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Socioeconomic conditions linked to high viral load despite treatment for HIV patients in Ethiopia

For those who are diagnosed and have begun treatment for HIV, it is standard practice to regularly monitor viral load in the blood to assess response to treatment.

25 Jan 2021

FDA approves first injectable, complete regimen for HIV-1 infection in adults

The U.S. Food and Drug Administration today approved Cabenuva (cabotegravir and rilpivirine, injectable formulation) as a complete regimen for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in adults to replace a current antiretroviral regimen in those who are virologically suppressed on a stable antiretroviral regimen with no history of treatment failure and with no known or suspected resistance to either cabotegravir or rilpivirine.

21 Jan 2021

Researchers measure brain volume differences in HIV-infected individuals

Nearly 38 million people around the world are living with HIV, which, with access to treatment, has become a lifelong chronic condition. Understanding how infection changes the brain, especially in the context of aging, is increasingly important for improving both treatment and quality of life.

16 Jan 2021

Scientists determine ideal dose of stem cells to control HIV

Scientists have determined the optimal conditions following a stem cell transplant that could control HIV without the need of an everyday pill, according to a study published today in eLife.

12 Jan 2021

Study explores women's interest in long-acting injectable antiretroviral therapy

A study led by Columbia University Mailman School of Public Health researchers examines attitudes toward long-acting injectable (LAI) HIV therapies, among women with a history of injection--including medical purposes and substance use. The findings appear in the journal AIDS Patient Care and STDs.

7 Jan 2021

Impaired blood vessel and kidney function underlie heart disease risk in people with HIV

A new study has found impaired blood vessel function in those living with human immunodeficiency virus (HIV).

16 Dec 2020

The vaginal microbiome may impact the efficacy of HIV prevention therapy

A new study has revealed that vaginal microbial communities are linked with an increased risk of HIV acquisition and may also impact the efficacy of PrEP.

3 Dec 2020

HIV 'wonder drug' may not be as effective as hoped in sub-Saharan Africa, study suggests

Dolutegravir, the current first-line treatment for HIV, may not be as effective as hoped in sub-Saharan Africa, suggests new research published on World AIDS Day. The study finds that this so-called 'wonder drug' may be less effective in patients resistant to older drugs.

1 Dec 2020

SEAR implemented measures for successful continuation of essential HIV services during COVID 19

The COVID-19 pandemic was predicted to and has had a major impact on the essential HIV health services in the South East Asia Region (SEAR), putting at risk the benefits accrued over the last two decades. Apart from the risks posed by the virus to the individual health of people living with HIV (PLHIV), COVID-19 has disrupted essential services causing considerable delays in the delivery of medicines and other health commodities.

1 Dec 2020

Researchers successfully edit SIV virus from genomes of non-human primates

Taking a major step forward in HIV research, scientists at the Lewis Katz School of Medicine at Temple University have successfully edited SIV - a virus closely related to HIV, the cause of AIDS - from the genomes of non-human primates.

1 Dec 2020

HIV and TB laboratory systems used to scale up COVID-19 testing in Africa

Many countries in resource-limited settings have high HIV, malaria, tuberculosis, hepatitis, and/or sexually transmitted infection (STI) burdens.

30 Nov 2020

UC San Diego chosen to lead an international $28-million grant for HIV/AIDS clinical trials

University of California San Diego Collaborative Clinical Trials Unit has been selected by the National Institutes of Health to lead and administer an international seven-year, $28-million grant for science-driven clinical trials that deliver innovative, efficient results needed to turn the corner on the HIV/AIDS pandemic.

30 Nov 2020

IPM announces WHO's prequalification of dapivirine ring to reduce women’s HIV risk

The nonprofit International Partnership for Microbicides is pleased to announce the World Health Organization's prequalification of the dapivirine ring, a monthly vaginal ring to reduce women's HIV risk.

30 Nov 2020

HIV alters SARS-CoV-2 immune response without affecting COVID-19 symptoms or outcomes

In a preprint paper published on the medRxiv server, a team of researchers from various institutions in South Africa, the UK, and Europe discuss how they determined the impact of HIV on the COVID-19 immune response in KwaZulu-Natal, South Africa, which is an area with very high HIV prevalence.

26 Nov 2020

Largest clinical trial launched to treat mild-to-moderate COVID-19 patients in Africa

Thirteen African countries and an international network of research institutions have joined forces to launch the largest COVID-19 clinical trial in mild-to-moderate outpatients in Africa.

24 Nov 2020

Discovery of 'Achilles heel' in protein crucial to HIV virulence could lead to new class of drugs

The discovery of a potential "Achilles heel" in Nef, the protein that is crucial to HIV virulence and its capacity to trigger AIDS, paves the way for the development of a new class of drugs against the virus.

17 Nov 2020

Cabotegravir highly effective in preventing HIV among women

UNAIDS has been strongly encouraged by groundbreaking new study results showing that the antiretroviral medicine cabotegravir administered by an injection every two months – prevents HIV among women.

10 Nov 2020

Trial results show CAB LA is more effective in preventing HIV acquisition in women

The HIV Prevention Trials Network study (HPTN 084) on the safety and efficacy of the long-acting injectable antiretroviral drug cabotegravir (CAB LA), for pre-exposure prophylaxis (PrEP) in HIV-uninfected women, was stopped early by the trial Data and Safety Monitoring Board (DSMB) as results showed CAB LA to be highly effective in preventing HIV acquisition.

10 Nov 2020

Study identifies new cause of inflammation in people living with HIV

While current antiretroviral treatments for HIV are highly effective, data has shown that people living with HIV appear to experience accelerated aging and have shorter lifespans - by up to five to 10 years - compared to people without HIV.

30 Oct 2020

Study: Toxins produced by tube-dwelling anemones have pharmacological potential

Researchers based in Brazil and the United States have completed the first-ever mapping exercise to profile the toxins produced by tube-dwelling anemones, or cerianthids, a family of marine animals belonging to the same phylum (Cnidaria) as sea anemones, jellyfish and corals.

30 Oct 2020

Antiretroviral News and Research

Socioeconomic conditions linked to high viral load despite treatment for HIV patients in Ethiopia

FDA approves first injectable, complete regimen for HIV-1 infection in adults

Researchers measure brain volume differences in HIV-infected individuals

Scientists determine ideal dose of stem cells to control HIV

Study explores women's interest in long-acting injectable antiretroviral therapy

Impaired blood vessel and kidney function underlie heart disease risk in people with HIV

The vaginal microbiome may impact the efficacy of HIV prevention therapy

HIV 'wonder drug' may not be as effective as hoped in sub-Saharan Africa, study suggests

SEAR implemented measures for successful continuation of essential HIV services during COVID 19

Researchers successfully edit SIV virus from genomes of non-human primates

HIV and TB laboratory systems used to scale up COVID-19 testing in Africa

UC San Diego chosen to lead an international $28-million grant for HIV/AIDS clinical trials

IPM announces WHO's prequalification of dapivirine ring to reduce women’s HIV risk

HIV alters SARS-CoV-2 immune response without affecting COVID-19 symptoms or outcomes

Largest clinical trial launched to treat mild-to-moderate COVID-19 patients in Africa

Discovery of 'Achilles heel' in protein crucial to HIV virulence could lead to new class of drugs

Cabotegravir highly effective in preventing HIV among women

Trial results show CAB LA is more effective in preventing HIV acquisition in women

Study identifies new cause of inflammation in people living with HIV

Study: Toxins produced by tube-dwelling anemones have pharmacological potential

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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