIV R4P) Virtual Conference.

3 Feb 2021

WHO recommends dapivirine vaginal ring as additional HIV prevention choice for at-risk women

WHO today recommended that the dapivirine vaginal ring (DPV-VR) may be offered as an additional prevention choice for women at substantial risk of HIV infection as part of combination prevention approaches.

1 Feb 2021

Use of antiviral and antiretroviral medication could have detrimental impact on crops

The increased global use of antiviral and antiretroviral medication could have a detrimental impact on crops and potentially heighten resistance to their effects, new research has suggested.

29 Jan 2021

Socioeconomic conditions linked to high viral load despite treatment for HIV patients in Ethiopia

For those who are diagnosed and have begun treatment for HIV, it is standard practice to regularly monitor viral load in the blood to assess response to treatment.

25 Jan 2021

FDA approves first injectable, complete regimen for HIV-1 infection in adults

The U.S. Food and Drug Administration today approved Cabenuva (cabotegravir and rilpivirine, injectable formulation) as a complete regimen for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in adults to replace a current antiretroviral regimen in those who are virologically suppressed on a stable antiretroviral regimen with no history of treatment failure and with no known or suspected resistance to either cabotegravir or rilpivirine.

21 Jan 2021

Researchers measure brain volume differences in HIV-infected individuals

Nearly 38 million people around the world are living with HIV, which, with access to treatment, has become a lifelong chronic condition. Understanding how infection changes the brain, especially in the context of aging, is increasingly important for improving both treatment and quality of life.

16 Jan 2021

Scientists determine ideal dose of stem cells to control HIV

Scientists have determined the optimal conditions following a stem cell transplant that could control HIV without the need of an everyday pill, according to a study published today in eLife.

12 Jan 2021

Study explores women's interest in long-acting injectable antiretroviral therapy

A study led by Columbia University Mailman School of Public Health researchers examines attitudes toward long-acting injectable (LAI) HIV therapies, among women with a history of injection--including medical purposes and substance use. The findings appear in the journal AIDS Patient Care and STDs.

7 Jan 2021

Impaired blood vessel and kidney function underlie heart disease risk in people with HIV

A new study has found impaired blood vessel function in those living with human immunodeficiency virus (HIV).

16 Dec 2020

The vaginal microbiome may impact the efficacy of HIV prevention therapy

A new study has revealed that vaginal microbial communities are linked with an increased risk of HIV acquisition and may also impact the efficacy of PrEP.

3 Dec 2020

HIV 'wonder drug' may not be as effective as hoped in sub-Saharan Africa, study suggests

Dolutegravir, the current first-line treatment for HIV, may not be as effective as hoped in sub-Saharan Africa, suggests new research published on World AIDS Day. The study finds that this so-called 'wonder drug' may be less effective in patients resistant to older drugs.

1 Dec 2020

SEAR implemented measures for successful continuation of essential HIV services during COVID 19

The COVID-19 pandemic was predicted to and has had a major impact on the essential HIV health services in the South East Asia Region (SEAR), putting at risk the benefits accrued over the last two decades. Apart from the risks posed by the virus to the individual health of people living with HIV (PLHIV), COVID-19 has disrupted essential services causing considerable delays in the delivery of medicines and other health commodities.

1 Dec 2020

Researchers successfully edit SIV virus from genomes of non-human primates

Taking a major step forward in HIV research, scientists at the Lewis Katz School of Medicine at Temple University have successfully edited SIV - a virus closely related to HIV, the cause of AIDS - from the genomes of non-human primates.

1 Dec 2020

HIV and TB laboratory systems used to scale up COVID-19 testing in Africa

Many countries in resource-limited settings have high HIV, malaria, tuberculosis, hepatitis, and/or sexually transmitted infection (STI) burdens.

30 Nov 2020

UC San Diego chosen to lead an international $28-million grant for HIV/AIDS clinical trials

University of California San Diego Collaborative Clinical Trials Unit has been selected by the National Institutes of Health to lead and administer an international seven-year, $28-million grant for science-driven clinical trials that deliver innovative, efficient results needed to turn the corner on the HIV/AIDS pandemic.

30 Nov 2020

IPM announces WHO's prequalification of dapivirine ring to reduce women’s HIV risk

The nonprofit International Partnership for Microbicides is pleased to announce the World Health Organization's prequalification of the dapivirine ring, a monthly vaginal ring to reduce women's HIV risk.

30 Nov 2020

Antiretroviral News and Research

HIV-positive people with severe immunosuppression, APOE4 gene may have increased risk for dementia

Antimicrobial resistance to critical drugs spirals in low- and middle-income countries

New research yields potential drug target against HIV

HIV: New therapeutic approach to restore the effectiveness of immune cells

Researchers report trial results of rectal microbicides at HIV R4P Virtual Conference

WHO recommends dapivirine vaginal ring as additional HIV prevention choice for at-risk women

Use of antiviral and antiretroviral medication could have detrimental impact on crops

Socioeconomic conditions linked to high viral load despite treatment for HIV patients in Ethiopia

FDA approves first injectable, complete regimen for HIV-1 infection in adults

Researchers measure brain volume differences in HIV-infected individuals

Scientists determine ideal dose of stem cells to control HIV

Study explores women's interest in long-acting injectable antiretroviral therapy

Impaired blood vessel and kidney function underlie heart disease risk in people with HIV

The vaginal microbiome may impact the efficacy of HIV prevention therapy

HIV 'wonder drug' may not be as effective as hoped in sub-Saharan Africa, study suggests

SEAR implemented measures for successful continuation of essential HIV services during COVID 19

Researchers successfully edit SIV virus from genomes of non-human primates

HIV and TB laboratory systems used to scale up COVID-19 testing in Africa

UC San Diego chosen to lead an international $28-million grant for HIV/AIDS clinical trials

IPM announces WHO's prequalification of dapivirine ring to reduce women’s HIV risk

One Health, One Mission: The World Organisation for Animal Health on the AMR Frontline

Uniting Against Resistance: The World Health Organization for World Antimicrobial Awareness Week 2023

Tackling Antimicrobial Resistance: A Conversation with Dr. Beverley Isherwood

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