Antiretroviral News and Research

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Majority of women prefer LAI HIV therapy over daily pills

A new qualitative study by researchers at Columbia University Mailman School of Public Health found that the majority of women living with HIV would endorse a monthly long acting injectable (LAI) antiretroviral therapy over current daily pills.

22 Apr 2020

Depressive disorders in patients with HIV/AIDS often go unrecognized or untreated

People living with HIV/AIDS are at increased risk of depressive disorders. But all too often, these conditions go unrecognized or untreated, suggests a literature review in the May/June issue of Harvard Review of Psychiatry.

7 Apr 2020

Newly developed laboratory model helps reveal how HIV infection affects the brain

Though many negative repercussions of human immunodeficiency virus infection can be mitigated with the use of antiretroviral therapy, one area where medical advances haven't made as much progress is in the reduction of cognitive impacts.

27 Mar 2020

New test uses saliva sample to provide immediate hepatitis B diagnosis

Viruses are sneaky beings. As the coronavirus pandemic is demonstrating, they cross borders quickly and can be highly contagious before symptoms of disease break out. In many cases of infection, a clear path of transmission cannot be determined.

27 Mar 2020

Immunotherapy combination can shrink viral reservoir in HIV model

Stimulating immune cells with two cancer immunotherapies together can shrink the size of the viral "reservoir" in SIV-infected non-human primates treated with antiviral drugs, researchers have concluded.

16 Mar 2020

Scientists find new way to amplify miRNA in live tumor cells for bioimaging

A good indicator of dysregulation in live cells is a change in their RNA expression. MicroRNA (miRNA), a special type of RNA, is considered a biomarker for carcinogenic cells.

16 Mar 2020

Newer antiretroviral drugs may be the safest, most effective HIV treatment during pregnancy

The antiretroviral drugs dolutegravir and emtricitabine/tenofovir alafenamide fumarate (DTG+FTC/TAF) may comprise the safest and most effective HIV treatment regimen currently available during pregnancy, researchers announced today.

11 Mar 2020

The second person cured from HIV goes public

In the 1980s and early 1990s, the outbreak of HIV and AIDS swept across the globe. Today, more than 70 million people have been infected with HIV, and about 35 million have died from AIDS since the start of the pandemic. However, scientific advances, such as the development of antiretroviral drugs, have enabled people with access to treatment to live long and healthy lives with HIV. But, there is still no vaccine and cure for it. In history, only two persons have been cleared of the infection, one in Berlin and now the second one in London.

10 Mar 2020

Study reports second ever case of a patient to be cured of HIV

A study of the second HIV patient to undergo successful stem cell transplantation from donors with a HIV-resistant gene, finds that there was no active viral infection in the patient's blood 30 months after they stopped anti-retroviral therapy, according to a case report published in The Lancet HIV journal and presented at CROI.

10 Mar 2020

Simple method to prevent HIV greatly increases viral suppression in South Africa, Uganda

In parts of Africa, where the rate of HIV is high, researchers found that using mobile vans to dispense antiretroviral treatment and other care greatly increased viral suppression.

9 Mar 2020

Alcohol Consumption Weakens Bones of People Living with HIV

For people living with HIV, any level of alcohol consumption is associated with lower levels of a protein involved in bone formation, raising the risk of osteoporosis, according to a new study by researchers from the Boston University School of Public Health.

3 Mar 2020

New study uncovers human genes controlling HIV infection

Viruses are parasites. The only way they can grow is by hijacking their hosts. When they infect a human host, viruses use human proteins to multiply and modify the human cells to sustain the infection. At the same time, the human host activates defense mechanisms to fight the infection.

20 Feb 2020

Vitamin E can safely treat fatty liver disease in patients with HIV

A type of fatty liver disease that commonly affects patients with HIV can be safely treated with vitamin E, a McGill-led study has found.

16 Feb 2020

To fight Chinese outbreak, doctors deploy drugs targeting HIV, malaria and Ebola

As the scientific community scrambles to find a drug that can effectively treat tens of thousands of patients sickened by a new respiratory virus, they are trying some surprising remedies: medicines targeting known killers like HIV, Ebola and malaria.

13 Feb 2020

Study gives clues on how to stop HIV reemergence

A new study released today in the Journal of Virology gives insights into how the HIV-1 virus, which often persists in the body despite antiretroviral treatment, reemerges when treatment stops. More importantly, the study also gives clues on how to stop this reemergence from occurring.

12 Feb 2020

Study to evaluate safety of PrEP and dapivirine ring in pregnant women

A woman who is eight-months pregnant is the first participant to be enrolled into a study evaluating the safety and acceptability of two different HIV prevention approaches when used during pregnancy -- the monthly dapivirine vaginal ring, which is currently under regulatory review, and a daily antiretroviral (ARV) pill called Truvada, an approach already approved in several countries and commonly referred to as PrEP, short for pre-exposure prophylaxis.

10 Feb 2020